SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ept'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5ept PEROXIREDOXIN TSA2
(Saccharomyces
cerevisiae) 		4 / 8 PRO H  10
THR H  74
PHE H  39
ASP H 111
 None
 1.13A 1p7lC-5eptH:
undetectable		 1p7lC-5eptH:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5ept PEROXIREDOXIN TSA2
(Saccharomyces
cerevisiae) 		4 / 8 PRO H  10
THR H  74
PHE H  39
ASP H 111
 None
 1.14A 1p7lD-5eptH:
undetectable		 1p7lD-5eptH:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5ept PEROXIREDOXIN TSA2
(Saccharomyces
cerevisiae) 		4 / 8 PRO H  10
THR H  74
PHE H  39
ASP H 111
 None
 1.14A 1rg9A-5eptH:
undetectable		 1rg9A-5eptH:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5ept PEROXIREDOXIN TSA2
(Saccharomyces
cerevisiae) 		4 / 8 PRO H  10
THR H  74
PHE H  39
ASP H 111
 None
 1.15A 1rg9B-5eptH:
undetectable		 1rg9B-5eptH:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5ept PEROXIREDOXIN TSA2
(Saccharomyces
cerevisiae) 		4 / 8 PRO H  10
THR H  74
PHE H  39
ASP H 111
 None
 1.13A 1rg9C-5eptH:
undetectable		 1rg9C-5eptH:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5ept PEROXIREDOXIN TSA2
(Saccharomyces
cerevisiae) 		4 / 8 PRO H  10
THR H  74
PHE H  39
ASP H 111
 None
 1.14A 1rg9D-5eptH:
undetectable		 1rg9D-5eptH:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 5ept PEROXIREDOXIN TSA2
(Saccharomyces
cerevisiae) 		4 / 5 GLY H 113
PRO H  10
ALA H   9
ILE H 135
 None
 0.88A 2aofA-5eptH:
undetectable		 2aofA-5eptH:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TOD_A_DMOA700_1
(PROTEIN (ORNITHINE
DECARBOXYLASE))		 5ept PEROXIREDOXIN TSA2
(Saccharomyces
cerevisiae) 		4 / 6 ASP H 103
PHE H  39
ASP H 111
TYR H 112
 None
 1.34A 2todA-5eptH:
undetectable
2todB-5eptH:
undetectable		 2todA-5eptH:
18.12
2todB-5eptH:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		 5ept PEROXIREDOXIN TSA2
(Saccharomyces
cerevisiae) 		4 / 8 LEU H 108
TYR H 112
PHE H 127
LEU H  37
 None
 0.99A 3i45A-5eptH:
undetectable		 3i45A-5eptH:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5ept PEROXIREDOXIN TSA2
(Saccharomyces
cerevisiae) 		4 / 8 PRO H  10
THR H  74
PHE H  39
ASP H 111
 None
 1.16A 5t8sB-5eptH:
undetectable		 5t8sB-5eptH:
21.74