SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5epv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZW9_A_SAMA801_0 (LEUCINE CARBOXYL METHYLTRANSFERASE 2)	5epv	BLUE-LIGHT-ACTIVATED HISTIDINE KINASE (Brucella abortus)	5 / 12	ILE A 402 SER A 396 GLY A 462 GLY A 426 LEU A 464	None	1.06A	2zw9A-5epvA: undetectable	2zw9A-5epvA: 16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RET_A_SALA201_1 (SALICYLATE BIOSYNTHESIS PROTEIN PCHB)	5epv	BLUE-LIGHT-ACTIVATED HISTIDINE KINASE (Brucella abortus)	5 / 10	VAL A 370 ALA A 469 VAL A 467 MET A 419 ILE A 342	None	1.35A	3retA-5epvA: undetectable 3retB-5epvA: 1.9	3retA-5epvA: 19.50 3retB-5epvA: 19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OR0_A_NPSA602_1 (SERUM ALBUMIN)	5epv	BLUE-LIGHT-ACTIVATED HISTIDINE KINASE (Brucella abortus)	5 / 9	ALA A 394 ALA A 389 LEU A 385 SER A 461 VAL A 429	None ACP A 501 ( 4.4A) None None ACP A 501 ( 4.2A)	1.31A	4or0A-5epvA: 2.1	4or0A-5epvA: 16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_A_ACTA305_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	5epv	BLUE-LIGHT-ACTIVATED HISTIDINE KINASE (Brucella abortus)	3 / 3	THR A 405 MET A 419 HIS A 418	None	0.96A	5uunA-5epvA: 3.7	5uunA-5epvA: 22.41

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2ZW9_A_SAMA801_0","LEUCINE CARBOXYL METHYLTRANSFERASE 2","5epv","BLUE-LIGHT-ACTIVATED HISTIDINE KINASE","Brucella abortus",5,"ILE A 402;SER A 396;GLY A 462;GLY A 426;LEU A 464","None","1.06A","2zw9A-5epvA:undetectable","2zw9A-5epvA:16.12"],["3RET_A_SALA201_1","SALICYLATE BIOSYNTHESIS PROTEIN PCHB;SALICYLATE BIOSYNTHESIS PROTEIN PCHB","5epv","BLUE-LIGHT-ACTIVATED HISTIDINE KINASE","Brucella abortus",5,"VAL A 370;ALA A 469;VAL A 467;MET A 419;ILE A 342","None","1.35A","3retA-5epvA:undetectable;3retB-5epvA:1.9","3retA-5epvA:19.50;3retB-5epvA:19.50"],["4OR0_A_NPSA602_1","SERUM ALBUMIN","5epv","BLUE-LIGHT-ACTIVATED HISTIDINE KINASE","Brucella abortus",5,"ALA A 394;ALA A 389;LEU A 385;SER A 461;VAL A 429","None;ACP A 501 ( 4.4A);None;None;ACP A 501 ( 4.2A)","1.31A","4or0A-5epvA:2.1","4or0A-5epvA:16.41"],["5UUN_A_ACTA305_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN","5epv","BLUE-LIGHT-ACTIVATED HISTIDINE KINASE","Brucella abortus",3,"THR A 405;MET A 419;HIS A 418","None","0.96A","5uunA-5epvA:3.7","5uunA-5epvA:22.41"]]