SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5eq6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_A_GBNA502_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 5eq6 TYPE 4 FIMBRIAL
BIOGENESIS PROTEIN
PILM
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 296
THR A 297
ALA A 298
VAL A 197
 ANP  A 401 (-3.2A)
ANP  A 401 (-4.1A)
None
None
 0.76A 2a1hA-5eq6A:
undetectable
2a1hB-5eq6A:
undetectable		 2a1hA-5eq6A:
22.08
2a1hB-5eq6A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 5eq6 TYPE 4 FIMBRIAL
BIOGENESIS PROTEIN
PILM
(Pseudomonas
aeruginosa) 		4 / 5 LEU A 348
ASP A  16
ALA A 174
ILE A 344
 None
 0.97A 2aofB-5eq6A:
undetectable		 2aofB-5eq6A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5eq6 TYPE 4 FIMBRIAL
BIOGENESIS PROTEIN
PILM
(Pseudomonas
aeruginosa) 		4 / 7 THR A 206
LEU A 207
THR A 215
THR A 218
 None
 0.90A 4z91F-5eq6A:
undetectable
4z91G-5eq6A:
undetectable
4z91H-5eq6A:
undetectable
4z91I-5eq6A:
undetectable
4z91J-5eq6A:
undetectable		 4z91F-5eq6A:
20.95
4z91G-5eq6A:
20.95
4z91H-5eq6A:
20.95
4z91I-5eq6A:
20.95
4z91J-5eq6A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5eq6 TYPE 4 FIMBRIAL
BIOGENESIS PROTEIN
PILM
(Pseudomonas
aeruginosa) 		4 / 7 THR A 215
THR A 218
THR A 206
LEU A 207
 None
 0.91A 4z91F-5eq6A:
undetectable
4z91G-5eq6A:
undetectable
4z91H-5eq6A:
undetectable
4z91I-5eq6A:
undetectable
4z91J-5eq6A:
undetectable		 4z91F-5eq6A:
20.95
4z91G-5eq6A:
20.95
4z91H-5eq6A:
20.95
4z91I-5eq6A:
20.95
4z91J-5eq6A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 5eq6 TYPE 4 FIMBRIAL
BIOGENESIS PROTEIN
PILM
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 201
GLY A 225
LYS A 247
GLY A 296
ILE A 300
 ANP  A 401 (-3.1A)
ANP  A 401 ( 4.8A)
ANP  A 401 (-3.1A)
ANP  A 401 (-3.2A)
ANP  A 401 (-4.3A)
 0.97A 5aqfA-5eq6A:
18.4		 5aqfA-5eq6A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 5eq6 TYPE 4 FIMBRIAL
BIOGENESIS PROTEIN
PILM
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 201
GLY A 225
LYS A 247
GLY A 296
ILE A 300
 ANP  A 401 (-3.1A)
ANP  A 401 ( 4.8A)
ANP  A 401 (-3.1A)
ANP  A 401 (-3.2A)
ANP  A 401 (-4.3A)
 0.95A 5aqfC-5eq6A:
16.9		 5aqfC-5eq6A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AQY_A_ADNA1389_1
(HEAT SHOCK 70 KDA
PROTEIN 1A)		 5eq6 TYPE 4 FIMBRIAL
BIOGENESIS PROTEIN
PILM
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 201
GLY A 225
LYS A 247
GLY A 296
ILE A 300
 ANP  A 401 (-3.1A)
ANP  A 401 ( 4.8A)
ANP  A 401 (-3.1A)
ANP  A 401 (-3.2A)
ANP  A 401 (-4.3A)
 0.94A 5aqyA-5eq6A:
8.3		 5aqyA-5eq6A:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_F_MFXF2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5eq6 TYPE 4 FIMBRIAL
BIOGENESIS PROTEIN
PILM
(Pseudomonas
aeruginosa) 		4 / 6 SER A 208
ASP A 169
ARG A 351
GLY A 347
 None
 0.90A 5cdqA-5eq6A:
undetectable
5cdqC-5eq6A:
undetectable
5cdqD-5eq6A:
undetectable		 5cdqA-5eq6A:
22.29
5cdqC-5eq6A:
22.29
5cdqD-5eq6A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 5eq6 TYPE 4 FIMBRIAL
BIOGENESIS PROTEIN
PILM
(Pseudomonas
aeruginosa) 		4 / 6 VAL A  67
LYS A  70
ALA A  71
TYR A  39
 None
 0.64A 5i8fA-5eq6A:
undetectable		 5i8fA-5eq6A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_A_ADNA602_1
(LYSINE--TRNA LIGASE)		 5eq6 TYPE 4 FIMBRIAL
BIOGENESIS PROTEIN
PILM
(Pseudomonas
aeruginosa) 		5 / 10 ASN A 150
ARG A 154
ALA A  86
GLU A 171
GLY A  84
 None
None
None
MG  A 402 ( 4.8A)
None
 1.04A 6bniA-5eq6A:
undetectable		 6bniA-5eq6A:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)		 5eq6 TYPE 4 FIMBRIAL
BIOGENESIS PROTEIN
PILM
(Pseudomonas
aeruginosa) 		4 / 6 SER A  19
ALA A 202
THR A 297
ALA A 341
 ANP  A 401 (-2.7A)
ANP  A 401 (-3.2A)
ANP  A 401 (-4.1A)
ANP  A 401 ( 4.0A)
 1.00A 6ma6A-5eq6A:
undetectable		 6ma6A-5eq6A:
10.36