SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5eqj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_B_THAB2_1
(LIVER
CARBOXYLESTERASE I)		 5eqj TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
NON-CATALYTIC
SUBUNIT TRM6
(Saccharomyces
cerevisiae) 		5 / 11 VAL A 373
LEU A 396
LEU A 369
LEU A 225
LEU A 442
 None
 1.23A 1mx1B-5eqjA:
undetectable		 1mx1B-5eqjA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 5eqj TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
NON-CATALYTIC
SUBUNIT TRM6
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 281
PHE A 284
ALA A 285
LEU A 246
 None
 0.86A 1ukbA-5eqjA:
undetectable		 1ukbA-5eqjA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_3
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 5eqj TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
NON-CATALYTIC
SUBUNIT TRM6
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 256
GLY A 258
ASN A 286
VAL A 248
TYR A 249
 None
 1.15A 2nyrB-5eqjA:
3.5		 2nyrB-5eqjA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5eqj TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
NON-CATALYTIC
SUBUNIT TRM6
(Saccharomyces
cerevisiae) 		5 / 12 PRO A  29
VAL A  43
PHE A  51
ILE A   7
ASP A   8
 None
 1.28A 2v95A-5eqjA:
undetectable		 2v95A-5eqjA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_2
(CYTOCHROME P450 2R1)		 5eqj TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
NON-CATALYTIC
SUBUNIT TRM6
(Saccharomyces
cerevisiae) 		3 / 3 MET A 255
VAL A 296
GLU A 253
 None
 0.87A 3c6gA-5eqjA:
undetectable		 3c6gA-5eqjA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4II8_A_010A210_0
(LYSOZYME C)		 5eqj TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
NON-CATALYTIC
SUBUNIT TRM6
(Saccharomyces
cerevisiae) 		4 / 7 GLU A 351
GLN A 348
ASN A 344
ILE A 313
 None
 1.20A 4ii8A-5eqjA:
undetectable		 4ii8A-5eqjA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5eqj TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
NON-CATALYTIC
SUBUNIT TRM6
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 268
ILE A 269
LEU A 372
LEU A 376
 None
 0.90A 4l1wA-5eqjA:
undetectable		 4l1wA-5eqjA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5eqj TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
NON-CATALYTIC
SUBUNIT TRM6
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 252
TYR A 249
PHE A 291
GLY A 258
 None
 0.97A 6hd4B-5eqjA:
undetectable		 6hd4B-5eqjA:
9.22