SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5eqv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
4 / 6 PHE A 187
LYS A 215
LYS A 214
ALA A 213
None
None
PGE  A 407 (-2.7A)
None
1.24A 1hk2A-5eqvA:
undetectable
1hk2A-5eqvA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
3 / 3 ASP A  84
HIS A 125
HIS A  41
FE  A 401 (-2.8A)
PO4  A 405 ( 3.9A)
FE  A 402 ( 3.4A)
0.67A 1oe1A-5eqvA:
undetectable
1oe1A-5eqvA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
3 / 3 ASP A  84
HIS A 125
HIS A  41
FE  A 401 (-2.8A)
PO4  A 405 ( 3.9A)
FE  A 402 ( 3.4A)
0.67A 1oe3A-5eqvA:
undetectable
1oe3A-5eqvA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
4 / 8 PHE A 308
LEU A 227
ILE A 166
ILE A 182
None
0.94A 1sbrA-5eqvA:
undetectable
1sbrA-5eqvA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_D_URFD999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
4 / 4 MET A 262
ALA A 230
TYR A 184
ILE A 231
None
1.50A 1upfD-5eqvA:
undetectable
1upfD-5eqvA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
5 / 12 LEU A 236
LEU A 288
ILE A 291
ALA A 213
ILE A 185
None
1.12A 2h42C-5eqvA:
undetectable
2h42C-5eqvA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
5 / 12 VAL A 150
ILE A 122
ASN A 121
PHE A 127
HIS A 125
None
None
None
None
PO4  A 405 ( 3.9A)
1.26A 2vdyA-5eqvA:
undetectable
2vdyA-5eqvA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
5 / 10 MET A 295
PHE A 263
ALA A 281
LEU A 288
ALA A 293
None
1.36A 2wscB-5eqvA:
undetectable
2wscB-5eqvA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
3 / 3 ASP A  84
HIS A 125
HIS A  41
FE  A 401 (-2.8A)
PO4  A 405 ( 3.9A)
FE  A 402 ( 3.4A)
0.68A 2xxgA-5eqvA:
undetectable
2xxgA-5eqvA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
3 / 3 ASP A  84
HIS A 125
HIS A  41
FE  A 401 (-2.8A)
PO4  A 405 ( 3.9A)
FE  A 402 ( 3.4A)
0.67A 2xxgC-5eqvA:
undetectable
2xxgC-5eqvA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
3 / 3 MET A 112
GLU A 126
ASN A 124
None
None
PO4  A 405 (-2.6A)
1.10A 3a27A-5eqvA:
undetectable
3a27A-5eqvA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
5 / 12 LEU A 303
THR A  63
ALA A  64
LEU A 115
LEU A  40
None
1.15A 3hm1A-5eqvA:
undetectable
3hm1A-5eqvA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
5 / 10 MET A 295
PHE A 263
ALA A 281
LEU A 288
ALA A 293
None
1.32A 3lw5B-5eqvA:
undetectable
3lw5B-5eqvA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
5 / 12 VAL A 150
ILE A 122
ASN A 121
PHE A 127
HIS A 125
None
None
None
None
PO4  A 405 ( 3.9A)
1.20A 4c49A-5eqvA:
undetectable
4c49A-5eqvA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
5 / 12 VAL A 150
ILE A 122
ASN A 121
PHE A 127
HIS A 125
None
None
None
None
PO4  A 405 ( 3.9A)
1.22A 4c49B-5eqvA:
undetectable
4c49B-5eqvA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_F_BEZF501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
4 / 8 ASN A 342
ALA A  64
SER A  65
ARG A  71
None
1.12A 4ijiF-5eqvA:
undetectable
4ijiF-5eqvA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
4 / 7 ASN A 342
ALA A  64
SER A  65
ARG A  71
None
1.11A 4ijiH-5eqvA:
undetectable
4ijiH-5eqvA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_2
(SEPIAPTERIN
REDUCTASE)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
3 / 3 LEU A 349
MET A  45
ASP A 116
None
0.68A 4j7xB-5eqvA:
undetectable
4j7xB-5eqvA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
3 / 3 SER A 248
TYR A 241
PRO A 232
None
PGE  A 407 (-3.5A)
None
0.96A 4kanA-5eqvA:
2.4
4kanA-5eqvA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
3 / 3 SER A 248
TYR A 241
PRO A 232
None
PGE  A 407 (-3.5A)
None
0.97A 4lbgB-5eqvA:
undetectable
4lbgB-5eqvA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NPT_A_017A401_1
(PROTEASE)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
5 / 9 ALA A 260
ILE A 182
GLY A 183
ILE A 185
VAL A 306
None
0.98A 4nptA-5eqvA:
undetectable
4nptA-5eqvA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_D_ACTD201_0
(RETINOL-BINDING
PROTEIN 2)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
3 / 3 ASP A 172
HIS A 178
LYS A 171
None
0.99A 4qzuD-5eqvA:
undetectable
4qzuD-5eqvA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
4 / 6 TYR A 145
GLY A 123
GLU A 126
ASP A  39
None
None
None
FE  A 402 (-3.1A)
1.32A 5emlA-5eqvA:
undetectable
5emlA-5eqvA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
4 / 7 LEU A  40
THR A  37
ILE A  67
LEU A  35
None
1.01A 5fxtA-5eqvA:
undetectable
5fxtA-5eqvA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
5 / 10 TYR A 117
ILE A  67
LEU A  35
VAL A 294
PRO A 271
None
1.16A 5ienB-5eqvA:
0.4
5ienB-5eqvA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
5 / 12 ASP A 301
ILE A 329
GLU A 341
HIS A 353
GLY A  59
None
1.06A 5k7uA-5eqvA:
undetectable
5k7uA-5eqvA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
5 / 6 ASP A  84
ASP A  39
HIS A  41
HIS A 267
HIS A 233
FE  A 401 (-2.8A)
FE  A 402 (-3.1A)
FE  A 402 ( 3.4A)
FE  A 402 ( 3.4A)
FE  A 401 (-3.4A)
1.12A 5ncdB-5eqvA:
undetectable
5ncdC-5eqvA:
undetectable
5ncdB-5eqvA:
24.22
5ncdC-5eqvA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
4 / 4 ASP A  84
HIS A 233
HIS A 265
HIS A 125
FE  A 401 (-2.8A)
FE  A 401 (-3.4A)
FE  A 401 ( 3.3A)
PO4  A 405 ( 3.9A)
1.47A 5ncdD-5eqvA:
undetectable
5ncdD-5eqvA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
5 / 6 ASP A  84
ASP A  39
HIS A  41
HIS A 267
HIS A 233
FE  A 401 (-2.8A)
FE  A 402 (-3.1A)
FE  A 402 ( 3.4A)
FE  A 402 ( 3.4A)
FE  A 401 (-3.4A)
1.10A 5nelA-5eqvA:
undetectable
5nelD-5eqvA:
undetectable
5nelA-5eqvA:
24.22
5nelD-5eqvA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
4 / 6 ASP A  84
HIS A  41
HIS A 267
HIS A 233
FE  A 401 (-2.8A)
FE  A 402 ( 3.4A)
FE  A 402 ( 3.4A)
FE  A 401 (-3.4A)
1.04A 5nelB-5eqvA:
undetectable
5nelC-5eqvA:
undetectable
5nelB-5eqvA:
24.22
5nelC-5eqvA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC607_0
(ALPHA-AMYLASE)
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia
pestis)
4 / 6 GLY A 297
ASP A 274
GLY A 264
GLY A 235
None
0.77A 6ag0C-5eqvA:
2.2
6ag0C-5eqvA:
15.09