SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5eqw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A15_A_NCAA1001_0
(HYPOTHETICAL PROTEIN
RV0760C)		 5eqw PUTATIVE MAJOR COAT
PROTEIN
(Acidianus
tailed
spindle
virus) 		5 / 11 VAL A  15
ILE A  18
LEU A  19
LEU A 111
LEU A 108
 None
 1.22A 2a15A-5eqwA:
undetectable		 2a15A-5eqwA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_H_TOPH200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5eqw PUTATIVE MAJOR COAT
PROTEIN
(Acidianus
tailed
spindle
virus) 		5 / 9 ALA A  37
GLU A  40
VAL A  55
ILE A  62
LEU A 108
 None
 1.19A 3fl9H-5eqwA:
undetectable		 3fl9H-5eqwA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 5eqw PUTATIVE MAJOR COAT
PROTEIN
(Acidianus
tailed
spindle
virus) 		4 / 5 ASN A  88
ALA A  89
PRO A  86
TYR A  79
 None
 1.30A 3twpD-5eqwA:
undetectable		 3twpD-5eqwA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5V_A_ACTA511_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5eqw PUTATIVE MAJOR COAT
PROTEIN
(Acidianus
tailed
spindle
virus) 		4 / 4 ASN A  25
PHE A  82
SER A  84
GLN A 101
 None
 1.50A 3v5vA-5eqwA:
undetectable		 3v5vA-5eqwA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1006_1
(SERUM ALBUMIN)		 5eqw PUTATIVE MAJOR COAT
PROTEIN
(Acidianus
tailed
spindle
virus) 		4 / 7 ILE A  18
LEU A  19
GLY A  13
LYS A  10
 None
 1.02A 4z69A-5eqwA:
undetectable		 4z69A-5eqwA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_A_ZITA501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 5eqw PUTATIVE MAJOR COAT
PROTEIN
(Acidianus
tailed
spindle
virus) 		4 / 7 GLU A 125
ALA A  12
GLY A  14
TYR A  11
 None
 0.91A 5uxdA-5eqwA:
2.0		 5uxdA-5eqwA:
15.61