SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5eqx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1321_0
(CHLOROPEROXIDASE)		 5eqx DESMOGLEIN-3
(Homo
sapiens) 		4 / 5 LEU A 386
PHE A 341
VAL A 417
ALA A 415
 None
 1.07A 2cizA-5eqxA:
undetectable		 2cizA-5eqxA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_A_KKKA413_1
(FLAVOHEMOGLOBIN)		 5eqx DESMOGLEIN-3
(Homo
sapiens) 		4 / 8 ILE A  34
TYR A  36
GLN A  29
ALA A  30
 None
 0.82A 3ozwA-5eqxA:
undetectable		 3ozwA-5eqxA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5eqx DESMOGLEIN-3
(Homo
sapiens) 		4 / 6 VAL A 294
VAL A 325
ILE A 227
LEU A 280
 None
 0.97A 4l1wB-5eqxA:
undetectable		 4l1wB-5eqxA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5eqx DESMOGLEIN-3
(Homo
sapiens) 		3 / 3 SER A 297
ALA A 299
VAL A 300
 None
 0.51A 4x1iA-5eqxA:
undetectable		 4x1iA-5eqxA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 5eqx DESMOGLEIN-3
(Homo
sapiens) 		3 / 4 ARG A  10
GLY A  12
GLU A  13
 None
 0.58A 4z2dB-5eqxA:
undetectable
4z2dC-5eqxA:
undetectable		 4z2dB-5eqxA:
22.84
4z2dC-5eqxA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 5eqx DESMOGLEIN-3
(Homo
sapiens) 		3 / 3 TYR A 433
THR A 412
THR A 340
 None
 0.67A 5aoxB-5eqxA:
undetectable		 5aoxB-5eqxA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 5eqx DESMOGLEIN-3
(Homo
sapiens) 		3 / 3 TYR A 433
THR A 412
THR A 340
 None
 0.60A 5aoxE-5eqxA:
undetectable		 5aoxE-5eqxA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5eqx DESMOGLEIN-3
(Homo
sapiens) 		3 / 3 SER A 297
ALA A 299
VAL A 300
 None
 0.53A 5eypA-5eqxA:
undetectable		 5eypA-5eqxA:
22.49