SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5er3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_D_DVAD6_0
(MINI-GRAMICIDIN A)		 5er3 SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN
(Rhodopirellula
baltica) 		3 / 3 TRP A  91
ALA A  70
VAL A 335
 None
 0.89A 1kqeB-5er3A:
undetectable
1kqeD-5er3A:
undetectable		 1kqeB-5er3A:
4.57
1kqeD-5er3A:
4.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 5er3 SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN
(Rhodopirellula
baltica) 		4 / 5 LEU A  90
VAL A  88
ALA A  85
CYH A  86
 None
 1.14A 1mz9D-5er3A:
undetectable		 1mz9D-5er3A:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 5er3 SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN
(Rhodopirellula
baltica) 		5 / 12 GLU A 233
TYR A 140
TYR A 144
VAL A 147
VAL A 239
 None
GOL  A 402 (-4.8A)
None
None
None
 1.43A 2rguA-5er3A:
2.6		 2rguA-5er3A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_B_VDNB1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5er3 SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN
(Rhodopirellula
baltica) 		5 / 11 ILE A 350
ALA A 324
ILE A 325
VAL A 114
ILE A  98
 None
 1.15A 3b2rB-5er3A:
undetectable		 3b2rB-5er3A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 5er3 SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN
(Rhodopirellula
baltica) 		5 / 12 GLU A 233
TYR A 140
TYR A 144
VAL A 147
VAL A 239
 None
GOL  A 402 (-4.8A)
None
None
None
 1.42A 3g0bB-5er3A:
undetectable		 3g0bB-5er3A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 5er3 SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN
(Rhodopirellula
baltica) 		5 / 12 GLU A 233
TYR A 140
TYR A 144
VAL A 147
VAL A 239
 None
GOL  A 402 (-4.8A)
None
None
None
 1.41A 3g0bC-5er3A:
undetectable		 3g0bC-5er3A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 5er3 SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN
(Rhodopirellula
baltica) 		5 / 12 GLU A 233
TYR A 140
TYR A 144
VAL A 147
VAL A 239
 None
GOL  A 402 (-4.8A)
None
None
None
 1.42A 3g0bD-5er3A:
undetectable		 3g0bD-5er3A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 5er3 SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN
(Rhodopirellula
baltica) 		5 / 12 GLU A 233
TYR A 140
TYR A 144
VAL A 147
VAL A 239
 None
GOL  A 402 (-4.8A)
None
None
None
 1.43A 3w2tA-5er3A:
undetectable		 3w2tA-5er3A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 5er3 SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN
(Rhodopirellula
baltica) 		5 / 12 LEU A  99
GLY A 109
LEU A  78
THR A  76
THR A  77
 None
 0.85A 4m2vA-5er3A:
undetectable		 4m2vA-5er3A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_B_BEZB1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 5er3 SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN
(Rhodopirellula
baltica) 		4 / 6 GLY A 125
THR A 122
SER A 130
VAL A 131
 None
 1.10A 5ewuB-5er3A:
2.2		 5ewuB-5er3A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA511_1
(PROTON-GATED ION
CHANNEL)		 5er3 SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN
(Rhodopirellula
baltica) 		5 / 8 ILE A 281
PRO A 271
ILE A 213
ALA A 268
ILE A 267
 None
 1.01A 5mvmA-5er3A:
undetectable
5mvmB-5er3A:
undetectable		 5mvmA-5er3A:
11.08
5mvmB-5er3A:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW4_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 5er3 SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN
(Rhodopirellula
baltica) 		5 / 9 SER A 309
GLY A 314
ALA A 313
GLY A 349
GLU A 345
 None
 1.19A 5vw4A-5er3A:
2.4		 5vw4A-5er3A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_A_SAMA401_0
(O-METHYLTRANSFERASE)		 5er3 SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN
(Rhodopirellula
baltica) 		5 / 12 ASP A 117
GLY A  89
GLY A 115
ARG A 346
SER A 347
 None
 1.23A 6clxA-5er3A:
3.1		 6clxA-5er3A:
24.41