SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5er7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E7B_A_HLTA4002_1 (SERUM ALBUMIN)	5er7	GAP JUNCTION BETA-2 PROTEIN (Homo sapiens)	4 / 4	ARG B 75 ALA B 78 ALA B 40 GLU B 47	None None None CA B 301 (-2.3A)	1.10A	1e7bA-5er7B: undetectable	1e7bA-5er7B: 15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EZ7_A_DHIA301_0 (CARBONIC ANHYDRASE 2)	5er7	GAP JUNCTION BETA-2 PROTEIN (Homo sapiens)	4 / 6	TRP B 77 HIS B 73 GLN B 164 THR B 192	None	1.28A	2ez7A-5er7B: undetectable	2ez7A-5er7B: 18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_C_SVRC505_2 (PHOSPHOLIPASE A2)	5er7	GAP JUNCTION BETA-2 PROTEIN (Homo sapiens)	4 / 5	VAL B 38 VAL B 37 PHE B 194 ARG B 75	None	1.12A	3bjwH-5er7B: undetectable	3bjwH-5er7B: 18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_C_SVRC507_2 (PHOSPHOLIPASE A2)	5er7	GAP JUNCTION BETA-2 PROTEIN (Homo sapiens)	4 / 6	VAL B 38 VAL B 37 PHE B 194 ARG B 75	None	0.96A	3bjwF-5er7B: 1.4	3bjwF-5er7B: 18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D4S_A_TIMA401_2 (BETA-2 ADRENERGIC RECEPTOR/T4-LYSOZYME CHIMERA)	5er7	GAP JUNCTION BETA-2 PROTEIN (Homo sapiens)	3 / 3	THR B 189 SER B 162 PHE B 69	None	0.67A	3d4sA-5er7B: 2.1	3d4sA-5er7B: 20.57

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1E7B_A_HLTA4002_1","SERUM ALBUMIN","5er7","GAP JUNCTION BETA-2 PROTEIN","Homo sapiens",4,"ARG B  75;ALA B  78;ALA B  40;GLU B  47","None;None;None; CA B 301 (-2.3A)","1.10A","1e7bA-5er7B:undetectable","1e7bA-5er7B:15.45"],["2EZ7_A_DHIA301_0","CARBONIC ANHYDRASE 2","5er7","GAP JUNCTION BETA-2 PROTEIN","Homo sapiens",4,"TRP B  77;HIS B  73;GLN B 164;THR B 192","None","1.28A","2ez7A-5er7B:undetectable","2ez7A-5er7B:18.96"],["3BJW_C_SVRC505_2","PHOSPHOLIPASE A2;PHOSPHOLIPASE A2","5er7","GAP JUNCTION BETA-2 PROTEIN","Homo sapiens",4,"VAL B  38;VAL B  37;PHE B 194;ARG B  75","None","1.12A","3bjwH-5er7B:undetectable","3bjwH-5er7B:18.42"],["3BJW_C_SVRC507_2","PHOSPHOLIPASE A2;PHOSPHOLIPASE A2","5er7","GAP JUNCTION BETA-2 PROTEIN","Homo sapiens",4,"VAL B  38;VAL B  37;PHE B 194;ARG B  75","None","0.96A","3bjwF-5er7B:1.4","3bjwF-5er7B:18.42"],["3D4S_A_TIMA401_2","BETA-2 ADRENERGIC RECEPTOR\/T4-LYSOZYME CHIMERA","5er7","GAP JUNCTION BETA-2 PROTEIN","Homo sapiens",3,"THR B 189;SER B 162;PHE B  69","None","0.67A","3d4sA-5er7B:2.1","3d4sA-5er7B:20.57"]]