SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5esc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7H_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 5esc HUPZ
(Streptococcus
sp.
'group
A') 		3 / 3 ARG A  35
THR A  41
TRP A  37
 None
 0.97A 4d7hA-5escA:
undetectable		 4d7hA-5escA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 5esc HUPZ
(Streptococcus
sp.
'group
A') 		4 / 6 MET A 101
ILE A  62
ILE A  64
VAL A  17
 None
 1.00A 4olmA-5escA:
undetectable		 4olmA-5escA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UG5_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 5esc HUPZ
(Streptococcus
sp.
'group
A') 		3 / 3 ARG A  35
THR A  41
TRP A  37
 None
 0.94A 4ug5A-5escA:
undetectable		 4ug5A-5escA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGL_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 5esc HUPZ
(Streptococcus
sp.
'group
A') 		3 / 3 ARG A  35
THR A  41
TRP A  37
 None
 0.94A 4uglA-5escA:
undetectable		 4uglA-5escA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6C_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 5esc HUPZ
(Streptococcus
sp.
'group
A') 		3 / 3 ARG A  35
THR A  41
TRP A  37
 None
 0.94A 5g6cA-5escA:
undetectable		 5g6cA-5escA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_2
(PROTEASE PR5-DRV)		 5esc HUPZ
(Streptococcus
sp.
'group
A') 		4 / 8 GLY A  60
VAL A  17
GLY A 108
ILE A 109
 None
 0.56A 5kr1B-5escA:
undetectable		 5kr1B-5escA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5esc HUPZ
(Streptococcus
sp.
'group
A') 		5 / 10 ILE A  64
ILE A 110
VAL A  17
THR A  19
ILE A  56
 None
 1.29A 5lg3G-5escA:
undetectable		 5lg3G-5escA:
18.39