SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5esy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF211_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5esy SAL1 PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 7 LEU A 275
PHE A 228
LEU A 336
SER A 217
 None
 1.06A 1wrlE-5esyA:
undetectable
1wrlF-5esyA:
undetectable		 1wrlE-5esyA:
13.54
1wrlF-5esyA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)		 5esy SAL1 PHOSPHATASE
(Arabidopsis
thaliana) 		5 / 12 PHE A 192
VAL A 296
SER A 267
CYH A 167
LEU A 311
 None
 1.25A 2hc4A-5esyA:
undetectable		 2hc4A-5esyA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_A_NCAA302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 5esy SAL1 PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 8 TYR A 274
ASP A 137
ALA A 149
TYR A 263
 None
 0.85A 3rodA-5esyA:
undetectable		 3rodA-5esyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 5esy SAL1 PHOSPHATASE
(Arabidopsis
thaliana) 		5 / 12 LEU A 275
SER A 241
ILE A 273
ALA A 225
LEU A 248
 None
 1.28A 3vw1B-5esyA:
undetectable		 3vw1B-5esyA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 5esy SAL1 PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 7 THR A 297
LEU A 165
VAL A 327
VAL A 303
 None
 0.94A 4cp4A-5esyA:
undetectable		 4cp4A-5esyA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_0
(METHYLTRANSFERASE
NSUN4)		 5esy SAL1 PHOSPHATASE
(Arabidopsis
thaliana) 		5 / 12 GLY A 124
GLY A 125
LEU A 152
GLY A 163
LEU A 162
 None
 0.89A 4fp9A-5esyA:
undetectable		 4fp9A-5esyA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_0
(METHYLTRANSFERASE
NSUN4)		 5esy SAL1 PHOSPHATASE
(Arabidopsis
thaliana) 		5 / 12 GLY A 124
GLY A 125
LEU A 152
GLY A 163
LEU A 162
 None
 0.90A 4fp9C-5esyA:
undetectable		 4fp9C-5esyA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_0
(METHYLTRANSFERASE
NSUN4)		 5esy SAL1 PHOSPHATASE
(Arabidopsis
thaliana) 		5 / 12 GLY A 124
GLY A 125
LEU A 152
GLY A 163
LEU A 162
 None
 0.89A 4fp9D-5esyA:
undetectable		 4fp9D-5esyA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_0
(METHYLTRANSFERASE
NSUN4)		 5esy SAL1 PHOSPHATASE
(Arabidopsis
thaliana) 		5 / 12 GLY A 124
GLY A 125
LEU A 152
GLY A 163
LEU A 162
 None
 0.89A 4fp9F-5esyA:
undetectable		 4fp9F-5esyA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_0
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 5esy SAL1 PHOSPHATASE
(Arabidopsis
thaliana) 		5 / 12 GLY A 124
GLY A 125
LEU A 152
GLY A 163
LEU A 162
 None
 0.93A 4fzvA-5esyA:
undetectable		 4fzvA-5esyA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5esy SAL1 PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 5 ILE A 325
ASP A 320
GLU A 284
VAL A 290
 None
 1.18A 4nkxC-5esyA:
undetectable		 4nkxC-5esyA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 5esy SAL1 PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 7 GLY A 300
ALA A 299
GLU A 298
THR A 200
 None
 0.83A 4r1zB-5esyA:
undetectable		 4r1zB-5esyA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 5esy SAL1 PHOSPHATASE
(Arabidopsis
thaliana) 		5 / 12 LEU A 152
ALA A 151
LEU A 165
LEU A 191
LEU A 205
 None
 1.05A 5toaA-5esyA:
undetectable		 5toaA-5esyA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5esy SAL1 PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 5 GLN A  22
VAL A  24
PRO A 168
THR A  43
 None
 1.30A 6cduA-5esyA:
1.2
6cduB-5esyA:
undetectable		 6cduA-5esyA:
20.82
6cduB-5esyA:
20.82