SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5esz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5esz 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE,ENVELOPE
GLYCOPROTEIN GP160
(Haemophilus
influenzae;
Human
immunodeficiency
virus
1) 		5 / 11 ILE C 305
VAL C 204
ALA C 205
ILE C 255
PHE C 119
 None
 1.16A 1uduA-5eszC:
undetectable		 1uduA-5eszC:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5esz 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE,ENVELOPE
GLYCOPROTEIN GP160
(Haemophilus
influenzae;
Human
immunodeficiency
virus
1) 		5 / 12 GLY C 118
CYH C 307
ASP C 211
ALA C 208
ALA C 205
 None
 1.09A 2br4A-5eszC:
undetectable		 2br4A-5eszC:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5esz 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE,ENVELOPE
GLYCOPROTEIN GP160
(Haemophilus
influenzae;
Human
immunodeficiency
virus
1) 		5 / 12 GLY C 118
CYH C 307
ASP C 211
ALA C 208
ALA C 205
 None
 1.09A 2br4B-5eszC:
undetectable		 2br4B-5eszC:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 5esz 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE,ENVELOPE
GLYCOPROTEIN GP160
(Haemophilus
influenzae;
Human
immunodeficiency
virus
1) 		5 / 11 ARG C 315
ILE C 213
LEU C 209
ARG C 114
GLY C 116
 None
 1.33A 2bxmA-5eszC:
undetectable		 2bxmA-5eszC:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_E_LLLE301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5esz 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE,ENVELOPE
GLYCOPROTEIN GP160
(Haemophilus
influenzae;
Human
immunodeficiency
virus
1) 		4 / 7 ASP C 231
ARG C 237
ASP C 278
GLU C 277
 None
 1.37A 6mn5E-5eszC:
undetectable		 6mn5E-5eszC:
17.74