SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5eu0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZF_A_TMQA170_1
(DIHYDROFOLATE
REDUCTASE)		 5eu0 ANTITOXIN 1
BARTONELLA EFFECTOR
PROTEIN (BEP)
SUBSTRATE OF VIRB
T4SS
(Bartonella
rochalimae) 		5 / 12 LEU A  82
ALA A  55
HIS B  38
PHE A  46
THR A  58
 None
 1.07A 1bzfA-5eu0A:
undetectable		 1bzfA-5eu0A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_A_NCAA700_0
(EXOTOXIN A)		 5eu0 ANTITOXIN 1
(Bartonella
rochalimae) 		4 / 7 GLY B  47
ALA B  49
TYR B  48
GLU B  15
 None
 0.92A 1dmaA-5eu0B:
undetectable		 1dmaA-5eu0B:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZ4_A_BEZA784_0
(MALT REGULATORY
PROTEIN)		 5eu0 BARTONELLA EFFECTOR
PROTEIN (BEP)
SUBSTRATE OF VIRB
T4SS
(Bartonella
rochalimae) 		4 / 6 HIS A 157
LEU A 147
LEU A 150
PRO A 151
 None
 0.64A 1hz4A-5eu0A:
undetectable		 1hz4A-5eu0A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5eu0 BARTONELLA EFFECTOR
PROTEIN (BEP)
SUBSTRATE OF VIRB
T4SS
ANTITOXIN 1
(Bartonella
rochalimae;
Bartonella
rochalimae) 		3 / 3 HIS B  38
ASP A  53
ASN A  60
 None
 0.75A 1wg8B-5eu0B:
undetectable		 1wg8B-5eu0B:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 5eu0 BARTONELLA EFFECTOR
PROTEIN (BEP)
SUBSTRATE OF VIRB
T4SS
(Bartonella
rochalimae) 		4 / 6 ILE A 162
LEU A 166
LEU A 141
ASP A 138
 None
 1.01A 2rlfA-5eu0A:
undetectable
2rlfD-5eu0A:
undetectable		 2rlfA-5eu0A:
17.07
2rlfD-5eu0A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 5eu0 BARTONELLA EFFECTOR
PROTEIN (BEP)
SUBSTRATE OF VIRB
T4SS
(Bartonella
rochalimae) 		4 / 8 GLY A 133
ASN A 136
ARG A 139
PRO A 171
 None
None
SO4  A 302 (-2.7A)
None
 0.99A 4j4vC-5eu0A:
1.2		 4j4vC-5eu0A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5eu0 BARTONELLA EFFECTOR
PROTEIN (BEP)
SUBSTRATE OF VIRB
T4SS
(Bartonella
rochalimae) 		5 / 12 ILE A 156
MET A 205
VAL A 208
GLY A 177
PHE A 183
 None
None
None
SO4  A 301 (-3.7A)
None
 1.15A 5igiA-5eu0A:
undetectable		 5igiA-5eu0A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_D_CCSD14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)		 5eu0 BARTONELLA EFFECTOR
PROTEIN (BEP)
SUBSTRATE OF VIRB
T4SS
(Bartonella
rochalimae) 		5 / 12 PHE A 124
LEU A 166
GLY A 133
VAL A 130
ARG A  94
 None
 1.21A 5o4yD-5eu0A:
undetectable
5o4yE-5eu0A:
undetectable		 5o4yD-5eu0A:
16.98
5o4yE-5eu0A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA819_0
(GEPHYRIN)		 5eu0 ANTITOXIN 1
(Bartonella
rochalimae) 		3 / 3 ARG B  19
GLY B  51
GLU B  52
 None
 0.51A 6fgdA-5eu0B:
undetectable		 6fgdA-5eu0B:
10.96