SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5euf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FAP_A_RAPA108_2
(FK506-BINDING
PROTEIN
FRAP)		 5euf PROTEASE
(Helicobacter
pylori) 		4 / 8 PHE A 324
GLY A 302
TYR A 172
PHE A 175
 None
 0.75A 1fapB-5eufA:
undetectable		 1fapB-5eufA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5euf PROTEASE
(Helicobacter
pylori) 		5 / 9 MET A  71
PHE A 192
SER A  74
GLY A  75
TRP A 187
 None
 1.36A 1jb0A-5eufA:
undetectable		 1jb0A-5eufA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5euf PROTEASE
(Helicobacter
pylori) 		5 / 12 LEU A 300
LEU A 297
ALA A 296
LEU A 419
VAL A 421
 None
 1.04A 1s9pC-5eufA:
undetectable		 1s9pC-5eufA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_2
(RETINOIC ACID
RECEPTOR, BETA)		 5euf PROTEASE
(Helicobacter
pylori) 		3 / 3 LEU A 133
PHE A  96
ARG A 117
 None
 0.85A 1xdkF-5eufA:
undetectable		 1xdkF-5eufA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 5euf PROTEASE
(Helicobacter
pylori) 		5 / 12 ALA A 109
HIS A  82
GLU A  81
HIS A  78
GLU A 158
 None
ZN  A 502 (-4.4A)
ZN  A 502 ( 4.2A)
ZN  A 502 (-3.3A)
ZN  A 502 (-2.6A)
 0.72A 2c6nA-5eufA:
undetectable		 2c6nA-5eufA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 5euf PROTEASE
(Helicobacter
pylori) 		4 / 7 TYR A 182
HIS A 183
PRO A 184
TYR A 253
 None
 1.00A 2ombC-5eufA:
undetectable
2ombD-5eufA:
undetectable		 2ombC-5eufA:
19.67
2ombD-5eufA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5euf PROTEASE
(Helicobacter
pylori) 		4 / 7 GLY A 280
THR A 438
PHE A 176
PHE A 113
 None
 1.20A 2qx4A-5eufA:
undetectable
2qx4B-5eufA:
undetectable		 2qx4A-5eufA:
21.17
2qx4B-5eufA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5euf PROTEASE
(Helicobacter
pylori) 		3 / 3 LEU A  80
TRP A 187
TYR A 211
 None
 0.97A 3aicA-5eufA:
undetectable		 3aicA-5eufA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5euf PROTEASE
(Helicobacter
pylori) 		3 / 3 LEU A  80
TRP A 187
TYR A 211
 None
 0.97A 3aicB-5eufA:
undetectable		 3aicB-5eufA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5euf PROTEASE
(Helicobacter
pylori) 		3 / 3 LEU A  80
TRP A 187
TYR A 211
 None
 0.97A 3aicE-5eufA:
undetectable		 3aicE-5eufA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5euf PROTEASE
(Helicobacter
pylori) 		3 / 3 LEU A  80
TRP A 187
TYR A 211
 None
 0.98A 3aicF-5eufA:
undetectable		 3aicF-5eufA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5euf PROTEASE
(Helicobacter
pylori) 		3 / 3 LEU A  80
TRP A 187
TYR A 211
 None
 0.92A 3aicG-5eufA:
undetectable		 3aicG-5eufA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5euf PROTEASE
(Helicobacter
pylori) 		3 / 3 LEU A  80
TRP A 187
TYR A 211
 None
 0.96A 3aicH-5eufA:
undetectable		 3aicH-5eufA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 5euf PROTEASE
(Helicobacter
pylori) 		5 / 12 LEU A 330
VAL A 283
PHE A 432
LEU A 362
LEU A 424
 None
 1.26A 3b0wB-5eufA:
undetectable		 3b0wB-5eufA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 5euf PROTEASE
(Helicobacter
pylori) 		4 / 8 GLU A 303
PHE A 416
GLN A 379
ASP A 382
 None
 1.20A 3mjrD-5eufA:
undetectable		 3mjrD-5eufA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_A_PQNA847_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5euf PROTEASE
(Helicobacter
pylori) 		5 / 9 MET A  71
PHE A 192
SER A  74
GLY A  75
TRP A 187
 None
 1.37A 3pcqA-5eufA:
undetectable		 3pcqA-5eufA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5euf PROTEASE
(Helicobacter
pylori) 		4 / 6 TYR A 281
LEU A 359
VAL A 356
VAL A 277
 None
 1.11A 4g3rA-5eufA:
undetectable		 4g3rA-5eufA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5euf PROTEASE
(Helicobacter
pylori) 		4 / 6 TYR A 281
LEU A 359
VAL A 356
VAL A 277
 None
 1.08A 4l4cA-5eufA:
undetectable		 4l4cA-5eufA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 5euf PROTEASE
(Helicobacter
pylori) 		4 / 8 PHE A 119
SER A 110
ASP A 114
TYR A 400
 None
 1.32A 4qb9D-5eufA:
undetectable		 4qb9D-5eufA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_A_QI9A602_0
(CYTOCHROME P450 2D6)		 5euf PROTEASE
(Helicobacter
pylori) 		5 / 9 PHE A 238
LEU A  38
VAL A  58
VAL A 219
LEU A 127
 None
 1.20A 4wnvA-5eufA:
0.2		 4wnvA-5eufA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 5euf PROTEASE
(Helicobacter
pylori) 		4 / 8 PHE A 324
GLY A 302
TYR A 172
PHE A 175
 None
 0.71A 5flcB-5eufA:
undetectable		 5flcB-5eufA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 5euf PROTEASE
(Helicobacter
pylori) 		4 / 8 PHE A 324
GLY A 302
TYR A 172
PHE A 175
 None
 0.71A 5flcF-5eufA:
undetectable		 5flcF-5eufA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A220_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 5euf PROTEASE
(Helicobacter
pylori) 		5 / 9 LEU A 141
HIS A 208
TYR A  62
TYR A 212
THR A 116
 None
 1.32A 5mxbA-5eufA:
1.5		 5mxbA-5eufA:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5euf PROTEASE
(Helicobacter
pylori) 		3 / 3 ASP A 392
ASN A 386
ASP A 382
 None
 0.78A 5vopB-5eufA:
undetectable		 5vopB-5eufA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5euf PROTEASE
(Helicobacter
pylori) 		5 / 10 MET A  71
PHE A 192
SER A  74
GLY A  75
TRP A 187
 None
 1.28A 5zjiA-5eufA:
undetectable
5zjiJ-5eufA:
undetectable		 5zjiA-5eufA:
10.24
5zjiJ-5eufA:
7.75