SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5euh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQW_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN)		 5euh PUTATIVE GGDEF
DOMAIN MEMBRANE
PROTEIN
(Pseudomonas
fluorescens) 		5 / 12 ILE A 438
THR A 345
ARG A 409
VAL A 347
ILE A 376
 C2E  A 601 (-4.8A)
None
C2E  A 601 ( 4.0A)
None
None
 1.16A 1kqwA-5euhA:
undetectable		 1kqwA-5euhA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 5euh PUTATIVE GGDEF
DOMAIN MEMBRANE
PROTEIN
(Pseudomonas
fluorescens) 		5 / 10 ALA A 401
VAL A 415
ILE A 438
LEU A 427
THR A 345
 None
None
C2E  A 601 (-4.8A)
C2E  A 601 ( 4.4A)
None
 1.11A 3jw5B-5euhA:
undetectable		 3jw5B-5euhA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDC_A_ASDA404_1
(3-KETOSTEROID
9ALPHA-HYDROXYLASE
OXYGENASE)		 5euh PUTATIVE GGDEF
DOMAIN MEMBRANE
PROTEIN
(Pseudomonas
fluorescens) 		5 / 12 LEU A 397
ALA A 343
ASP A 342
ASN A 349
PHE A 423
 None
 1.41A 4qdcA-5euhA:
undetectable		 4qdcA-5euhA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 5euh PUTATIVE GGDEF
DOMAIN MEMBRANE
PROTEIN
(Pseudomonas
fluorescens) 		4 / 4 VAL A 498
ILE A 376
ASN A 407
VAL A 446
 None
 1.07A 5ajqA-5euhA:
undetectable		 5ajqA-5euhA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GLM_A_ACTA613_0
(GLYCOSIDE HYDROLASE
FAMILY 43)		 5euh PUTATIVE GGDEF
DOMAIN MEMBRANE
PROTEIN
(Pseudomonas
fluorescens) 		3 / 3 ASP A 354
SER A 424
TYR A 418
 None
 0.85A 5glmA-5euhA:
undetectable		 5glmA-5euhA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_0
(METHYLTRANSFERASE)		 5euh PUTATIVE GGDEF
DOMAIN MEMBRANE
PROTEIN
(Pseudomonas
fluorescens) 		5 / 12 ALA A 396
ILE A 463
GLU A 447
ALA A 439
PHE A 423
 None
 1.02A 5n5dB-5euhA:
undetectable		 5n5dB-5euhA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA819_0
(GEPHYRIN)		 5euh PUTATIVE GGDEF
DOMAIN MEMBRANE
PROTEIN
(Pseudomonas
fluorescens) 		3 / 3 ARG A 417
GLY A 420
GLU A 421
 None
 0.62A 6fgdA-5euhA:
undetectable		 6fgdA-5euhA:
19.16