SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5eul'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
THR Y 412
None
1.28A 1c9sA-5eulY:
undetectable
1c9sK-5eulY:
undetectable
1c9sA-5eulY:
10.61
1c9sK-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.29A 1c9sA-5eulY:
undetectable
1c9sB-5eulY:
undetectable
1c9sA-5eulY:
10.61
1c9sB-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.26A 1c9sB-5eulY:
undetectable
1c9sC-5eulY:
undetectable
1c9sB-5eulY:
10.61
1c9sC-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 1c9sC-5eulY:
undetectable
1c9sD-5eulY:
undetectable
1c9sC-5eulY:
10.61
1c9sD-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 1c9sD-5eulY:
undetectable
1c9sE-5eulY:
undetectable
1c9sD-5eulY:
10.61
1c9sE-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.27A 1c9sE-5eulY:
undetectable
1c9sF-5eulY:
undetectable
1c9sE-5eulY:
10.61
1c9sF-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.26A 1c9sF-5eulY:
undetectable
1c9sG-5eulY:
undetectable
1c9sF-5eulY:
10.61
1c9sG-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.27A 1c9sG-5eulY:
undetectable
1c9sH-5eulY:
undetectable
1c9sG-5eulY:
10.61
1c9sH-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.27A 1c9sH-5eulY:
undetectable
1c9sI-5eulY:
undetectable
1c9sH-5eulY:
10.61
1c9sI-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.27A 1c9sJ-5eulY:
undetectable
1c9sK-5eulY:
undetectable
1c9sJ-5eulY:
10.61
1c9sK-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
THR Y 412
None
1.26A 1gtfA-5eulY:
undetectable
1gtfK-5eulY:
undetectable
1gtfA-5eulY:
10.61
1gtfK-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.27A 1gtfA-5eulY:
undetectable
1gtfB-5eulY:
undetectable
1gtfA-5eulY:
10.61
1gtfB-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.29A 1gtfB-5eulY:
undetectable
1gtfC-5eulY:
undetectable
1gtfB-5eulY:
10.61
1gtfC-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.30A 1gtfC-5eulY:
undetectable
1gtfD-5eulY:
undetectable
1gtfC-5eulY:
10.61
1gtfD-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.26A 1gtfE-5eulY:
undetectable
1gtfF-5eulY:
undetectable
1gtfE-5eulY:
10.61
1gtfF-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 1gtfF-5eulY:
undetectable
1gtfG-5eulY:
undetectable
1gtfF-5eulY:
10.61
1gtfG-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.27A 1gtfG-5eulY:
undetectable
1gtfH-5eulY:
undetectable
1gtfG-5eulY:
10.61
1gtfH-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.25A 1gtfH-5eulY:
undetectable
1gtfI-5eulY:
undetectable
1gtfH-5eulY:
10.61
1gtfI-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 1gtfI-5eulY:
undetectable
1gtfJ-5eulY:
undetectable
1gtfI-5eulY:
10.61
1gtfJ-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.30A 1gtfL-5eulY:
undetectable
1gtfV-5eulY:
undetectable
1gtfL-5eulY:
10.61
1gtfV-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.30A 1gtnG-5eulY:
undetectable
1gtnH-5eulY:
undetectable
1gtnG-5eulY:
10.61
1gtnH-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)
5eul AYC08
(Vicugna
pacos)
3 / 3 TRP V  36
TYR V  96
LEU V   4
None
1.00A 1kxhA-5eulV:
undetectable
1kxhA-5eulV:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 11 PHE Y 374
VAL Y 406
GLY Y 407
VAL Y 266
ILE Y 234
None
0.84A 1phgA-5eulY:
undetectable
1phgA-5eulY:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
THR Y 412
None
1.28A 1utdA-5eulY:
undetectable
1utdB-5eulY:
undetectable
1utdA-5eulY:
10.61
1utdB-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
THR Y 412
None
1.28A 1utdC-5eulY:
undetectable
1utdD-5eulY:
undetectable
1utdC-5eulY:
10.61
1utdD-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
THR Y 412
None
1.27A 1utdD-5eulY:
undetectable
1utdE-5eulY:
undetectable
1utdD-5eulY:
10.61
1utdE-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
THR Y 412
None
1.26A 1utdG-5eulY:
undetectable
1utdH-5eulY:
undetectable
1utdG-5eulY:
10.61
1utdH-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.27A 1utdA-5eulY:
undetectable
1utdK-5eulY:
undetectable
1utdA-5eulY:
10.61
1utdK-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 11 GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
THR Y 412
None
1.30A 1utdM-5eulY:
undetectable
1utdN-5eulY:
undetectable
1utdM-5eulY:
10.61
1utdN-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_B_CAMB2422_0
(CYTOCHROME P450-CAM)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 PHE Y 374
VAL Y 406
GLY Y 407
VAL Y 266
ILE Y 234
None
0.93A 2a1oB-5eulY:
undetectable
2a1oB-5eulY:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)
5eul PREPROTEIN
TRANSLOCASE SECE
SUBUNIT
PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
3 / 3 ASP E  48
PHE Y  33
ARG Y  29
None
0.84A 2a3aA-5eulE:
undetectable
2a3aA-5eulE:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGQ_A_PCFA1275_0
(WNT INHIBITORY
FACTOR 1)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 12 ILE Y 228
LEU Y 402
PRO Y 382
ILE Y 378
PHE Y 374
None
1.07A 2ygqA-5eulY:
undetectable
2ygqA-5eulY:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
4 / 7 PHE Y 132
MET Y 128
ILE Y  58
ASN Y  57
None
1.24A 2zseA-5eulY:
undetectable
2zseA-5eulY:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)
5eul AYC08
PROTEIN TRANSLOCASE
SUBUNIT SECY

(Vicugna
pacos;
Geobacillus
thermodenitrific
ans)
3 / 3 LEU Y  46
TRP V 107
GLY V 108
None
0.80A 3l35B-5eulY:
undetectable
3l35K-5eulY:
undetectable
3l35B-5eulY:
8.08
3l35K-5eulY:
3.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_0
(METHYLTRANSFERASE)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 12 TYR Y 365
PHE Y 374
ALA Y 327
THR Y 323
ILE Y 319
None
1.33A 3ndiA-5eulY:
undetectable
3ndiA-5eulY:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VKX_A_T3A301_1
(PROLIFERATING CELL
NUCLEAR ANTIGEN)
5eul AYC08
(Vicugna
pacos)
4 / 6 LEU V   4
PRO V 105
GLN V  98
TYR V  97
None
1.35A 3vkxA-5eulV:
undetectable
3vkxA-5eulV:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
5eul PREPROTEIN
TRANSLOCASE SECE
SUBUNIT
PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans;
Geobacillus
thermodenitrific
ans)
4 / 8 PHE E  40
THR Y  21
THR E  36
VAL Y 408
None
1.00A 4l4aA-5eulE:
undetectable
4l4aA-5eulE:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)
5eul AYC08
PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans;
Vicugna
pacos)
5 / 12 GLU V  46
LEU Y 140
GLY V  35
PHE V  67
ASP V  89
None
1.05A 4xe5A-5eulV:
undetectable
4xe5A-5eulV:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPM_A_BO2A801_1
(LON PROTEASE)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 12 ALA Y 153
THR Y 157
LEU Y 150
GLY Y 127
SER Y 129
None
1.12A 4ypmA-5eulY:
undetectable
4ypmA-5eulY:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 5eeuA-5eulY:
undetectable
5eeuB-5eulY:
undetectable
5eeuA-5eulY:
10.61
5eeuB-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.29A 5eeuB-5eulY:
undetectable
5eeuC-5eulY:
undetectable
5eeuB-5eulY:
10.61
5eeuC-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.29A 5eeuC-5eulY:
undetectable
5eeuD-5eulY:
undetectable
5eeuC-5eulY:
10.61
5eeuD-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 5eeuD-5eulY:
undetectable
5eeuE-5eulY:
undetectable
5eeuD-5eulY:
10.61
5eeuE-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.27A 5eeuE-5eulY:
undetectable
5eeuF-5eulY:
undetectable
5eeuE-5eulY:
10.61
5eeuF-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.30A 5eeuG-5eulY:
undetectable
5eeuH-5eulY:
undetectable
5eeuG-5eulY:
10.61
5eeuH-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.27A 5eeuH-5eulY:
undetectable
5eeuI-5eulY:
undetectable
5eeuH-5eulY:
10.61
5eeuI-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.26A 5eeuJ-5eulY:
undetectable
5eeuK-5eulY:
undetectable
5eeuJ-5eulY:
10.61
5eeuK-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
THR Y 412
None
1.28A 5eeuA-5eulY:
undetectable
5eeuK-5eulY:
undetectable
5eeuA-5eulY:
10.61
5eeuK-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.29A 5eevB-5eulY:
undetectable
5eevC-5eulY:
undetectable
5eevB-5eulY:
10.61
5eevC-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.29A 5eevC-5eulY:
undetectable
5eevD-5eulY:
undetectable
5eevC-5eulY:
10.61
5eevD-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 5eevD-5eulY:
undetectable
5eevE-5eulY:
undetectable
5eevD-5eulY:
10.61
5eevE-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.27A 5eevE-5eulY:
undetectable
5eevF-5eulY:
undetectable
5eevE-5eulY:
10.61
5eevF-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.30A 5eevG-5eulY:
undetectable
5eevH-5eulY:
undetectable
5eevG-5eulY:
10.61
5eevH-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.27A 5eevH-5eulY:
undetectable
5eevI-5eulY:
undetectable
5eevH-5eulY:
10.61
5eevI-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.25A 5eevJ-5eulY:
undetectable
5eevK-5eulY:
undetectable
5eevJ-5eulY:
10.61
5eevK-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
THR Y 412
None
1.28A 5eevA-5eulY:
undetectable
5eevK-5eulY:
undetectable
5eevA-5eulY:
10.61
5eevK-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
THR Y 412
None
1.30A 5eevU-5eulY:
undetectable
5eevV-5eulY:
undetectable
5eevU-5eulY:
10.61
5eevV-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.29A 5eewB-5eulY:
undetectable
5eewC-5eulY:
undetectable
5eewB-5eulY:
10.61
5eewC-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.29A 5eewC-5eulY:
undetectable
5eewD-5eulY:
undetectable
5eewC-5eulY:
10.61
5eewD-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 5eewD-5eulY:
undetectable
5eewE-5eulY:
undetectable
5eewD-5eulY:
10.61
5eewE-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.27A 5eewE-5eulY:
undetectable
5eewF-5eulY:
undetectable
5eewE-5eulY:
10.61
5eewF-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.30A 5eewG-5eulY:
undetectable
5eewH-5eulY:
undetectable
5eewG-5eulY:
10.61
5eewH-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.27A 5eewH-5eulY:
undetectable
5eewI-5eulY:
undetectable
5eewH-5eulY:
10.61
5eewI-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.26A 5eewJ-5eulY:
undetectable
5eewK-5eulY:
undetectable
5eewJ-5eulY:
10.61
5eewK-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
THR Y 412
None
1.28A 5eewA-5eulY:
undetectable
5eewK-5eulY:
undetectable
5eewA-5eulY:
10.61
5eewK-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
THR Y 412
None
1.30A 5eewU-5eulY:
undetectable
5eewV-5eulY:
undetectable
5eewU-5eulY:
10.61
5eewV-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.29A 5eexB-5eulY:
undetectable
5eexC-5eulY:
undetectable
5eexB-5eulY:
10.61
5eexC-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.29A 5eexC-5eulY:
undetectable
5eexD-5eulY:
undetectable
5eexC-5eulY:
10.61
5eexD-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 5eexD-5eulY:
undetectable
5eexE-5eulY:
undetectable
5eexD-5eulY:
10.61
5eexE-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.27A 5eexE-5eulY:
undetectable
5eexF-5eulY:
undetectable
5eexE-5eulY:
10.61
5eexF-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.30A 5eexG-5eulY:
undetectable
5eexH-5eulY:
undetectable
5eexG-5eulY:
10.61
5eexH-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.27A 5eexH-5eulY:
undetectable
5eexI-5eulY:
undetectable
5eexH-5eulY:
10.61
5eexI-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 11 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 5eexI-5eulY:
undetectable
5eexJ-5eulY:
undetectable
5eexI-5eulY:
10.61
5eexJ-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.26A 5eexJ-5eulY:
undetectable
5eexK-5eulY:
undetectable
5eexJ-5eulY:
10.61
5eexK-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
THR Y 412
None
1.28A 5eexA-5eulY:
undetectable
5eexK-5eulY:
undetectable
5eexA-5eulY:
10.61
5eexK-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
THR Y 412
None
1.30A 5eexU-5eulY:
undetectable
5eexV-5eulY:
undetectable
5eexU-5eulY:
10.61
5eexV-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.29A 5eeyB-5eulY:
undetectable
5eeyC-5eulY:
undetectable
5eeyB-5eulY:
10.61
5eeyC-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.29A 5eeyC-5eulY:
undetectable
5eeyD-5eulY:
undetectable
5eeyC-5eulY:
10.61
5eeyD-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 5eeyD-5eulY:
undetectable
5eeyE-5eulY:
undetectable
5eeyD-5eulY:
10.61
5eeyE-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.27A 5eeyE-5eulY:
undetectable
5eeyF-5eulY:
undetectable
5eeyE-5eulY:
10.61
5eeyF-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.30A 5eeyG-5eulY:
undetectable
5eeyH-5eulY:
undetectable
5eeyG-5eulY:
10.61
5eeyH-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 5eeyH-5eulY:
undetectable
5eeyI-5eulY:
undetectable
5eeyH-5eulY:
10.61
5eeyI-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 11 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 5eeyI-5eulY:
undetectable
5eeyJ-5eulY:
undetectable
5eeyI-5eulY:
10.61
5eeyJ-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.26A 5eeyJ-5eulY:
undetectable
5eeyK-5eulY:
undetectable
5eeyJ-5eulY:
10.61
5eeyK-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
THR Y 412
None
1.28A 5eeyA-5eulY:
undetectable
5eeyK-5eulY:
undetectable
5eeyA-5eulY:
10.61
5eeyK-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
THR Y 412
None
1.30A 5eeyU-5eulY:
undetectable
5eeyV-5eulY:
undetectable
5eeyU-5eulY:
10.61
5eeyV-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.29A 5eezB-5eulY:
undetectable
5eezC-5eulY:
undetectable
5eezB-5eulY:
10.61
5eezC-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.29A 5eezC-5eulY:
undetectable
5eezD-5eulY:
undetectable
5eezC-5eulY:
10.61
5eezD-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 5eezD-5eulY:
undetectable
5eezE-5eulY:
undetectable
5eezD-5eulY:
10.61
5eezE-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.27A 5eezE-5eulY:
undetectable
5eezF-5eulY:
undetectable
5eezE-5eulY:
10.61
5eezF-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.30A 5eezG-5eulY:
undetectable
5eezH-5eulY:
undetectable
5eezG-5eulY:
10.61
5eezH-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 5eezH-5eulY:
undetectable
5eezI-5eulY:
undetectable
5eezH-5eulY:
10.61
5eezI-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 11 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 5eezI-5eulY:
undetectable
5eezJ-5eulY:
undetectable
5eezI-5eulY:
10.61
5eezJ-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.26A 5eezJ-5eulY:
undetectable
5eezK-5eulY:
undetectable
5eezJ-5eulY:
10.61
5eezK-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
THR Y 412
None
1.28A 5eezA-5eulY:
undetectable
5eezK-5eulY:
undetectable
5eezA-5eulY:
10.61
5eezK-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
THR Y 412
None
1.31A 5eezU-5eulY:
undetectable
5eezV-5eulY:
undetectable
5eezU-5eulY:
10.61
5eezV-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.29A 5ef0B-5eulY:
undetectable
5ef0C-5eulY:
undetectable
5ef0B-5eulY:
10.61
5ef0C-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.29A 5ef0C-5eulY:
undetectable
5ef0D-5eulY:
undetectable
5ef0C-5eulY:
10.61
5ef0D-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 5ef0D-5eulY:
undetectable
5ef0E-5eulY:
undetectable
5ef0D-5eulY:
10.61
5ef0E-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.27A 5ef0E-5eulY:
undetectable
5ef0F-5eulY:
undetectable
5ef0E-5eulY:
10.61
5ef0F-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.30A 5ef0G-5eulY:
undetectable
5ef0H-5eulY:
undetectable
5ef0G-5eulY:
10.61
5ef0H-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 5ef0H-5eulY:
undetectable
5ef0I-5eulY:
undetectable
5ef0H-5eulY:
10.61
5ef0I-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 11 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 5ef0I-5eulY:
undetectable
5ef0J-5eulY:
undetectable
5ef0I-5eulY:
10.61
5ef0J-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.26A 5ef0J-5eulY:
undetectable
5ef0K-5eulY:
undetectable
5ef0J-5eulY:
10.61
5ef0K-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
THR Y 412
None
1.28A 5ef0A-5eulY:
undetectable
5ef0K-5eulY:
undetectable
5ef0A-5eulY:
10.61
5ef0K-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
THR Y 412
None
1.33A 5ef0T-5eulY:
undetectable
5ef0U-5eulY:
undetectable
5ef0T-5eulY:
10.61
5ef0U-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
THR Y 412
None
1.31A 5ef0U-5eulY:
undetectable
5ef0V-5eulY:
undetectable
5ef0U-5eulY:
10.61
5ef0V-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.29A 5ef1B-5eulY:
undetectable
5ef1C-5eulY:
undetectable
5ef1B-5eulY:
10.61
5ef1C-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.29A 5ef1C-5eulY:
undetectable
5ef1D-5eulY:
undetectable
5ef1C-5eulY:
10.61
5ef1D-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 5ef1D-5eulY:
undetectable
5ef1E-5eulY:
undetectable
5ef1D-5eulY:
10.61
5ef1E-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.27A 5ef1E-5eulY:
undetectable
5ef1F-5eulY:
undetectable
5ef1E-5eulY:
10.61
5ef1F-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.31A 5ef1G-5eulY:
undetectable
5ef1H-5eulY:
undetectable
5ef1G-5eulY:
10.61
5ef1H-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 5ef1H-5eulY:
undetectable
5ef1I-5eulY:
undetectable
5ef1H-5eulY:
10.61
5ef1I-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 11 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 5ef1I-5eulY:
undetectable
5ef1J-5eulY:
undetectable
5ef1I-5eulY:
10.61
5ef1J-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.26A 5ef1J-5eulY:
undetectable
5ef1K-5eulY:
undetectable
5ef1J-5eulY:
10.61
5ef1K-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
THR Y 412
None
1.28A 5ef1A-5eulY:
undetectable
5ef1K-5eulY:
undetectable
5ef1A-5eulY:
10.61
5ef1K-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.29A 5ef2B-5eulY:
undetectable
5ef2C-5eulY:
undetectable
5ef2B-5eulY:
10.61
5ef2C-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.29A 5ef2C-5eulY:
undetectable
5ef2D-5eulY:
undetectable
5ef2C-5eulY:
10.61
5ef2D-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 5ef2D-5eulY:
undetectable
5ef2E-5eulY:
undetectable
5ef2D-5eulY:
10.61
5ef2E-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.27A 5ef2E-5eulY:
undetectable
5ef2F-5eulY:
undetectable
5ef2E-5eulY:
10.61
5ef2F-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.31A 5ef2G-5eulY:
undetectable
5ef2H-5eulY:
undetectable
5ef2G-5eulY:
10.61
5ef2H-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 5ef2H-5eulY:
undetectable
5ef2I-5eulY:
undetectable
5ef2H-5eulY:
10.61
5ef2I-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 11 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 5ef2I-5eulY:
undetectable
5ef2J-5eulY:
undetectable
5ef2I-5eulY:
10.61
5ef2J-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.26A 5ef2J-5eulY:
undetectable
5ef2K-5eulY:
undetectable
5ef2J-5eulY:
10.61
5ef2K-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
THR Y 412
None
1.28A 5ef2A-5eulY:
undetectable
5ef2K-5eulY:
undetectable
5ef2A-5eulY:
10.61
5ef2K-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.29A 5ef3B-5eulY:
undetectable
5ef3C-5eulY:
undetectable
5ef3B-5eulY:
10.61
5ef3C-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.29A 5ef3C-5eulY:
undetectable
5ef3D-5eulY:
undetectable
5ef3C-5eulY:
10.61
5ef3D-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 5ef3D-5eulY:
undetectable
5ef3E-5eulY:
undetectable
5ef3D-5eulY:
10.61
5ef3E-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.27A 5ef3E-5eulY:
undetectable
5ef3F-5eulY:
undetectable
5ef3E-5eulY:
10.61
5ef3F-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.31A 5ef3G-5eulY:
undetectable
5ef3H-5eulY:
undetectable
5ef3G-5eulY:
10.61
5ef3H-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 5ef3H-5eulY:
undetectable
5ef3I-5eulY:
undetectable
5ef3H-5eulY:
10.61
5ef3I-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 11 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.28A 5ef3I-5eulY:
undetectable
5ef3J-5eulY:
undetectable
5ef3I-5eulY:
10.61
5ef3J-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 9 THR Y 412
GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
None
1.26A 5ef3J-5eulY:
undetectable
5ef3K-5eulY:
undetectable
5ef3J-5eulY:
10.61
5ef3K-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
5 / 10 GLY Y 178
ALA Y 185
THR Y  21
ILE Y 182
THR Y 412
None
1.28A 5ef3A-5eulY:
undetectable
5ef3K-5eulY:
undetectable
5ef3A-5eulY:
10.61
5ef3K-5eulY:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
4 / 8 ALA Y 153
THR Y 157
THR Y 160
ALA Y  80
None
0.88A 5x2tI-5eulY:
undetectable
5x2tJ-5eulY:
undetectable
5x2tK-5eulY:
undetectable
5x2tL-5eulY:
undetectable
5x2tI-5eulY:
17.20
5x2tJ-5eulY:
15.31
5x2tK-5eulY:
17.20
5x2tL-5eulY:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_1
(TYROSINE-PROTEIN
KINASE ABL1)
5eul PROTEIN TRANSLOCASE
SUBUNIT SECY

(Geobacillus
thermodenitrific
ans)
4 / 5 TYR Y 149
ILE Y  34
MET Y 128
GLY Y 131
None
1.02A 6hd6A-5eulY:
undetectable
6hd6A-5eulY:
9.90