SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5euo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQT_A_AINA596_1
(LACTOPEROXIDASE)		 5euo PF6 TCR BETA CHAIN
(Homo
sapiens) 		4 / 6 HIS F 150
ARG F 106
GLN F   4
PRO F 103
 None
 1.35A 2qqtA-5euoF:
undetectable		 2qqtA-5euoF:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		 5euo PF6 TCR BETA CHAIN
(Homo
sapiens) 		4 / 6 HIS F 150
ARG F 106
GLN F   4
PRO F 103
 None
 1.33A 3gclA-5euoF:
undetectable		 3gclA-5euoF:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5euo PF6 TCR BETA CHAIN
(Homo
sapiens) 		3 / 3 TYR F  46
GLY F  56
ASP F  57
 None
 0.57A 3ou6C-5euoF:
undetectable		 3ou6C-5euoF:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_B_ACHB301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5euo PF6 TCR BETA CHAIN
(Homo
sapiens) 		4 / 8 TYR F  62
THR F  18
TYR F  87
TRP F  32
 None
 1.23A 3wipB-5euoF:
3.0
3wipC-5euoF:
undetectable		 3wipB-5euoF:
21.76
3wipC-5euoF:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_C_ACHC301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5euo PF6 TCR BETA CHAIN
(Homo
sapiens) 		4 / 8 TYR F  62
THR F  18
TYR F  87
TRP F  32
 None
 1.24A 3wipC-5euoF:
undetectable
3wipD-5euoF:
undetectable		 3wipC-5euoF:
21.76
3wipD-5euoF:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_E_ACHE301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5euo PF6 TCR BETA CHAIN
(Homo
sapiens) 		4 / 8 TRP F  32
TYR F  62
THR F  18
TYR F  87
 None
 1.33A 3wipA-5euoF:
undetectable
3wipE-5euoF:
undetectable		 3wipA-5euoF:
21.76
3wipE-5euoF:
21.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 5euo PF6 TCR BETA CHAIN
(Homo
sapiens) 		5 / 8 TYR F  45
LYS F  55
SER F  63
THR F  75
THR F  77
 None
 0.61A 5jhdE-5euoF:
31.0
5jhdG-5euoF:
11.1		 5jhdE-5euoF:
95.83
5jhdG-5euoF:
17.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JHD_J_EDTJ301_0
(TCRBETA CHAIN)		 5euo PF6 TCR BETA CHAIN
(Homo
sapiens) 		4 / 5 TYR F  45
LYS F  55
GLY F  61
SER F  63
 None
 0.51A 5jhdJ-5euoF:
30.7		 5jhdJ-5euoF:
95.83