SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5eup'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2N27_A_4DYA205_1
(CALMODULIN)		 5eup CENTROSOME-ASSOCIATE
D ZINC FINGER
PROTEIN CP190
(Drosophila
melanogaster) 		5 / 11 LEU A 116
THR A 106
LEU A  34
MET A  72
VAL A  81
 None
 1.40A 2n27A-5eupA:
undetectable		 2n27A-5eupA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_D_TPFD490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 5eup CENTROSOME-ASSOCIATE
D ZINC FINGER
PROTEIN CP190
(Drosophila
melanogaster) 		4 / 8 MET A  72
PHE A  36
ALA A  78
LEU A  49
 None
 1.02A 3l4dD-5eupA:
undetectable		 3l4dD-5eupA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS6_A_J3ZA302_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE 14)		 5eup CENTROSOME-ASSOCIATE
D ZINC FINGER
PROTEIN CP190
(Drosophila
melanogaster) 		4 / 8 LEU A 118
LEU A 115
MET A 110
THR A  53
 None
 0.81A 5hs6A-5eupA:
undetectable		 5hs6A-5eupA:
20.58