SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5eus'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ASD_A_BAXA1500_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 5eus PRESTIN,RAT PRESTIN
STAS DOMAIN
(Rattus
norvegicus) 		4 / 6 ILE A 639
VAL A 674
LEU A 676
ILE A 643
 None
 0.80A 4asdA-5eusA:
undetectable		 4asdA-5eusA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_1
(CYTOCHROME P450 2C9)		 5eus PRESTIN,RAT PRESTIN
STAS DOMAIN
(Rattus
norvegicus) 		5 / 12 ALA A 547
GLY A 662
ALA A 661
LEU A 701
LEU A 676
 None
None
None
PG4  A 806 ( 4.3A)
None
 1.08A 5xxiA-5eusA:
undetectable		 5xxiA-5eusA:
16.22