SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5eut'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Homo
sapiens;
Escherichia
virus
T4) 		3 / 3 ASP A 396
ASP A 390
LYS A 202
 None
 1.15A 1lqtB-5eutA:
undetectable		 1lqtB-5eutA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Homo
sapiens;
Escherichia
virus
T4) 		3 / 3 ASP A 396
ASP A 390
LYS A 202
 None
 1.17A 1lquB-5eutA:
undetectable		 1lquB-5eutA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ALA A1131
PHE A1155
LEU A1135
ALA A1132
ILE A1080
 None
 0.88A 2aclA-5eutA:
undetectable
2aclE-5eutA:
undetectable		 2aclA-5eutA:
18.96
2aclE-5eutA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Homo
sapiens;
Escherichia
virus
T4) 		3 / 3 LYS A 256
TYR A 138
PRO A 153
 None
 1.24A 2j9cC-5eutA:
undetectable		 2j9cC-5eutA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Homo
sapiens;
Escherichia
virus
T4) 		3 / 3 PRO A1145
ASN A1146
ARG A1150
 None
 0.94A 2qeuB-5eutA:
undetectable		 2qeuB-5eutA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 6 LEU A 297
LEU A 300
ASP A 301
TRP A 366
 None
 1.01A 2rlfB-5eutA:
undetectable
2rlfC-5eutA:
undetectable		 2rlfB-5eutA:
13.23
2rlfC-5eutA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_D_TC9D1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 8 THR A1036
TYR A1027
ILE A1019
SER A1038
 None
 1.12A 2xytE-5eutA:
undetectable		 2xytE-5eutA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 8 THR A1036
TYR A1027
ILE A1019
SER A1038
 None
 1.07A 2xytH-5eutA:
undetectable		 2xytH-5eutA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 7 THR A1036
TYR A1027
ILE A1019
SER A1038
 None
 1.11A 2xytI-5eutA:
undetectable		 2xytI-5eutA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 ASN A 437
ASP A 436
ILE A 427
GLY A 425
LEU A 385
 None
 1.07A 3eeyF-5eutA:
undetectable		 3eeyF-5eutA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 10 ALA A1131
PHE A1155
LEU A1135
ALA A1132
ILE A1080
 None
 0.98A 3falC-5eutA:
undetectable		 3falC-5eutA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 11 ALA A1131
PHE A1155
LEU A1135
ALA A1132
ILE A1080
 None
 0.93A 3fc6A-5eutA:
undetectable		 3fc6A-5eutA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 HIS A 355
PHE A 351
ILE A 303
LEU A 353
LYS A 418
 None
 1.19A 3fzgA-5eutA:
undetectable		 3fzgA-5eutA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 7 ILE A 420
LYS A 407
PHE A 351
GLY A 195
 None
 1.13A 3sj0X-5eutA:
undetectable		 3sj0X-5eutA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA501_1
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ILE A 304
ASP A 301
VAL A 342
ASP A 200
ILE A 207
 None
 1.36A 4i41A-5eutA:
6.5		 4i41A-5eutA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 10 LEU A 203
LEU A 385
ILE A 427
LEU A 430
LEU A 397
 None
 1.01A 4odoA-5eutA:
undetectable		 4odoA-5eutA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 10 LEU A 203
LEU A 385
ILE A 427
LEU A 430
LEU A 397
 None
 1.01A 4odoB-5eutA:
undetectable		 4odoB-5eutA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 10 LEU A 203
LEU A 385
ILE A 427
LEU A 430
LEU A 397
 None
 1.04A 4odoC-5eutA:
undetectable		 4odoC-5eutA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_C_PACC601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 PHE A 416
PHE A 405
GLN A 419
ILE A 420
VAL A 199
 None
 1.48A 4yfbC-5eutA:
undetectable		 4yfbC-5eutA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_F_PACF601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 PHE A 416
PHE A 405
GLN A 419
ILE A 420
VAL A 199
 None
 1.45A 4yfbF-5eutA:
undetectable		 4yfbF-5eutA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_I_PACI601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 PHE A 416
PHE A 405
GLN A 419
ILE A 420
VAL A 199
 None
 1.45A 4yfbI-5eutA:
undetectable		 4yfbI-5eutA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_L_PACL601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 PHE A 416
PHE A 405
GLN A 419
ILE A 420
VAL A 199
 None
 1.44A 4yfbL-5eutA:
undetectable		 4yfbL-5eutA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 7 THR A1028
TYR A1020
GLU A1013
HIS A1033
 None
 0.93A 5ecnA-5eutA:
undetectable		 5ecnA-5eutA:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 MET A1104
ALA A1076
VAL A1151
LEU A1123
VAL A1089
 None
 1.28A 5tudD-5eutA:
2.7		 5tudD-5eutA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5eut PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA,ENDOLYSIN,PH
OSPHATIDYLINOSITOL
4-KINASE TYPE
2-ALPHA
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 ALA A1131
PHE A1155
LEU A1135
ALA A1132
ILE A1080
 None
 0.92A 6a5zL-5eutA:
undetectable		 6a5zL-5eutA:
8.44