SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ev7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_1
(HYPOTHETICAL PROTEIN
RV2118C)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
3 / 3 GLU A 282
HIS A 285
ASP A 247
None
0.70A 1i9gA-5ev7A:
undetectable
1i9gA-5ev7A:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA257_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 4 THR A 256
ALA A 251
GLN A 286
MET A  67
None
1.49A 1jgsA-5ev7A:
0.0
1jgsA-5ev7A:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.46A 1k2rA-5ev7A:
undetectable
1k2rB-5ev7A:
undetectable
1k2rA-5ev7A:
20.63
1k2rB-5ev7A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.47A 1k2tA-5ev7A:
undetectable
1k2tB-5ev7A:
undetectable
1k2tA-5ev7A:
20.63
1k2tB-5ev7A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.45A 1m00A-5ev7A:
undetectable
1m00B-5ev7A:
undetectable
1m00A-5ev7A:
20.63
1m00B-5ev7A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.49A 1m00A-5ev7A:
undetectable
1m00B-5ev7A:
undetectable
1m00A-5ev7A:
20.63
1m00B-5ev7A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.44A 1mmvA-5ev7A:
undetectable
1mmvB-5ev7A:
undetectable
1mmvA-5ev7A:
20.63
1mmvB-5ev7A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
5 / 12 ILE A 401
PHE A 404
ALA A 411
LEU A 353
PHE A 388
None
1.20A 1og5B-5ev7A:
undetectable
1og5B-5ev7A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.46A 1om4A-5ev7A:
undetectable
1om4B-5ev7A:
undetectable
1om4A-5ev7A:
20.59
1om4B-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 8 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.42A 1om5A-5ev7A:
undetectable
1om5B-5ev7A:
undetectable
1om5A-5ev7A:
20.63
1om5B-5ev7A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
5 / 12 TRP A 292
THR A 415
ILE A 419
ILE A 389
THR A 291
None
1.12A 1re7A-5ev7A:
undetectable
1re7A-5ev7A:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 5 GLU A 264
THR A 273
LEU A 269
LEU A 272
None
1.15A 1u18B-5ev7A:
undetectable
1u18B-5ev7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.47A 1zzqA-5ev7A:
undetectable
1zzqB-5ev7A:
undetectable
1zzqA-5ev7A:
20.59
1zzqB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.46A 1zzqA-5ev7A:
undetectable
1zzqB-5ev7A:
undetectable
1zzqA-5ev7A:
20.59
1zzqB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 8 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.44A 2g6hA-5ev7A:
undetectable
2g6hB-5ev7A:
undetectable
2g6hA-5ev7A:
20.59
2g6hB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.43A 2g6kA-5ev7A:
undetectable
2g6kB-5ev7A:
undetectable
2g6kA-5ev7A:
20.59
2g6kB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.44A 2g6mA-5ev7A:
undetectable
2g6mB-5ev7A:
undetectable
2g6mA-5ev7A:
20.59
2g6mB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.45A 2g6mA-5ev7A:
undetectable
2g6mB-5ev7A:
undetectable
2g6mA-5ev7A:
20.59
2g6mB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 8 GLU A 216
PHE A  69
HIS A 287
GLY A 284
None
1.04A 2ha4A-5ev7A:
undetectable
2ha4A-5ev7A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_C_STIC600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 6 LEU A  62
VAL A 464
MET A 463
ILE A 491
None
1.05A 2hyyC-5ev7A:
undetectable
2hyyC-5ev7A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_A_IPHA2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 5 PRO A 109
TYR A 254
TYR A 130
PRO A  71
None
0.89A 2ombA-5ev7A:
undetectable
2ombB-5ev7A:
undetectable
2ombA-5ev7A:
17.56
2ombB-5ev7A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 TYR A  98
PRO A 109
TYR A 254
HIS A 238
None
0.78A 2ombC-5ev7A:
undetectable
2ombD-5ev7A:
undetectable
2ombC-5ev7A:
17.56
2ombD-5ev7A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 TYR A 130
PRO A  71
PRO A 109
TYR A 254
None
1.10A 2ombC-5ev7A:
undetectable
2ombD-5ev7A:
undetectable
2ombC-5ev7A:
17.56
2ombD-5ev7A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
5 / 7 TYR A 254
HIS A 238
TYR A  98
PRO A 109
TYR A 130
None
0.95A 2ombC-5ev7A:
undetectable
2ombD-5ev7A:
undetectable
2ombC-5ev7A:
17.56
2ombD-5ev7A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_A_LDPA501_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
5 / 7 TRP A 294
GLY A 298
PHE A 350
ILE A 304
PHE A 388
None
1.41A 2qmzA-5ev7A:
undetectable
2qmzB-5ev7A:
undetectable
2qmzA-5ev7A:
16.13
2qmzB-5ev7A:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.44A 3b3mA-5ev7A:
undetectable
3b3mB-5ev7A:
undetectable
3b3mA-5ev7A:
20.59
3b3mB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.47A 3b3nA-5ev7A:
undetectable
3b3nB-5ev7A:
undetectable
3b3nA-5ev7A:
20.59
3b3nB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.45A 3b3oA-5ev7A:
undetectable
3b3oB-5ev7A:
undetectable
3b3oA-5ev7A:
20.59
3b3oB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.44A 3b3pA-5ev7A:
undetectable
3b3pB-5ev7A:
undetectable
3b3pA-5ev7A:
20.59
3b3pB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 5 ILE A 431
THR A 392
PHE A 388
PHE A 350
None
1.16A 3em0A-5ev7A:
undetectable
3em0A-5ev7A:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 8 VAL A 348
TRP A 351
GLN A 352
GLY A 323
None
0.68A 3hjoA-5ev7A:
undetectable
3hjoA-5ev7A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.45A 3hsnA-5ev7A:
undetectable
3hsnB-5ev7A:
undetectable
3hsnA-5ev7A:
20.59
3hsnB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.49A 3hsnA-5ev7A:
undetectable
3hsnB-5ev7A:
undetectable
3hsnA-5ev7A:
20.59
3hsnB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.48A 3hsoA-5ev7A:
undetectable
3hsoB-5ev7A:
undetectable
3hsoA-5ev7A:
20.59
3hsoB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.45A 3jt4A-5ev7A:
undetectable
3jt4B-5ev7A:
undetectable
3jt4A-5ev7A:
20.59
3jt4B-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.44A 3jt5A-5ev7A:
undetectable
3jt5B-5ev7A:
undetectable
3jt5A-5ev7A:
20.59
3jt5B-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.50A 3jt7A-5ev7A:
undetectable
3jt7B-5ev7A:
undetectable
3jt7A-5ev7A:
20.59
3jt7B-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.45A 3jt8A-5ev7A:
undetectable
3jt8B-5ev7A:
undetectable
3jt8A-5ev7A:
20.59
3jt8B-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.44A 3jt9A-5ev7A:
undetectable
3jt9B-5ev7A:
undetectable
3jt9A-5ev7A:
20.59
3jt9B-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.50A 3jtaA-5ev7A:
undetectable
3jtaB-5ev7A:
undetectable
3jtaA-5ev7A:
20.59
3jtaB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.44A 3jwsA-5ev7A:
undetectable
3jwsB-5ev7A:
undetectable
3jwsA-5ev7A:
20.59
3jwsB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.46A 3jwsA-5ev7A:
undetectable
3jwsB-5ev7A:
undetectable
3jwsA-5ev7A:
20.59
3jwsB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.46A 3jwtA-5ev7A:
undetectable
3jwtB-5ev7A:
undetectable
3jwtA-5ev7A:
20.59
3jwtB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.45A 3jwtA-5ev7A:
undetectable
3jwtB-5ev7A:
undetectable
3jwtA-5ev7A:
20.59
3jwtB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.44A 3jwuA-5ev7A:
undetectable
3jwuB-5ev7A:
undetectable
3jwuA-5ev7A:
20.59
3jwuB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.45A 3jwuA-5ev7A:
undetectable
3jwuB-5ev7A:
undetectable
3jwuA-5ev7A:
20.59
3jwuB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.45A 3jwvA-5ev7A:
undetectable
3jwvB-5ev7A:
undetectable
3jwvA-5ev7A:
20.59
3jwvB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.42A 3jwvA-5ev7A:
undetectable
3jwvB-5ev7A:
undetectable
3jwvA-5ev7A:
20.59
3jwvB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.43A 3jx0A-5ev7A:
undetectable
3jx0B-5ev7A:
undetectable
3jx0A-5ev7A:
20.59
3jx0B-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.43A 3jx1A-5ev7A:
undetectable
3jx1B-5ev7A:
undetectable
3jx1A-5ev7A:
20.59
3jx1B-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.49A 3n5yA-5ev7A:
undetectable
3n5yB-5ev7A:
undetectable
3n5yA-5ev7A:
20.59
3n5yB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.48A 3n5zA-5ev7A:
undetectable
3n5zB-5ev7A:
undetectable
3n5zA-5ev7A:
20.59
3n5zB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.43A 3nlkA-5ev7A:
undetectable
3nlkB-5ev7A:
undetectable
3nlkA-5ev7A:
20.59
3nlkB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.46A 3nlkA-5ev7A:
undetectable
3nlkB-5ev7A:
undetectable
3nlkA-5ev7A:
20.59
3nlkB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.46A 3nlmA-5ev7A:
undetectable
3nlmB-5ev7A:
undetectable
3nlmA-5ev7A:
20.59
3nlmB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.44A 3nlmA-5ev7A:
undetectable
3nlmB-5ev7A:
undetectable
3nlmA-5ev7A:
20.59
3nlmB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.42A 3nlnA-5ev7A:
undetectable
3nlnB-5ev7A:
undetectable
3nlnA-5ev7A:
20.59
3nlnB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.47A 3nlnA-5ev7A:
undetectable
3nlnB-5ev7A:
undetectable
3nlnA-5ev7A:
20.59
3nlnB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.44A 3nloA-5ev7A:
undetectable
3nloB-5ev7A:
undetectable
3nloA-5ev7A:
20.59
3nloB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.44A 3nloA-5ev7A:
undetectable
3nloB-5ev7A:
undetectable
3nloA-5ev7A:
20.59
3nloB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.41A 3nlvA-5ev7A:
undetectable
3nlvB-5ev7A:
undetectable
3nlvA-5ev7A:
20.59
3nlvB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.45A 3nlvA-5ev7A:
undetectable
3nlvB-5ev7A:
undetectable
3nlvA-5ev7A:
20.59
3nlvB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.48A 3nlxA-5ev7A:
undetectable
3nlxB-5ev7A:
undetectable
3nlxA-5ev7A:
20.59
3nlxB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.45A 3nlxA-5ev7A:
undetectable
3nlxB-5ev7A:
undetectable
3nlxA-5ev7A:
20.59
3nlxB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.46A 3nlzA-5ev7A:
undetectable
3nlzB-5ev7A:
undetectable
3nlzA-5ev7A:
20.59
3nlzB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.47A 3nlzA-5ev7A:
undetectable
3nlzB-5ev7A:
undetectable
3nlzA-5ev7A:
20.59
3nlzB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.43A 3nm0A-5ev7A:
undetectable
3nm0B-5ev7A:
undetectable
3nm0A-5ev7A:
20.59
3nm0B-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.46A 3nnyA-5ev7A:
undetectable
3nnyB-5ev7A:
undetectable
3nnyA-5ev7A:
20.59
3nnyB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.42A 3nnzA-5ev7A:
undetectable
3nnzB-5ev7A:
undetectable
3nnzA-5ev7A:
20.59
3nnzB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.44A 3nnzA-5ev7A:
undetectable
3nnzB-5ev7A:
undetectable
3nnzA-5ev7A:
20.59
3nnzB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.45A 3pneA-5ev7A:
undetectable
3pneB-5ev7A:
undetectable
3pneA-5ev7A:
20.59
3pneB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.45A 3pneA-5ev7A:
undetectable
3pneB-5ev7A:
undetectable
3pneA-5ev7A:
20.59
3pneB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.45A 3pnfA-5ev7A:
undetectable
3pnfB-5ev7A:
undetectable
3pnfA-5ev7A:
20.59
3pnfB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.47A 3pnfA-5ev7A:
undetectable
3pnfB-5ev7A:
undetectable
3pnfA-5ev7A:
20.59
3pnfB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.47A 3pngA-5ev7A:
undetectable
3pngB-5ev7A:
undetectable
3pngA-5ev7A:
20.59
3pngB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.47A 3pngA-5ev7A:
undetectable
3pngB-5ev7A:
undetectable
3pngA-5ev7A:
20.59
3pngB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.48A 3q99A-5ev7A:
undetectable
3q99B-5ev7A:
undetectable
3q99A-5ev7A:
20.59
3q99B-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.47A 3q9aA-5ev7A:
undetectable
3q9aB-5ev7A:
undetectable
3q9aA-5ev7A:
20.59
3q9aB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.46A 3rqkA-5ev7A:
undetectable
3rqkB-5ev7A:
undetectable
3rqkA-5ev7A:
20.59
3rqkB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.46A 3rqmA-5ev7A:
undetectable
3rqmB-5ev7A:
undetectable
3rqmA-5ev7A:
20.59
3rqmB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.46A 3rqmA-5ev7A:
undetectable
3rqmB-5ev7A:
undetectable
3rqmA-5ev7A:
20.59
3rqmB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.47A 3rqnA-5ev7A:
undetectable
3rqnB-5ev7A:
undetectable
3rqnA-5ev7A:
20.59
3rqnB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.48A 3rqnA-5ev7A:
undetectable
3rqnB-5ev7A:
undetectable
3rqnA-5ev7A:
20.59
3rqnB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.49A 3svpA-5ev7A:
undetectable
3svpB-5ev7A:
undetectable
3svpA-5ev7A:
20.59
3svpB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 ASN A 399
PRO A 402
ALA A 411
ARG A 416
None
1.14A 3twpA-5ev7A:
undetectable
3twpA-5ev7A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 ASN A 399
PRO A 402
ALA A 411
ARG A 416
None
1.09A 3twpB-5ev7A:
undetectable
3twpB-5ev7A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 ASN A 399
PRO A 402
ALA A 411
ARG A 416
None
1.10A 3twpC-5ev7A:
undetectable
3twpC-5ev7A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
5 / 10 TYR A 130
ILE A  99
ASN A 151
TYR A 175
GLU A 105
None
0.96A 3u6tA-5ev7A:
undetectable
3u6tA-5ev7A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.46A 3ufuA-5ev7A:
undetectable
3ufuB-5ev7A:
undetectable
3ufuA-5ev7A:
20.59
3ufuB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.48A 3ufuA-5ev7A:
undetectable
3ufuB-5ev7A:
undetectable
3ufuA-5ev7A:
20.59
3ufuB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.46A 3ufvA-5ev7A:
undetectable
3ufvB-5ev7A:
undetectable
3ufvA-5ev7A:
20.59
3ufvB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.48A 4capA-5ev7A:
undetectable
4capB-5ev7A:
undetectable
4capA-5ev7A:
20.59
4capB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.46A 4ctuA-5ev7A:
undetectable
4ctuB-5ev7A:
undetectable
4ctuA-5ev7A:
20.59
4ctuB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.47A 4ctvA-5ev7A:
undetectable
4ctvB-5ev7A:
undetectable
4ctvA-5ev7A:
20.59
4ctvB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.47A 4ctwA-5ev7A:
undetectable
4ctwB-5ev7A:
undetectable
4ctwA-5ev7A:
20.59
4ctwB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.45A 4ctwA-5ev7A:
undetectable
4ctwB-5ev7A:
undetectable
4ctwA-5ev7A:
20.59
4ctwB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.48A 4cx5A-5ev7A:
undetectable
4cx5B-5ev7A:
undetectable
4cx5A-5ev7A:
20.59
4cx5B-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.47A 4cx5A-5ev7A:
undetectable
4cx5B-5ev7A:
undetectable
4cx5A-5ev7A:
20.59
4cx5B-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.46A 4d1nA-5ev7A:
undetectable
4d1nB-5ev7A:
undetectable
4d1nA-5ev7A:
21.51
4d1nB-5ev7A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.46A 4d2yA-5ev7A:
undetectable
4d2yB-5ev7A:
undetectable
4d2yA-5ev7A:
20.59
4d2yB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.47A 4d30A-5ev7A:
undetectable
4d30B-5ev7A:
undetectable
4d30A-5ev7A:
20.59
4d30B-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.45A 4d32A-5ev7A:
undetectable
4d32B-5ev7A:
undetectable
4d32A-5ev7A:
20.59
4d32B-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.47A 4d3bA-5ev7A:
undetectable
4d3bB-5ev7A:
undetectable
4d3bA-5ev7A:
20.59
4d3bB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.46A 4d7oA-5ev7A:
undetectable
4d7oB-5ev7A:
undetectable
4d7oA-5ev7A:
20.59
4d7oB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.47A 4fvwA-5ev7A:
undetectable
4fvwB-5ev7A:
undetectable
4fvwA-5ev7A:
20.59
4fvwB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.45A 4fvxA-5ev7A:
undetectable
4fvxB-5ev7A:
undetectable
4fvxA-5ev7A:
20.59
4fvxB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.48A 4fvzA-5ev7A:
undetectable
4fvzB-5ev7A:
undetectable
4fvzA-5ev7A:
20.59
4fvzB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.46A 4fw0A-5ev7A:
undetectable
4fw0B-5ev7A:
undetectable
4fw0A-5ev7A:
20.59
4fw0B-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.45A 4gqeA-5ev7A:
undetectable
4gqeB-5ev7A:
undetectable
4gqeA-5ev7A:
20.59
4gqeB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 6 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.45A 4imuA-5ev7A:
undetectable
4imuB-5ev7A:
undetectable
4imuA-5ev7A:
20.59
4imuB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.48A 4jsfA-5ev7A:
undetectable
4jsfB-5ev7A:
undetectable
4jsfA-5ev7A:
20.59
4jsfB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.47A 4jsgA-5ev7A:
undetectable
4jsgB-5ev7A:
undetectable
4jsgA-5ev7A:
20.04
4jsgB-5ev7A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.44A 4jsjA-5ev7A:
undetectable
4jsjB-5ev7A:
undetectable
4jsjA-5ev7A:
20.59
4jsjB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.42A 4jsjA-5ev7A:
undetectable
4jsjB-5ev7A:
undetectable
4jsjA-5ev7A:
20.59
4jsjB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.45A 4k5dA-5ev7A:
undetectable
4k5dB-5ev7A:
undetectable
4k5dA-5ev7A:
20.59
4k5dB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.46A 4k5eA-5ev7A:
undetectable
4k5eB-5ev7A:
undetectable
4k5eA-5ev7A:
20.04
4k5eB-5ev7A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.49A 4k5fA-5ev7A:
undetectable
4k5fB-5ev7A:
undetectable
4k5fA-5ev7A:
20.59
4k5fB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.46A 4kchA-5ev7A:
undetectable
4kchB-5ev7A:
undetectable
4kchA-5ev7A:
20.59
4kchB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.47A 4uh1A-5ev7A:
undetectable
4uh1B-5ev7A:
undetectable
4uh1A-5ev7A:
20.59
4uh1B-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.46A 4upmA-5ev7A:
undetectable
4upmB-5ev7A:
undetectable
4upmA-5ev7A:
20.59
4upmB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.44A 4uppA-5ev7A:
undetectable
4uppB-5ev7A:
undetectable
4uppA-5ev7A:
20.59
4uppB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.42A 4uppA-5ev7A:
undetectable
4uppB-5ev7A:
undetectable
4uppA-5ev7A:
20.59
4uppB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.45A 4v3uA-5ev7A:
undetectable
4v3uB-5ev7A:
undetectable
4v3uA-5ev7A:
21.51
4v3uB-5ev7A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.47A 4v3uA-5ev7A:
undetectable
4v3uB-5ev7A:
undetectable
4v3uA-5ev7A:
21.51
4v3uB-5ev7A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.45A 4v3uC-5ev7A:
undetectable
4v3uD-5ev7A:
undetectable
4v3uC-5ev7A:
21.51
4v3uD-5ev7A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.47A 4v3xA-5ev7A:
undetectable
4v3xB-5ev7A:
undetectable
4v3xA-5ev7A:
20.59
4v3xB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.50A 4v3zA-5ev7A:
undetectable
4v3zB-5ev7A:
undetectable
4v3zA-5ev7A:
20.59
4v3zB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.50A 5ad6A-5ev7A:
undetectable
5ad6B-5ev7A:
undetectable
5ad6A-5ev7A:
20.59
5ad6B-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.44A 5aglA-5ev7A:
undetectable
5aglB-5ev7A:
undetectable
5aglA-5ev7A:
20.59
5aglB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.47A 5agmA-5ev7A:
undetectable
5agmB-5ev7A:
undetectable
5agmA-5ev7A:
20.59
5agmB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.49A 5agoA-5ev7A:
undetectable
5agoB-5ev7A:
undetectable
5agoA-5ev7A:
20.59
5agoB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
3 / 3 GLU A 282
HIS A 285
ASP A 247
None
0.76A 5c0oG-5ev7A:
undetectable
5c0oG-5ev7A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 6 TYR A 253
GLY A  58
GLU A  57
ASP A 494
None
1.32A 5emlA-5ev7A:
undetectable
5emlA-5ev7A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.47A 5fw0A-5ev7A:
undetectable
5fw0B-5ev7A:
undetectable
5fw0A-5ev7A:
20.59
5fw0B-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.46A 5g0oA-5ev7A:
undetectable
5g0oB-5ev7A:
undetectable
5g0oA-5ev7A:
20.59
5g0oB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSM_A_GCSA801_1
(EXO-BETA-D-GLUCOSAMI
NIDASE)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
5 / 12 TYR A 130
GLY A 100
GLU A 105
LEU A 185
GLU A 178
None
1.46A 5gsmA-5ev7A:
undetectable
5gsmA-5ev7A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSM_B_GCSB801_1
(EXO-BETA-D-GLUCOSAMI
NIDASE)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
5 / 12 TYR A 130
GLY A 100
GLU A 105
LEU A 185
GLU A 178
None
1.44A 5gsmB-5ev7A:
undetectable
5gsmB-5ev7A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_1
(REGULATORY PROTEIN
TETR)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 8 GLN A 310
GLY A 276
ILE A 212
GLN A 286
None
0.94A 5vlmH-5ev7A:
undetectable
5vlmH-5ev7A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.49A 5vujA-5ev7A:
undetectable
5vujB-5ev7A:
undetectable
5vujA-5ev7A:
20.59
5vujB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.45A 5vulA-5ev7A:
undetectable
5vulB-5ev7A:
undetectable
5vulA-5ev7A:
20.59
5vulB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 PHE A 350
GLU A 345
MET A 341
VAL A 300
None
1.47A 5vulA-5ev7A:
undetectable
5vulB-5ev7A:
undetectable
5vulA-5ev7A:
20.59
5vulB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.46A 5vumA-5ev7A:
undetectable
5vumB-5ev7A:
undetectable
5vumA-5ev7A:
20.59
5vumB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.46A 5vutA-5ev7A:
undetectable
5vutB-5ev7A:
undetectable
5vutA-5ev7A:
20.59
5vutB-5ev7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
4 / 7 MET A 341
VAL A 300
PHE A 350
GLU A 345
None
1.48A 5vv5A-5ev7A:
undetectable
5vv5B-5ev7A:
undetectable
5vv5A-5ev7A:
21.65
5vv5B-5ev7A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
3 / 3 GLN A 367
TYR A 448
ASN A 364
None
1.03A 6dwdC-5ev7A:
undetectable
6dwdC-5ev7A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis)
5 / 12 GLY A 284
GLN A 286
LEU A 293
ILE A 304
TYR A 253
None
1.35A 6md4A-5ev7A:
undetectable
6md4A-5ev7A:
9.62