SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5evj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RV7_B_AB1B1001_1
(PROTEASE)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		6 / 11 ASN A 173
ILE A 167
VAL A 200
LEU A 182
ALA A 185
VAL A 181
 None
 1.44A 1rv7A-5evjA:
undetectable
1rv7B-5evjA:
undetectable		 1rv7A-5evjA:
13.98
1rv7B-5evjA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_2
(HIV-1 PROTEASE)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 12 GLY A 223
ALA A 224
GLY A 218
ALA A 264
VAL A 202
 None
 0.83A 2b7zB-5evjA:
undetectable		 2b7zB-5evjA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_A_SAMA301_0
(YCGJ)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 12 GLY A  91
GLY A  93
ASP A 115
THR A 117
GLU A 151
 None
 0.48A 2gluA-5evjA:
17.5		 2gluA-5evjA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 12 ASP A  89
LEU A  90
GLY A  91
GLY A  93
ASN A 169
 None
 0.74A 2nxeB-5evjA:
12.6		 2nxeB-5evjA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 12 GLY A  91
GLY A  93
GLY A  95
ILE A 150
VAL A 171
 None
 0.69A 2oxtB-5evjA:
6.3		 2oxtB-5evjA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		3 / 3 PRO A  77
ASN A 169
ARG A  96
 None
 1.09A 2qeuB-5evjA:
undetectable		 2qeuB-5evjA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		4 / 8 LEU A 333
GLY A  81
TYR A 332
TYR A 293
 None
 0.85A 3af0A-5evjA:
undetectable		 3af0A-5evjA:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_G_SAMG302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 12 LEU A  90
GLY A  91
GLY A  93
SER A  94
ASN A 169
 None
 0.77A 3cjtG-5evjA:
12.2		 3cjtG-5evjA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 11 GLY A  91
GLY A  93
ASP A 115
THR A 117
GLU A 151
 None
 0.41A 3g88A-5evjA:
11.2		 3g88A-5evjA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 11 GLY A  91
GLY A  93
ASP A 115
THR A 117
GLU A 151
 None
 0.40A 3g88B-5evjA:
11.2		 3g88B-5evjA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 12 GLY A  91
GLY A  93
ASP A 115
THR A 117
GLU A 151
 None
 0.38A 3g89A-5evjA:
11.2		 3g89A-5evjA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 11 GLY A  91
GLY A  93
ASP A 115
THR A 117
GLU A 151
 None
 0.40A 3g89B-5evjA:
10.7		 3g89B-5evjA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 12 GLY A  91
GLY A  93
ASP A 115
THR A 117
GLU A 151
 None
 0.38A 3g8bA-5evjA:
11.2		 3g8bA-5evjA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 12 GLY A  91
GLY A  93
ASP A 115
THR A 117
GLU A 151
 None
 0.45A 3g8bB-5evjA:
10.9		 3g8bB-5evjA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 12 GLY A 218
LEU A 206
VAL A 261
ILE A 252
LEU A 174
 None
 1.17A 3g9eA-5evjA:
undetectable		 3g9eA-5evjA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 12 GLY A 238
ALA A 234
PRO A 277
ALA A 185
PRO A 191
 None
 0.98A 3jb2A-5evjA:
3.8		 3jb2A-5evjA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6G_A_IZPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 12 PHE A  71
VAL A 171
ILE A  78
VAL A 100
ARG A  96
 None
 1.47A 3p6gA-5evjA:
undetectable		 3p6gA-5evjA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		3 / 3 HIS A 196
ARG A 272
GLU A 246
 None
 1.17A 3qf1A-5evjA:
undetectable		 3qf1A-5evjA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 12 GLY A  93
ASP A 115
ILE A 150
VAL A 181
ASN A 173
 None
 1.12A 4a81A-5evjA:
undetectable		 4a81A-5evjA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_C_MIYC392_1
(TETX2 PROTEIN)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 12 GLU A 159
PHE A 163
VAL A 114
ILE A 146
GLU A 184
 None
 1.49A 4a99A-5evjA:
3.3
4a99C-5evjA:
3.3		 4a99A-5evjA:
22.37
4a99C-5evjA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DCM_A_SAMA401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE G)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 11 ASP A  89
GLY A  91
GLY A  93
ASP A 115
ASN A 169
 None
 0.78A 4dcmA-5evjA:
14.2		 4dcmA-5evjA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 11 GLY A 113
ALA A  92
PRO A  77
ILE A  78
ILE A 167
 None
 0.96A 4dt8A-5evjA:
undetectable		 4dt8A-5evjA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 10 GLY A 113
ALA A  92
PRO A  77
ILE A  78
ILE A 167
 None
 0.95A 4dt8B-5evjA:
undetectable		 4dt8B-5evjA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 9 GLU A 281
GLY A 278
PRO A 277
GLU A 194
GLY A 192
 None
 1.13A 4fimA-5evjA:
undetectable		 4fimA-5evjA:
22.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		10 / 12 GLY A  91
GLY A  93
ASP A  97
MET A 116
GLN A 120
ILE A 150
GLU A 151
ASN A 169
VAL A 171
LEU A 174
 None
 0.57A 4fr0A-5evjA:
39.4		 4fr0A-5evjA:
45.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		3 / 3 TYR A 304
PHE A 274
ARG A 272
 None
 1.04A 4g19D-5evjA:
undetectable		 4g19D-5evjA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_ACTA303_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		3 / 3 TYR A 304
HIS A 196
ARG A 272
 None
 1.13A 4htfA-5evjA:
14.0		 4htfA-5evjA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 12 GLY A  93
ASP A  97
ASP A 115
ASN A 169
SER A 175
 None
 1.39A 4pooB-5evjA:
12.0		 4pooB-5evjA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		4 / 5 ALA A 303
TYR A 304
PRO A  53
GLY A  73
 NA  A 401 ( 4.7A)
None
None
None
 0.95A 5eslA-5evjA:
0.7		 5eslA-5evjA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 12 ILE A  82
GLY A  81
ASP A  89
ALA A  59
SER A 198
 None
 1.25A 5igvA-5evjA:
undetectable		 5igvA-5evjA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_1
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		4 / 5 GLY A  93
ARG A  96
ASP A 115
MET A 116
 None
 1.45A 5ubbA-5evjA:
13.3		 5ubbA-5evjA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB308_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		3 / 3 LEU A 165
ILE A  82
TYR A 304
 None
 0.56A 5uunB-5evjA:
undetectable		 5uunB-5evjA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 12 GLY A  91
GLY A  93
ASP A  97
VAL A 171
LEU A 174
 None
 0.90A 6ectA-5evjA:
14.0		 6ectA-5evjA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 5evj ARSENITE
METHYLTRANSFERASE
(Chlamydomonas
reinhardtii) 		4 / 7 GLY A 193
HIS A 336
GLU A  83
GLY A  84
 None
 0.90A 6n7fA-5evjA:
2.2		 6n7fA-5evjA:
13.62