SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5evm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 5evm FUSION GLYCOPROTEIN
F0
(Nipah
henipavirus) 		5 / 12 LEU A 147
PRO A  63
THR A 173
LEU A  83
TYR A  79
 None
 1.26A 1cbrA-5evmA:
undetectable		 1cbrA-5evmA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 5evm FUSION GLYCOPROTEIN
F0
(Nipah
henipavirus) 		5 / 12 LEU A 147
PRO A  63
THR A 173
LEU A  83
TYR A  79
 None
 1.26A 1cbrB-5evmA:
undetectable		 1cbrB-5evmA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_F_CCSF47_0
(GLUTATHIONE
S-TRANSFERASE)		 5evm FUSION GLYCOPROTEIN
F0
(Nipah
henipavirus) 		4 / 5 THR A  81
LEU A  83
GLY A  85
TYR A 274
 None
 1.23A 1gtiF-5evmA:
undetectable		 1gtiF-5evmA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRQ_A_STRA501_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 5evm FUSION GLYCOPROTEIN
F0
(Nipah
henipavirus) 		5 / 11 LEU A  87
VAL A 269
ILE A 276
LEU A 207
LEU A 210
 None
 1.32A 1mrqA-5evmA:
undetectable		 1mrqA-5evmA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5evm FUSION GLYCOPROTEIN
F0
(Nipah
henipavirus) 		4 / 8 ILE A  59
PHE A 214
GLY A 236
GLY A 237
 None
None
MLI  A 611 ( 4.5A)
None
 0.73A 2qx4A-5evmA:
undetectable
2qx4B-5evmA:
undetectable		 2qx4A-5evmA:
17.51
2qx4B-5evmA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5evm FUSION GLYCOPROTEIN
F0
(Nipah
henipavirus) 		4 / 6 ILE A  59
PHE A 214
GLY A 236
GLY A 237
 None
None
MLI  A 611 ( 4.5A)
None
 0.74A 2qx6A-5evmA:
undetectable
2qx6B-5evmA:
undetectable		 2qx6A-5evmA:
17.51
2qx6B-5evmA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_A_FOLA401_0
(DIHYDROFOLATE
REDUCTASE)		 5evm FUSION GLYCOPROTEIN
F0
(Nipah
henipavirus) 		5 / 12 ILE A  27
LEU A 296
THR A  43
ILE A 293
THR A 357
 None
 1.12A 2w3bA-5evmA:
undetectable		 2w3bA-5evmA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_D_QPSD1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5evm FUSION GLYCOPROTEIN
F0
(Nipah
henipavirus) 		5 / 10 THR A 415
VAL A 436
ASN A 380
VAL A 382
GLY A 430
 None
None
None
None
NAG  A 601 (-3.2A)
 1.33A 2x2iD-5evmA:
undetectable		 2x2iD-5evmA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 5evm FUSION GLYCOPROTEIN
F0
(Nipah
henipavirus) 		5 / 12 PHE A 282
PRO A  52
GLY A 264
SER A 232
ILE A 266
 None
 1.36A 3iv6C-5evmA:
undetectable		 3iv6C-5evmA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)		 5evm FUSION GLYCOPROTEIN
F0
(Nipah
henipavirus) 		4 / 8 SER A 259
ASP A 252
LEU A  53
PRO A  52
 None
 1.21A 3jq7B-5evmA:
undetectable		 3jq7B-5evmA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 5evm FUSION GLYCOPROTEIN
F0
(Nipah
henipavirus) 		4 / 4 ASN A  84
SER A 208
LEU A 207
THR A  88
 None
 1.14A 4an2A-5evmA:
undetectable		 4an2A-5evmA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 5evm FUSION GLYCOPROTEIN
F0
(Nipah
henipavirus) 		4 / 4 VAL A 169
THR A 168
GLU A 163
GLU A 166
 None
 1.43A 4l78A-5evmA:
undetectable		 4l78A-5evmA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_2
(ASPARTYL PROTEASE)		 5evm FUSION GLYCOPROTEIN
F0
(Nipah
henipavirus) 		5 / 12 LEU A 172
ILE A 276
ILE A 266
GLY A 264
ILE A  59
 None
 0.94A 4q1yB-5evmA:
undetectable		 4q1yB-5evmA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 5evm FUSION GLYCOPROTEIN
F0
(Nipah
henipavirus) 		5 / 12 LEU A 218
VAL A 213
ILE A 276
VAL A 278
VAL A 280
 None
 1.03A 4y0pA-5evmA:
undetectable		 4y0pA-5evmA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_2
(HIV-1 PROTEASE)		 5evm FUSION GLYCOPROTEIN
F0
(Nipah
henipavirus) 		5 / 12 LEU A 172
ALA A 234
ILE A 276
ILE A  57
ILE A  59
 None
 0.84A 5e5kB-5evmA:
undetectable		 5e5kB-5evmA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 5evm FUSION GLYCOPROTEIN
F0
(Nipah
henipavirus) 		4 / 8 ILE A 323
THR A  43
VAL A  42
GLU A 295
 None
 1.02A 6fbvC-5evmA:
undetectable		 6fbvC-5evmA:
19.91