SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ewo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)		 5ewo STRUCTURAL PROTEIN
(Mamastrovirus
1) 		4 / 7 TYR A 588
PHE A 582
VAL A 543
GLY A 546
 None
 0.92A 11gsA-5ewoA:
undetectable		 11gsA-5ewoA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ewo STRUCTURAL PROTEIN
(Mamastrovirus
1) 		5 / 12 THR A 591
PHE A 438
LEU A 436
VAL A 434
THR A 482
 None
 1.04A 1q23B-5ewoA:
undetectable		 1q23B-5ewoA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 5ewo STRUCTURAL PROTEIN
(Mamastrovirus
1) 		4 / 8 TYR A 588
PHE A 582
VAL A 543
GLY A 546
 None
 0.90A 2gssA-5ewoA:
undetectable		 2gssA-5ewoA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 5ewo STRUCTURAL PROTEIN
(Mamastrovirus
1) 		4 / 8 TYR A 588
PHE A 582
VAL A 543
GLY A 546
 None
 0.90A 2gssB-5ewoA:
undetectable		 2gssB-5ewoA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5ewo STRUCTURAL PROTEIN
(Mamastrovirus
1) 		4 / 5 SER A 594
VAL A 609
SER A 537
VAL A 535
 None
 1.40A 2j9cA-5ewoA:
undetectable
2j9cB-5ewoA:
undetectable
2j9cC-5ewoA:
undetectable		 2j9cA-5ewoA:
18.06
2j9cB-5ewoA:
18.06
2j9cC-5ewoA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_B_VDYB6178_1
(VITAMIN D
HYDROXYLASE)		 5ewo STRUCTURAL PROTEIN
(Mamastrovirus
1) 		5 / 12 LEU A 590
ASN A 445
MET A 442
VAL A 434
LEU A 436
 None
 1.39A 3a51B-5ewoA:
undetectable		 3a51B-5ewoA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ewo STRUCTURAL PROTEIN
(Mamastrovirus
1) 		4 / 5 LEU A 626
GLN A 479
THR A 591
LEU A 569
 None
 1.25A 3ce6D-5ewoA:
undetectable		 3ce6D-5ewoA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 5ewo STRUCTURAL PROTEIN
(Mamastrovirus
1) 		5 / 9 TYR A 588
PHE A 582
VAL A 543
GLY A 586
GLY A 546
 None
 1.11A 3csjB-5ewoA:
undetectable		 3csjB-5ewoA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 5ewo STRUCTURAL PROTEIN
(Mamastrovirus
1) 		4 / 7 TYR A 588
PHE A 582
VAL A 543
GLY A 546
 None
 0.94A 3gssA-5ewoA:
undetectable		 3gssA-5ewoA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 5ewo STRUCTURAL PROTEIN
(Mamastrovirus
1) 		4 / 7 TYR A 588
PHE A 582
VAL A 543
GLY A 546
 None
 0.93A 3gssB-5ewoA:
undetectable		 3gssB-5ewoA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 5ewo STRUCTURAL PROTEIN
(Mamastrovirus
1) 		4 / 8 TYR A 588
PHE A 582
VAL A 543
GLY A 546
 None
 0.93A 3hjoA-5ewoA:
undetectable		 3hjoA-5ewoA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_A_ACRA720_1
(ALPHA-AMYLASE, SUSG)		 5ewo STRUCTURAL PROTEIN
(Mamastrovirus
1) 		4 / 7 TYR A 519
GLU A 498
TRP A 489
LEU A 540
 None
 1.35A 3k8mA-5ewoA:
undetectable		 3k8mA-5ewoA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 5ewo STRUCTURAL PROTEIN
(Mamastrovirus
1) 		5 / 10 TYR A 588
PHE A 582
VAL A 543
GLY A 586
GLY A 546
 None
 1.08A 3km6A-5ewoA:
undetectable		 3km6A-5ewoA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 5ewo STRUCTURAL PROTEIN
(Mamastrovirus
1) 		5 / 9 TYR A 588
PHE A 582
VAL A 543
GLY A 586
GLY A 546
 None
 1.09A 3kmoA-5ewoA:
undetectable		 3kmoA-5ewoA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 5ewo STRUCTURAL PROTEIN
(Mamastrovirus
1) 		4 / 7 TYR A 588
PHE A 582
VAL A 543
GLY A 546
 None
 0.94A 3kmoB-5ewoA:
undetectable		 3kmoB-5ewoA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 5ewo STRUCTURAL PROTEIN
(Mamastrovirus
1) 		4 / 8 TYR A 588
PHE A 582
VAL A 543
GLY A 546
 None
 0.91A 3n9jA-5ewoA:
undetectable		 3n9jA-5ewoA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 5ewo STRUCTURAL PROTEIN
(Mamastrovirus
1) 		5 / 8 TYR A 588
PHE A 582
VAL A 543
GLY A 586
GLY A 546
 None
 1.10A 3n9jB-5ewoA:
undetectable		 3n9jB-5ewoA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 5ewo STRUCTURAL PROTEIN
(Mamastrovirus
1) 		4 / 6 THR A 529
ASN A 531
GLY A 598
ASP A 597
 None
 1.20A 3w9tE-5ewoA:
undetectable		 3w9tE-5ewoA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5ewo STRUCTURAL PROTEIN
(Mamastrovirus
1) 		4 / 5 PHE A 438
LEU A 626
GLY A 480
ILE A 484
 None
 1.01A 5ik1A-5ewoA:
undetectable		 5ik1A-5ewoA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ewo STRUCTURAL PROTEIN
(Mamastrovirus
1) 		3 / 3 TYR A 557
ARG A 572
THR A 613
 None
 0.92A 5z84J-5ewoA:
undetectable		 5z84J-5ewoA:
12.22