SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ewy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5ewy PUTATIVE
ADP-RIBOSYLTRANSFERA
SE SCABIN
(Streptomyces
scabiei) 		4 / 7 ARG A  77
SER A 117
GLN A 158
GLU A 160
 5TQ  A 301 (-2.9A)
5TQ  A 301 (-3.6A)
5TQ  A 301 (-3.0A)
5TQ  A 301 (-2.9A)
 0.58A 2c8aA-5ewyA:
3.0		 2c8aA-5ewyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5ewy PUTATIVE
ADP-RIBOSYLTRANSFERA
SE SCABIN
(Streptomyces
scabiei) 		4 / 7 VAL A 143
TYR A 106
TYR A 115
ILE A 149
 None
 1.18A 2xz5B-5ewyA:
undetectable
2xz5E-5ewyA:
undetectable		 2xz5B-5ewyA:
19.25
2xz5E-5ewyA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 5ewy PUTATIVE
ADP-RIBOSYLTRANSFERA
SE SCABIN
(Streptomyces
scabiei) 		4 / 5 ILE A 137
THR A 118
THR A 119
PHE A 163
 None
None
5TQ  A 301 ( 3.8A)
None
 1.06A 3snfA-5ewyA:
undetectable		 3snfA-5ewyA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 5ewy PUTATIVE
ADP-RIBOSYLTRANSFERA
SE SCABIN
(Streptomyces
scabiei) 		4 / 5 GLY A 165
VAL A  57
PRO A 114
TYR A 106
 None
 1.15A 4grkA-5ewyA:
undetectable		 4grkA-5ewyA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)		 5ewy PUTATIVE
ADP-RIBOSYLTRANSFERA
SE SCABIN
(Streptomyces
scabiei) 		3 / 3 TYR A 133
GLY A  82
PRO A  83
 None
 0.59A 4qwpA-5ewyA:
undetectable		 4qwpA-5ewyA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_A_SALA201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 5ewy PUTATIVE
ADP-RIBOSYLTRANSFERA
SE SCABIN
(Streptomyces
scabiei) 		4 / 5 VAL A  59
PRO A 114
GLY A 165
TYR A 115
 None
 1.45A 5x80A-5ewyA:
undetectable
5x80B-5ewyA:
undetectable		 5x80A-5ewyA:
19.29
5x80B-5ewyA:
19.29