SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5exc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWJ_A_CAMA418_0
(CYTOCHROME P450-CAM)		 5exc GREEN FLUORESCENT
PROTEIN
(Dendronephthya
sp.
SSAL-2002) 		5 / 9 PHE I  79
TYR I 177
THR I 175
THR I  69
VAL I 191
 None
 1.46A 1iwjA-5excI:
undetectable		 1iwjA-5excI:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 5exc GREEN FLUORESCENT
PROTEIN
(Dendronephthya
sp.
SSAL-2002) 		5 / 10 PHE I  79
TYR I 177
THR I 175
THR I  69
VAL I 191
 None
 1.44A 1o76A-5excI:
undetectable		 1o76A-5excI:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 5exc GREEN FLUORESCENT
PROTEIN
(Dendronephthya
sp.
SSAL-2002) 		5 / 9 PHE I  79
TYR I 177
THR I 175
THR I  69
VAL I 191
 None
 1.46A 1t86B-5excI:
undetectable		 1t86B-5excI:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 5exc GREEN FLUORESCENT
PROTEIN
(Dendronephthya
sp.
SSAL-2002) 		4 / 4 ASP A  55
LEU I 162
LEU I 137
LEU I 161
 None
 1.20A 1u18A-5excA:
undetectable		 1u18A-5excA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 5exc GREEN FLUORESCENT
PROTEIN
(Dendronephthya
sp.
SSAL-2002) 		5 / 9 PHE I  79
TYR I 177
THR I 175
THR I  69
VAL I 191
 None
 1.43A 2a1nB-5excI:
undetectable		 2a1nB-5excI:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5exc GREEN FLUORESCENT
PROTEIN
(Dendronephthya
sp.
SSAL-2002) 		4 / 7 ARG I  91
SER I 105
ARG I  66
GLN I 116
 RC7  I  64 ( 2.7A)
RC7  I  64 ( 4.4A)
RC7  I  64 ( 4.3A)
NLW  A  61 ( 4.4A)
 1.06A 2c8aA-5excI:
undetectable		 2c8aA-5excI:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_0
(UNCHARACTERIZED
PROTEIN PH0793)		 5exc GREEN FLUORESCENT
PROTEIN
(Dendronephthya
sp.
SSAL-2002) 		5 / 12 PHE I  68
GLY I 213
HIS I 212
ASN I  65
PHE I 114
 None
 0.85A 3a25A-5excI:
undetectable		 3a25A-5excI:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 5exc GREEN FLUORESCENT
PROTEIN
(Dendronephthya
sp.
SSAL-2002) 		3 / 3 HIS I 212
GLU I 211
HIS I 193
 None
RC7  I  64 ( 3.4A)
RC7  I  64 ( 3.6A)
 0.83A 3ba0A-5excI:
undetectable		 3ba0A-5excI:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5exc GREEN FLUORESCENT
PROTEIN
(Dendronephthya
sp.
SSAL-2002) 		5 / 9 PHE I  79
TYR I 177
THR I 175
THR I  69
VAL I 191
 None
 1.44A 3cppA-5excI:
undetectable		 3cppA-5excI:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_B_DEXB247_1
(GLUCOCORTICOID
RECEPTOR 2)		 5exc GREEN FLUORESCENT
PROTEIN
(Dendronephthya
sp.
SSAL-2002) 		5 / 12 GLY A  20
MET A  14
CYH I 101
VAL I 131
PHE I 125
 None
NLW  A  61 ( 3.8A)
None
None
None
 1.45A 3gn8B-5excA:
undetectable		 3gn8B-5excA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_C_DXCC92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5exc GREEN FLUORESCENT
PROTEIN
(Dendronephthya
sp.
SSAL-2002) 		4 / 4 VAL I 118
PHE I 115
PHE I 114
VAL I  67
 None
 1.16A 3rv5C-5excI:
undetectable
3rv5D-5excI:
undetectable		 3rv5C-5excI:
18.01
3rv5D-5excI:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6V_E_RBFE201_1
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT B
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT E)		 5exc GREEN FLUORESCENT
PROTEIN
(Dendronephthya
sp.
SSAL-2002) 		4 / 5 HIS I 212
GLU A  35
VAL I 214
LYS I  70
 None
 1.38A 4p6vB-5excI:
undetectable
4p6vE-5excI:
undetectable		 4p6vB-5excI:
16.63
4p6vE-5excI:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5exc GREEN FLUORESCENT
PROTEIN
GREEN FLUORESCENT
PROTEIN
(Dendronephthya
sp.
SSAL-2002;
Dendronephthya
sp.
SSAL-2002) 		4 / 8 SER A  53
PRO I 130
LEU I 161
LEU I 163
 None
 1.18A 5dzkd-5excA:
undetectable
5dzkr-5excA:
undetectable		 5dzkd-5excA:
14.22
5dzkr-5excA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 5exc GREEN FLUORESCENT
PROTEIN
(Dendronephthya
sp.
SSAL-2002) 		5 / 10 TYR I 177
ARG I  91
VAL I  67
TYR I  71
ILE I 195
 None
RC7  I  64 ( 2.7A)
None
None
RC7  I  64 ( 4.2A)
 1.36A 5hw8C-5excI:
undetectable
5hw8H-5excI:
undetectable		 5hw8C-5excI:
19.14
5hw8H-5excI:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W8A_A_SAMA300_0
(AUTOINDUCER SYNTHASE)		 5exc GREEN FLUORESCENT
PROTEIN
GREEN FLUORESCENT
PROTEIN
(Dendronephthya
sp.
SSAL-2002;
Dendronephthya
sp.
SSAL-2002) 		5 / 12 THR A  58
MET I 159
PHE I 173
ILE I 157
THR I 175
 None
RC7  I  64 ( 3.3A)
None
RC7  I  64 ( 4.5A)
None
 1.28A 5w8aA-5excA:
undetectable		 5w8aA-5excA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WHY_A_SAMA504_0
(RADICAL SAM DOMAIN
PROTEIN)		 5exc GREEN FLUORESCENT
PROTEIN
(Dendronephthya
sp.
SSAL-2002) 		5 / 11 TYR I  71
THR I 175
ARG I  66
THR I  69
VAL I 214
 None
None
RC7  I  64 ( 4.3A)
None
None
 1.45A 5whyA-5excI:
undetectable		 5whyA-5excI:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNA_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 5exc GREEN FLUORESCENT
PROTEIN
(Dendronephthya
sp.
SSAL-2002) 		3 / 3 ARG I 216
LYS I 145
TYR I 188
 None
 1.36A 6gnaA-5excI:
undetectable		 6gnaA-5excI:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNB_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 5exc GREEN FLUORESCENT
PROTEIN
(Dendronephthya
sp.
SSAL-2002) 		3 / 3 ARG I 216
LYS I 145
TYR I 188
 None
 1.36A 6gnbA-5excI:
undetectable		 6gnbA-5excI:
21.36