SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ey2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 5ey2 GTP-SENSING
TRANSCRIPTIONAL
PLEIOTROPIC
REPRESSOR CODY
(Bacillus
cereus) 		4 / 8 SER A  28
LEU A 126
VAL A 150
GLY A 124
 None
 0.68A 3dcjB-5ey2A:
undetectable		 3dcjB-5ey2A:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 5ey2 GTP-SENSING
TRANSCRIPTIONAL
PLEIOTROPIC
REPRESSOR CODY
(Bacillus
cereus) 		4 / 8 GLN A 133
ARG A 130
LEU A 142
ILE A  35
 None
 0.92A 3nbqB-5ey2A:
undetectable		 3nbqB-5ey2A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		 5ey2 GTP-SENSING
TRANSCRIPTIONAL
PLEIOTROPIC
REPRESSOR CODY
(Bacillus
cereus) 		4 / 6 ASP A 139
GLU A 134
LEU A 136
GLU A  36
 None
 1.17A 3w9tF-5ey2A:
undetectable		 3w9tF-5ey2A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5ey2 GTP-SENSING
TRANSCRIPTIONAL
PLEIOTROPIC
REPRESSOR CODY
(Bacillus
cereus) 		4 / 6 ILE A 113
THR A 125
VAL A  91
SER A  78
 None
 0.99A 4iaqA-5ey2A:
undetectable		 4iaqA-5ey2A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 5ey2 GTP-SENSING
TRANSCRIPTIONAL
PLEIOTROPIC
REPRESSOR CODY
(Bacillus
cereus) 		5 / 12 ASN A 219
ALA A 186
ILE A 206
ALA A 207
ILE A 190
 None
 0.98A 5eypB-5ey2A:
undetectable		 5eypB-5ey2A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_B_LOCB504_2
(TUBULIN BETA CHAIN)		 5ey2 GTP-SENSING
TRANSCRIPTIONAL
PLEIOTROPIC
REPRESSOR CODY
(Bacillus
cereus) 		6 / 12 LEU A 221
ASN A 219
ALA A 186
ILE A 206
ALA A 207
ILE A 190
 None
 1.25A 5xiwB-5ey2A:
undetectable		 5xiwB-5ey2A:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_2
(TUBULIN BETA CHAIN)		 5ey2 GTP-SENSING
TRANSCRIPTIONAL
PLEIOTROPIC
REPRESSOR CODY
(Bacillus
cereus) 		5 / 12 ASN A 219
ALA A 186
ILE A 206
ALA A 207
ILE A 190
 None
 0.97A 5xiwD-5ey2A:
undetectable		 5xiwD-5ey2A:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEH_A_RPTA601_1
(SCAFFOLD PROTEIN D13)		 5ey2 GTP-SENSING
TRANSCRIPTIONAL
PLEIOTROPIC
REPRESSOR CODY
(Bacillus
cereus) 		5 / 10 GLU A 183
SER A 232
VAL A 244
PHE A 191
PHE A 249
 None
 1.33A 6behA-5ey2A:
undetectable
6behB-5ey2A:
undetectable
6behC-5ey2A:
undetectable		 6behA-5ey2A:
17.32
6behB-5ey2A:
17.32
6behC-5ey2A:
17.32