SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ey7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
5 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
ASP A 266
None
0.43A 1bx4A-5ey7A:
30.6
1bx4A-5ey7A:
26.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
5 / 12 LEU A 318
PHE A 268
GLY A 299
ALA A 300
GLY A 239
None
1.14A 1fe2A-5ey7A:
undetectable
1fe2A-5ey7A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
5 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
ASP A 266
None
0.39A 1liiA-5ey7A:
27.1
1liiA-5ey7A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
5 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
ASP A 266
None
0.48A 1likA-5ey7A:
30.0
1likA-5ey7A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
5 / 12 GLY A 265
ASN A  49
ASP A 260
ILE A  32
VAL A 102
None
None
NA  A 401 (-3.5A)
None
None
1.19A 1r30A-5ey7A:
2.4
1r30A-5ey7A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
PHE A 115
ASP A 266
None
0.94A 2c49A-5ey7A:
32.6
2c49A-5ey7A:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
5 / 7 ASP A  30
GLY A  44
GLY A  45
ASN A  49
PHE A 115
None
0.75A 2c49B-5ey7A:
32.1
2c49B-5ey7A:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQY_A_ADNA400_1
(MEMBRANE LIPOPROTEIN
TMPC)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
5 / 12 ASP A 260
PHE A 113
GLY A  44
VAL A 101
ASP A  30
NA  A 401 (-3.5A)
None
None
None
None
1.47A 2fqyA-5ey7A:
4.3
2fqyA-5ey7A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_1
(ADENOSINE KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
GLY A 263
ASP A 266
None
0.41A 2pkkA-5ey7A:
30.2
2pkkA-5ey7A:
26.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ALA A  27
GLY A  44
GLY A  45
ASN A  49
GLY A 263
ASP A 266
None
1.37A 2pkmA-5ey7A:
29.9
2pkmA-5ey7A:
26.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
GLY A 263
ASP A 266
None
0.43A 2pkmA-5ey7A:
29.9
2pkmA-5ey7A:
26.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WQ5_A_MIYA1120_1
(PHOSPHOLIPASE A2,
ACIDIC)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
4 / 7 LEU A 322
ALA A 295
GLY A 299
PHE A 321
None
0.97A 2wq5A-5ey7A:
undetectable
2wq5A-5ey7A:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A301_1
(THIOPURINE
S-METHYLTRANSFERASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
4 / 6 GLY A 299
ALA A 302
LEU A 318
PRO A 313
None
NA  A 401 (-4.8A)
None
None
0.94A 3bgdA-5ey7A:
3.5
3bgdA-5ey7A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B301_1
(THIOPURINE
S-METHYLTRANSFERASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
4 / 8 PHE A  75
GLY A  73
VAL A  67
LEU A  90
None
1.10A 3bgdB-5ey7A:
3.4
3bgdB-5ey7A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
GLY A 263
ASP A 266
None
0.39A 3uboA-5ey7A:
33.5
3uboA-5ey7A:
25.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.54A 3uboB-5ey7A:
34.5
3uboB-5ey7A:
25.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
5 / 10 VAL A  52
GLY A  45
ALA A  48
ALA A  27
THR A  79
None
1.18A 3ucjB-5ey7A:
undetectable
3ucjB-5ey7A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
7 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
VAL A 101
GLY A 263
ASP A 266
None
0.56A 3uq6A-5ey7A:
31.5
3uq6A-5ey7A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
7 / 12 ASP A  30
GLY A  45
ALA A  46
ASN A  49
VAL A 101
GLY A 263
ASP A 266
None
0.56A 3uq6B-5ey7A:
30.5
3uq6B-5ey7A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
7 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
VAL A 101
GLY A 263
ASP A 266
None
0.59A 3vaqA-5ey7A:
31.4
3vaqA-5ey7A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
7 / 12 ASP A  30
GLY A  45
ALA A  46
ASN A  49
VAL A 101
GLY A 263
ASP A 266
None
0.59A 3vaqB-5ey7A:
29.9
3vaqB-5ey7A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
7 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
VAL A 101
GLY A 263
ASP A 266
None
0.56A 3vasA-5ey7A:
31.3
3vasA-5ey7A:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
7 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
VAL A 101
GLY A 263
ASP A 266
None
0.54A 3vasB-5ey7A:
22.0
3vasB-5ey7A:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
5 / 11 THR A 155
ALA A 158
LEU A 139
PHE A 133
SER A 151
None
1.08A 4claA-5ey7A:
undetectable
4claA-5ey7A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
7 / 12 ASP A  30
GLY A  44
ALA A  46
ASN A  49
VAL A 101
GLY A 263
ASP A 266
None
0.70A 4dc3A-5ey7A:
29.6
4dc3A-5ey7A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
7 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
VAL A 101
GLY A 263
ASP A 266
None
0.58A 4dc3B-5ey7A:
31.4
4dc3B-5ey7A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.45A 4e3aA-5ey7A:
34.7
4e3aA-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
7 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
GLY A 263
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
None
0.45A 4e3aB-5ey7A:
34.6
4e3aB-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.52A 4jksA-5ey7A:
34.6
4jksA-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.51A 4jksB-5ey7A:
34.7
4jksB-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.54A 4jkuA-5ey7A:
32.1
4jkuA-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.54A 4jkuB-5ey7A:
34.6
4jkuB-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.55A 4k8cA-5ey7A:
32.0
4k8cA-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.55A 4k8cB-5ey7A:
34.4
4k8cB-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.52A 4k8kA-5ey7A:
34.6
4k8kA-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.52A 4k8kB-5ey7A:
34.6
4k8kB-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.53A 4k8pA-5ey7A:
34.8
4k8pA-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.53A 4k8pB-5ey7A:
34.5
4k8pB-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.53A 4k8tA-5ey7A:
34.5
4k8tA-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.53A 4k8tB-5ey7A:
34.5
4k8tB-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.52A 4k93A-5ey7A:
34.7
4k93A-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.52A 4k93B-5ey7A:
34.7
4k93B-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.52A 4k9cA-5ey7A:
34.7
4k9cA-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.51A 4k9cB-5ey7A:
34.6
4k9cB-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.54A 4k9iA-5ey7A:
34.6
4k9iA-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.54A 4k9iB-5ey7A:
34.7
4k9iB-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.54A 4kadA-5ey7A:
34.7
4kadA-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.54A 4kadB-5ey7A:
32.0
4kadB-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.53A 4kahA-5ey7A:
32.1
4kahA-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.53A 4kahB-5ey7A:
34.7
4kahB-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.54A 4kalA-5ey7A:
34.6
4kalA-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.54A 4kalB-5ey7A:
34.5
4kalB-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.52A 4kanA-5ey7A:
32.1
4kanA-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.50A 4kanB-5ey7A:
34.7
4kanB-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.53A 4kbeA-5ey7A:
32.1
4kbeA-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.52A 4kbeB-5ey7A:
32.2
4kbeB-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.52A 4lbgA-5ey7A:
34.6
4lbgA-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.52A 4lbgB-5ey7A:
34.6
4lbgB-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.54A 4lbxA-5ey7A:
34.6
4lbxA-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.52A 4lbxB-5ey7A:
34.7
4lbxB-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.52A 4lc4A-5ey7A:
34.6
4lc4A-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.53A 4lc4B-5ey7A:
34.5
4lc4B-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.52A 4lcaA-5ey7A:
34.7
4lcaA-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
THR A 262
ASP A 266
None
None
None
None
NA  A 401 (-4.9A)
None
0.54A 4lcaB-5ey7A:
34.5
4lcaB-5ey7A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
5 / 12 ASP A  30
GLY A  45
ASN A  49
GLY A 263
ASP A 266
None
0.72A 4n09A-5ey7A:
31.2
4n09A-5ey7A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
5 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
ASP A 266
None
0.44A 4n09B-5ey7A:
31.1
4n09B-5ey7A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
5 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
ASP A 266
None
0.44A 4n09C-5ey7A:
31.2
4n09C-5ey7A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
5 / 12 ASP A  30
GLY A  45
ASN A  49
GLY A 263
ASP A 266
None
0.80A 4n09C-5ey7A:
31.2
4n09C-5ey7A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
5 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
ASP A 266
None
0.45A 4n09D-5ey7A:
31.1
4n09D-5ey7A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
5 / 12 ASP A  30
GLY A  45
ASN A  49
GLY A 263
ASP A 266
None
0.82A 4n09D-5ey7A:
31.1
4n09D-5ey7A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_1
(ADENOSINE KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
5 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
ASP A 266
None
0.42A 4ubeA-5ey7A:
30.1
4ubeA-5ey7A:
26.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
4 / 5 PHE A 124
PRO A  94
VAL A  95
ALA A 121
None
1.35A 4w5oA-5ey7A:
undetectable
4w5oA-5ey7A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDQ_A_BEZA306_0
(GLYCOSIDE HYDROLASE
FAMILY PROTEIN)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
3 / 3 ARG A 275
ASP A 290
TRP A 294
None
1.04A 4xdqA-5ey7A:
undetectable
4xdqA-5ey7A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA407_0
(FAD:PROTEIN FMN
TRANSFERASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
3 / 3 ASP A  30
GLY A 307
ASP A 260
None
NA  A 401 (-4.3A)
NA  A 401 (-3.5A)
0.69A 4xdtA-5ey7A:
undetectable
4xdtA-5ey7A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
4 / 7 ASN A 296
LYS A 293
TYR A 274
LEU A 273
None
1.19A 4yv5B-5ey7A:
undetectable
4yv5B-5ey7A:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
5 / 12 PHE A 226
ILE A 223
VAL A 190
GLY A 212
PHE A 202
None
1.04A 5byjA-5ey7A:
undetectable
5byjA-5ey7A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
5 / 12 GLY A 307
LEU A  80
PHE A  63
GLY A  65
PHE A  75
NA  A 401 (-4.3A)
None
None
None
None
1.12A 5eskA-5ey7A:
undetectable
5eskA-5ey7A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_1
(CYP51 VARIANT1)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
5 / 12 GLY A 307
LEU A  80
PHE A  63
GLY A  65
PHE A  75
NA  A 401 (-4.3A)
None
None
None
None
1.25A 5fsaB-5ey7A:
undetectable
5fsaB-5ey7A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
6 / 12 ASP A  30
GLY A  44
GLY A  45
ASN A  49
GLY A 263
ASP A 266
None
0.45A 5kb5A-5ey7A:
30.6
5kb5A-5ey7A:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
5 / 12 ASP A  70
GLY A  73
MET A  76
LEU A  80
ALA A  48
None
1.09A 5kbwA-5ey7A:
undetectable
5kbwA-5ey7A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
5 / 12 ASP A  70
GLY A  73
MET A  76
LEU A  80
ALA A  48
None
1.20A 5kc4E-5ey7A:
undetectable
5kc4E-5ey7A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
4 / 5 ALA A 240
VAL A 242
PHE A 268
ILE A 288
None
1.00A 5of1B-5ey7A:
undetectable
5of1B-5ey7A:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
4 / 5 ASN A 174
ASP A 266
ASN A  49
ASP A  30
None
1.18A 5vooA-5ey7A:
2.4
5vooA-5ey7A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
4 / 5 ASN A 174
ASP A 266
ASN A  49
ASP A  30
None
1.17A 5vooC-5ey7A:
2.3
5vooC-5ey7A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
4 / 5 ASN A 174
ASP A 266
ASN A  49
ASP A  30
None
1.18A 5vooE-5ey7A:
2.5
5vooE-5ey7A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_A_SAMA401_0
(O-METHYLTRANSFERASE)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
5 / 12 ARG A 176
GLY A  25
SER A  61
VAL A  28
ASP A 266
None
1.09A 6clxA-5ey7A:
4.4
6clxA-5ey7A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5ey7 FRUCTOKINASE
(Vibrio
cholerae)
4 / 5 LEU A 125
GLN A 126
PHE A 124
PHE A  63
None
1.37A 6nmpP-5ey7A:
undetectable
6nmpW-5ey7A:
undetectable
6nmpP-5ey7A:
21.32
6nmpW-5ey7A:
12.70