SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ey8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_1
(PROTEASE)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		4 / 7 ASP A 303
GLY A 330
ALA A 289
ILE A 264
 None
 0.74A 1n49A-5ey8A:
undetectable		 1n49A-5ey8A:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 PHE A 286
LEU A 267
VAL A 307
PHE A 334
ALA A 309
 None
 1.32A 1q23A-5ey8A:
undetectable
1q23B-5ey8A:
undetectable		 1q23A-5ey8A:
13.88
1q23B-5ey8A:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_D_FUAD705_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 PHE A 286
LEU A 267
VAL A 307
PHE A 334
ALA A 309
 None
 1.29A 1q23D-5ey8A:
undetectable
1q23E-5ey8A:
undetectable		 1q23D-5ey8A:
13.88
1q23E-5ey8A:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 THR A 133
TYR A  90
PHE A  94
LEU A 123
VAL A 122
 None
 1.41A 1q23J-5ey8A:
undetectable		 1q23J-5ey8A:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		3 / 3 ALA A 472
VAL A 402
TRP A 421
 None
 0.96A 1tkqA-5ey8A:
undetectable		 1tkqA-5ey8A:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLU A 347
PHE A 442
ILE A 480
LEU A 478
GLY A 344
 None
None
5SV  A 701 (-3.6A)
None
5SV  A 701 (-3.6A)
 1.29A 2e7fB-5ey8A:
undetectable		 2e7fB-5ey8A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 THR A 135
THR A 134
THR A 133
ALA A 138
ALA A 161
 None
 1.12A 2f162-5ey8A:
undetectable		 2f162-5ey8A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 THR A 135
THR A 134
THR A 133
ALA A 138
ALA A 161
 None
 1.12A 2f16N-5ey8A:
undetectable		 2f16N-5ey8A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JST_A_HLTA101_1
(FOUR-ALPHA-HELIX
BUNDLE)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 ALA A 285
TRP A 226
LEU A 267
ALA A 289
 None
 1.07A 2jstA-5ey8A:
undetectable
2jstB-5ey8A:
undetectable		 2jstA-5ey8A:
6.94
2jstB-5ey8A:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLU A 347
PHE A 442
ILE A 480
LEU A 478
GLY A 344
 None
None
5SV  A 701 (-3.6A)
None
5SV  A 701 (-3.6A)
 1.33A 2ogyB-5ey8A:
undetectable		 2ogyB-5ey8A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		4 / 6 ILE A 489
SER A 520
ARG A 608
ARG A 605
 None
 1.01A 2q72A-5ey8A:
undetectable		 2q72A-5ey8A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_G_RBFG200_1
(DODECIN)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		4 / 8 ARG A  62
GLN A  58
ARG A  52
THR A 135
 None
 1.30A 2vxaF-5ey8A:
undetectable
2vxaG-5ey8A:
undetectable
2vxaI-5ey8A:
undetectable		 2vxaF-5ey8A:
7.78
2vxaG-5ey8A:
7.78
2vxaI-5ey8A:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_B_VD3B2001_1
(VITAMIN D
HYDROXYLASE)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 ILE A 103
LEU A 204
LEU A 184
ILE A 199
THR A 429
 None
 1.25A 3a50B-5ey8A:
undetectable		 3a50B-5ey8A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_C_VD3C2001_1
(VITAMIN D
HYDROXYLASE)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 ILE A 103
LEU A 204
LEU A 184
ILE A 199
THR A 429
 None
 1.22A 3a50C-5ey8A:
undetectable		 3a50C-5ey8A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_E_VD3E2001_1
(VITAMIN D
HYDROXYLASE)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ILE A 103
LEU A 204
LEU A 184
ILE A 199
THR A 429
 None
 1.22A 3a50E-5ey8A:
undetectable		 3a50E-5ey8A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_1
(HIV-1 PROTEASE)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY A 471
ALA A 472
ASP A 414
VAL A 366
ILE A 376
 None
 1.04A 3d1zA-5ey8A:
undetectable		 3d1zA-5ey8A:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAT_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ALA A 281
VAL A 310
ILE A 264
LEU A 304
PHE A 325
 None
 1.18A 3datA-5ey8A:
undetectable		 3datA-5ey8A:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_D_TOPD200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 9 ALA A 281
VAL A 310
ILE A 264
LEU A 304
PHE A 325
 None
 1.19A 3fl9D-5ey8A:
undetectable		 3fl9D-5ey8A:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_H_TOPH200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 9 ALA A 281
VAL A 310
ILE A 264
LEU A 304
PHE A 325
 None
 1.13A 3fl9H-5ey8A:
undetectable		 3fl9H-5ey8A:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		4 / 7 VAL A  66
VAL A  80
ASN A  63
GLY A  96
 None
 1.10A 3kmoB-5ey8A:
undetectable		 3kmoB-5ey8A:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 THR A 135
THR A 134
THR A 133
ALA A 138
ALA A 161
 None
 1.16A 3mg02-5ey8A:
undetectable
3mg0V-5ey8A:
undetectable		 3mg02-5ey8A:
15.08
3mg0V-5ey8A:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 THR A 135
THR A 134
THR A 133
ALA A 138
ALA A 161
 None
 1.17A 3mg0N-5ey8A:
undetectable		 3mg0N-5ey8A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_2
(PROTEASE)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		3 / 3 ARG A 368
VAL A 417
THR A 481
 None
 0.80A 3ndtA-5ey8A:
undetectable		 3ndtA-5ey8A:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 TYR A 186
LEU A 184
GLY A 196
THR A 195
CYH A 126
 None
 1.28A 3okxA-5ey8A:
undetectable		 3okxA-5ey8A:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_1
(GLYCINE
N-METHYLTRANSFERASE)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		3 / 3 LEU A 227
HIS A 231
MET A 233
 None
5SV  A 701 (-4.0A)
5SV  A 701 ( 3.7A)
 0.90A 3thrD-5ey8A:
2.1		 3thrD-5ey8A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 VAL A  80
GLY A  96
ALA A  97
ALA A 100
THR A  74
 None
 0.95A 3ucjA-5ey8A:
undetectable		 3ucjA-5ey8A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 VAL A  80
GLY A  96
ALA A  97
ALA A 100
THR A  74
 None
 0.95A 3ucjB-5ey8A:
undetectable		 3ucjB-5ey8A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_2
(HIV-1 PROTEASE)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		4 / 7 ASP A 585
GLY A 614
VAL A 521
VAL A 550
 None
 0.81A 3ufnB-5ey8A:
undetectable		 3ufnB-5ey8A:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLU A 347
PHE A 442
ILE A 480
LEU A 478
GLY A 344
 None
None
5SV  A 701 (-3.6A)
None
5SV  A 701 (-3.6A)
 1.27A 4djfB-5ey8A:
undetectable		 4djfB-5ey8A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A  98
GLY A  96
LEU A 132
VAL A 105
THR A  74
 None
 1.09A 4ok1A-5ey8A:
undetectable		 4ok1A-5ey8A:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A  98
GLY A  96
LEU A 132
VAL A 105
THR A  74
 None
 1.07A 4okbA-5ey8A:
undetectable		 4okbA-5ey8A:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A  98
GLY A  96
LEU A 132
VAL A 105
THR A  74
 None
 1.09A 4okxA-5ey8A:
undetectable		 4okxA-5ey8A:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A  98
GLY A  96
LEU A 132
VAL A 105
THR A  74
 None
 0.98A 4olmA-5ey8A:
undetectable		 4olmA-5ey8A:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 TYR A  38
PHE A  59
GLU A  26
VAL A  25
ILE A 236
 None
 1.28A 4qt3A-5ey8A:
undetectable		 4qt3A-5ey8A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ALA A 401
GLY A 396
GLN A 210
ALA A 346
GLY A 344
 None
None
None
5SV  A 701 (-4.7A)
5SV  A 701 (-3.6A)
 1.09A 4r29A-5ey8A:
undetectable		 4r29A-5ey8A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ALA A 401
GLY A 396
GLN A 210
ALA A 346
GLY A 344
 None
None
None
5SV  A 701 (-4.7A)
5SV  A 701 (-3.6A)
 1.10A 4r29D-5ey8A:
undetectable		 4r29D-5ey8A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		4 / 6 ASP A  89
ALA A 161
THR A 134
THR A 135
 None
 1.47A 4w5qA-5ey8A:
2.5		 4w5qA-5ey8A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		4 / 6 ASP A  89
ALA A 161
THR A 134
THR A 135
 None
 1.50A 4w5rA-5ey8A:
2.6		 4w5rA-5ey8A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		4 / 6 ASP A  89
ALA A 161
THR A 134
THR A 135
 None
 1.48A 4z4cA-5ey8A:
2.2		 4z4cA-5ey8A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		4 / 6 ASP A  89
ALA A 161
THR A 134
THR A 135
 None
 1.46A 4z4fA-5ey8A:
2.1		 4z4fA-5ey8A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 ASP A  89
ALA A 161
THR A 134
THR A 135
 None
 1.48A 4z4gA-5ey8A:
2.3		 4z4gA-5ey8A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		4 / 6 ASP A  89
ALA A 161
THR A 134
THR A 135
 None
 1.48A 4z4iA-5ey8A:
2.2		 4z4iA-5ey8A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		4 / 8 LEU A 267
LEU A 311
THR A 237
GLN A  86
 None
5SV  A 701 (-4.2A)
5SV  A 701 (-3.3A)
None
 1.18A 5hbsA-5ey8A:
undetectable		 5hbsA-5ey8A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 THR A 135
THR A 134
THR A 133
ALA A 138
ALA A 161
 None
 1.09A 5lf7V-5ey8A:
undetectable
5lf7b-5ey8A:
undetectable		 5lf7V-5ey8A:
16.67
5lf7b-5ey8A:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 THR A 135
THR A 134
THR A 133
ALA A 138
ALA A 161
 None
 1.09A 5lf7H-5ey8A:
undetectable
5lf7N-5ey8A:
undetectable		 5lf7H-5ey8A:
16.67
5lf7N-5ey8A:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_A_PFLA412_1
(PROTON-GATED ION
CHANNEL)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 ILE A 403
ILE A 420
VAL A 417
THR A 481
ILE A 480
 None
None
None
None
5SV  A 701 (-3.6A)
 1.33A 5mzrA-5ey8A:
undetectable		 5mzrA-5ey8A:
10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_C_PFLC409_1
(PROTON-GATED ION
CHANNEL)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 ILE A 403
ILE A 420
VAL A 417
THR A 481
ILE A 480
 None
None
None
None
5SV  A 701 (-3.6A)
 1.33A 5mzrC-5ey8A:
undetectable		 5mzrC-5ey8A:
10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 9 ILE A 403
ILE A 420
VAL A 417
THR A 481
ILE A 480
 None
None
None
None
5SV  A 701 (-3.6A)
 1.34A 5mzrD-5ey8A:
undetectable		 5mzrD-5ey8A:
10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		3 / 3 ALA A 100
GLN A  72
THR A  74
 None
 0.75A 5n0oA-5ey8A:
undetectable		 5n0oA-5ey8A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_0
(SERUM ALBUMIN)		 5ey8 ACYL-COA SYNTHASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A 204
ILE A 199
LEU A  88
LEU A 235
PHE A 248
 None
 1.18A 6a7pA-5ey8A:
undetectable		 6a7pA-5ey8A:
21.54