SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ey9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		4 / 7 VAL A 351
ASN A 212
ASP A 397
LYS A  12
 None
 1.34A 1hwiC-5ey9A:
3.0		 1hwiC-5ey9A:
22.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		4 / 7 VAL A 351
ASN A 212
ASP A 397
LYS A  12
 None
 1.34A 1hwiD-5ey9A:
3.5		 1hwiD-5ey9A:
22.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOZ_A_CIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 12 GLN A 184
ILE A 198
PHE A  95
LEU A  91
ILE A  82
 None
 1.02A 1xozA-5ey9A:
undetectable		 1xozA-5ey9A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 11 GLY A 216
GLU A 215
MET A 356
ASP A 220
ARG A 334
 None
 1.39A 2ac7A-5ey9A:
undetectable
2ac7B-5ey9A:
undetectable		 2ac7A-5ey9A:
19.79
2ac7B-5ey9A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 11 ARG A 334
GLY A 216
GLU A 215
MET A 356
ASP A 220
 None
 1.40A 2ac7A-5ey9A:
undetectable
2ac7B-5ey9A:
undetectable		 2ac7A-5ey9A:
19.79
2ac7B-5ey9A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_A_SAMA501_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 12 GLY A 244
VAL A  25
ALA A  37
ALA A 240
TYR A  38
 None
 1.41A 2avdA-5ey9A:
undetectable		 2avdA-5ey9A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 12 GLY A 244
VAL A  25
ALA A  37
ALA A 240
TYR A  38
 None
 1.41A 2avdB-5ey9A:
undetectable		 2avdB-5ey9A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 12 GLU A 346
PHE A 441
ILE A 479
LEU A 477
GLY A 343
 None
None
5SV  A 701 (-4.0A)
None
5SV  A 701 (-3.8A)
 1.31A 2e7fB-5ey9A:
undetectable		 2e7fB-5ey9A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JST_A_HLTA101_1
(FOUR-ALPHA-HELIX
BUNDLE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		4 / 5 ALA A 284
TRP A 225
LEU A 266
ALA A 288
 None
 0.99A 2jstA-5ey9A:
undetectable
2jstB-5ey9A:
undetectable		 2jstA-5ey9A:
8.02
2jstB-5ey9A:
8.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 12 GLU A 346
PHE A 441
ILE A 479
LEU A 477
GLY A 343
 None
None
5SV  A 701 (-4.0A)
None
5SV  A 701 (-3.8A)
 1.36A 2ogyB-5ey9A:
undetectable		 2ogyB-5ey9A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 12 TYR A 342
PRO A 281
ALA A 284
ALA A 345
THR A 186
 5SV  A 701 (-4.8A)
None
None
5SV  A 701 (-4.7A)
None
 1.23A 2x2nA-5ey9A:
undetectable		 2x2nA-5ey9A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_2
(NEURAMINIDASE A)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		4 / 6 ASP A 568
ILE A 566
LEU A 587
GLU A 562
 None
 1.04A 2ya7A-5ey9A:
undetectable		 2ya7A-5ey9A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		4 / 6 ASP A 568
ILE A 566
LEU A 587
GLU A 562
 None
 1.06A 2ya7B-5ey9A:
undetectable		 2ya7B-5ey9A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		4 / 6 ASP A 568
ILE A 566
LEU A 587
GLU A 562
 None
 1.04A 2ya7D-5ey9A:
undetectable		 2ya7D-5ey9A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 12 LEU A  70
THR A 130
VAL A 159
VAL A 156
ILE A  80
 None
 1.13A 3bf1A-5ey9A:
undetectable
3bf1B-5ey9A:
undetectable		 3bf1A-5ey9A:
17.98
3bf1B-5ey9A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_0
(N,N-DIMETHYLTRANSFER
ASE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 12 GLY A 233
LEU A 310
PHE A 249
SER A 224
LEU A 266
 None
5SV  A 701 (-3.9A)
None
None
None
 1.38A 3bxoA-5ey9A:
undetectable		 3bxoA-5ey9A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_2
(DIHYDROFOLATE
REDUCTASE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		4 / 5 ASP A 584
ILE A 570
VAL A 515
THR A 592
 None
 0.98A 3eigA-5ey9A:
undetectable		 3eigA-5ey9A:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_1
(GLYCINE
N-METHYLTRANSFERASE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		3 / 3 LEU A 226
HIS A 230
MET A 232
 None
5SV  A 701 (-3.9A)
5SV  A 701 (-3.6A)
 0.93A 3thrD-5ey9A:
undetectable		 3thrD-5ey9A:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		4 / 5 THR A 348
GLY A 427
ASN A 202
TYR A 182
 None
 1.15A 3u8qA-5ey9A:
undetectable		 3u8qA-5ey9A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_D_CLMD221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 12 LEU A 615
VAL A 588
PHE A 518
ALA A 516
CYH A 606
 None
 1.34A 3u9fD-5ey9A:
undetectable
3u9fE-5ey9A:
undetectable		 3u9fD-5ey9A:
15.10
3u9fE-5ey9A:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_G_CLMG221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 12 LEU A 615
VAL A 588
PHE A 518
ALA A 516
CYH A 606
 None
 1.41A 3u9fG-5ey9A:
undetectable
3u9fH-5ey9A:
undetectable		 3u9fG-5ey9A:
15.10
3u9fH-5ey9A:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRI_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 10 TYR A 472
VAL A 394
SER A 352
TYR A 342
ILE A 419
 None
GOL  A 702 ( 4.8A)
None
5SV  A 701 (-4.8A)
None
 1.35A 3vriA-5ey9A:
undetectable
3vriC-5ey9A:
undetectable		 3vriA-5ey9A:
17.14
3vriC-5ey9A:
1.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 11 LEU A 486
ILE A 402
ILE A 416
LEU A 370
VAL A 386
 None
 1.03A 3w67A-5ey9A:
undetectable		 3w67A-5ey9A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 12 ILE A  92
VAL A 242
PHE A  95
ILE A  82
LEU A 203
 None
 1.13A 3w68C-5ey9A:
undetectable		 3w68C-5ey9A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_A_T3A1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 12 ARG A 221
PHE A 277
GLY A 222
VAL A 223
GLU A 272
 None
 1.06A 4bvaA-5ey9A:
undetectable		 4bvaA-5ey9A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_B_T3B1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 12 ARG A 221
PHE A 277
GLY A 222
VAL A 223
GLU A 272
 None
 1.04A 4bvaB-5ey9A:
2.7		 4bvaB-5ey9A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 12 GLU A 346
PHE A 441
ILE A 479
LEU A 477
GLY A 343
 None
None
5SV  A 701 (-4.0A)
None
5SV  A 701 (-3.8A)
 1.30A 4djfB-5ey9A:
undetectable		 4djfB-5ey9A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		4 / 6 ASN A 311
ALA A 279
THR A 236
LEU A 349
 None
5SV  A 701 ( 3.7A)
5SV  A 701 ( 3.7A)
5SV  A 701 (-4.6A)
 0.96A 4ejgD-5ey9A:
undetectable		 4ejgD-5ey9A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		4 / 8 PHE A 249
LEU A  91
ILE A  92
ILE A  54
 None
 0.83A 4em2A-5ey9A:
undetectable		 4em2A-5ey9A:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		4 / 8 ILE A 601
ARG A 603
PRO A 227
MET A 232
 None
None
None
5SV  A 701 (-3.6A)
 1.13A 4f4dB-5ey9A:
4.0		 4f4dB-5ey9A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MV7_A_PPFA501_1
(BIOTIN CARBOXYLASE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		4 / 7 ASN A 523
VAL A 520
GLU A 546
ARG A 607
 None
 1.06A 4mv7A-5ey9A:
4.0		 4mv7A-5ey9A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 12 ASN A 311
GLY A 343
ILE A 419
GLY A 467
SER A 313
 None
5SV  A 701 (-3.8A)
None
None
5SV  A 701 (-4.6A)
 1.21A 4obwC-5ey9A:
undetectable		 4obwC-5ey9A:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_1
(ANDROGEN RECEPTOR)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 12 LEU A  98
GLY A  96
LEU A 132
VAL A 105
THR A  74
 None
 1.25A 4ojbA-5ey9A:
undetectable		 4ojbA-5ey9A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 12 LEU A  98
GLY A  96
LEU A 132
VAL A 105
THR A  74
 None
 1.22A 4okbA-5ey9A:
undetectable		 4okbA-5ey9A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 12 LEU A  98
GLY A  96
LEU A 132
VAL A 105
THR A  74
 None
 1.23A 4okxA-5ey9A:
undetectable		 4okxA-5ey9A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 12 LEU A  98
GLY A  96
LEU A 132
VAL A 105
THR A  74
 None
 1.08A 4olmA-5ey9A:
undetectable		 4olmA-5ey9A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 12 ALA A 400
GLY A 395
GLN A 209
ALA A 345
GLY A 343
 None
None
None
5SV  A 701 (-4.7A)
5SV  A 701 (-3.8A)
 1.20A 4r29A-5ey9A:
undetectable		 4r29A-5ey9A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CU6_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		4 / 6 TYR A 610
VAL A 551
PRO A 594
ALA A 516
 None
 0.90A 5cu6A-5ey9A:
undetectable		 5cu6A-5ey9A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_A_GBMA801_1
(PROLINE--TRNA LIGASE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 12 TYR A 182
LEU A 203
THR A 348
GLY A 427
ILE A 428
 None
 1.10A 5ifuA-5ey9A:
undetectable		 5ifuA-5ey9A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA609_0
(NADH DEHYDROGENASE,
PUTATIVE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		3 / 3 VAL A 223
SER A 224
TRP A 262
 None
 0.96A 5jwaA-5ey9A:
undetectable		 5jwaA-5ey9A:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OTR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		4 / 5 TYR A 610
VAL A 551
PRO A 594
ALA A 516
 None
 0.88A 5otrA-5ey9A:
undetectable		 5otrA-5ey9A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PHH_A_LDPA414_1
(LYSINE-SPECIFIC
DEMETHYLASE 4D)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		4 / 6 GLU A 265
ARG A 221
ALA A 267
LEU A 266
 None
 1.02A 5phhA-5ey9A:
undetectable		 5phhA-5ey9A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 12 ALA A 104
PHE A  95
LEU A  98
ALA A  97
VAL A 207
 None
 1.04A 5z12C-5ey9A:
undetectable		 5z12C-5ey9A:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		3 / 3 LYS A 600
LEU A 226
ASP A 231
 5SV  A 701 (-2.6A)
None
5SV  A 701 (-2.9A)
 0.88A 5zv2A-5ey9A:
undetectable		 5zv2A-5ey9A:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_B_SAMB505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		5 / 12 TRP A 420
ILE A 483
TYR A 469
ARG A 482
GLY A 481
 None
None
None
5SV  A 701 (-3.9A)
None
 1.47A 6bp4B-5ey9A:
undetectable		 6bp4B-5ey9A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EP4_A_DMEA601_1
(CHOLINESTERASE)		 5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32
(Mycobacterium
marinum) 		4 / 5 TRP A  28
GLU A 218
TYR A  38
HIS A 245
 None
 1.37A 6ep4A-5ey9A:
undetectable		 6ep4A-5ey9A:
9.20