SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5eyg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5eyg INOSITOL
MONOPHOSPHATASE
(Staphylococcus
aureus) 		3 / 3 CYH A 104
PRO A  89
ASP A 209
 None
None
CA  A 301 ( 3.0A)
 1.01A 3hlwB-5eygA:
undetectable		 3hlwB-5eygA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF2_A_4CHA506_0
(NADPH DEHYDROGENASE)		 5eyg INOSITOL
MONOPHOSPHATASE
(Staphylococcus
aureus) 		4 / 6 THR A   5
HIS A  65
HIS A  83
TYR A 109
 PGE  A 306 ( 4.8A)
PGE  A 306 (-4.1A)
PGE  A 306 (-3.7A)
PGE  A 306 (-4.5A)
 1.38A 4df2A-5eygA:
undetectable		 4df2A-5eygA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 5eyg INOSITOL
MONOPHOSPHATASE
(Staphylococcus
aureus) 		4 / 7 PHE A  57
PHE A  54
PHE A  62
LEU A 107
 None
 0.95A 4ejgA-5eygA:
undetectable		 4ejgA-5eygA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 5eyg INOSITOL
MONOPHOSPHATASE
(Staphylococcus
aureus) 		4 / 8 PHE A  57
PHE A  54
PHE A  62
LEU A 107
 None
 0.90A 4ejgB-5eygA:
undetectable		 4ejgB-5eygA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 5eyg INOSITOL
MONOPHOSPHATASE
(Staphylococcus
aureus) 		5 / 11 LEU A  96
TYR A 103
GLY A 186
ILE A  90
ASP A  47
 None
 1.36A 5hjiA-5eygA:
undetectable		 5hjiA-5eygA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 5eyg INOSITOL
MONOPHOSPHATASE
(Staphylococcus
aureus) 		4 / 6 TYR A 121
ASP A 188
LEU A 187
GLY A 186
 None
 0.97A 5nooC-5eygA:
undetectable		 5nooC-5eygA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5eyg INOSITOL
MONOPHOSPHATASE
(Staphylococcus
aureus) 		5 / 12 LEU A 255
PHE A 159
ILE A 241
GLN A 213
ILE A 157
 None
 1.09A 5y2tB-5eygA:
undetectable		 5y2tB-5eygA:
undetectable