SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5eyy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V2X_A_SAMA400_0
(TRNA (GM18)
METHYLTRANSFERASE)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		6 / 12 GLY A 106
GLY A 221
ILE A  89
LEU A  34
VAL A  48
ALA A 218
 MDM  A 304 (-3.4A)
MDM  A 304 (-3.2A)
None
None
None
None
 1.48A 1v2xA-5eyyA:
undetectable		 1v2xA-5eyyA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		5 / 12 SER A  72
ALA A 127
LEU A 109
LEU A 111
THR A 132
 None
 1.04A 2nyuB-5eyyA:
undetectable		 2nyuB-5eyyA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		4 / 7 PRO A  81
THR A  42
PRO A  43
VAL A  44
 None
 1.09A 2v41E-5eyyA:
undetectable
2v41F-5eyyA:
undetectable		 2v41E-5eyyA:
24.03
2v41F-5eyyA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		3 / 3 SER A  27
ARG A  25
GLN A  33
 None
 0.83A 2xnrA-5eyyA:
undetectable		 2xnrA-5eyyA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A9E_B_REAB1_1
(RETINOIC ACID
RECEPTOR ALPHA)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		5 / 11 LEU A 109
ILE A  89
PHE A 130
VAL A 125
LEU A 126
 None
 1.20A 3a9eB-5eyyA:
undetectable		 3a9eB-5eyyA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGG_A_CHDA211_0
(CMER)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		4 / 7 PHE A  74
PHE A 216
PHE A  70
SER A  72
 None
 1.44A 3hggA-5eyyA:
undetectable		 3hggA-5eyyA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_2
(PROTEASE)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		5 / 10 LEU A  52
GLY A  49
ALA A  24
ILE A  89
ILE A  51
 None
 1.07A 3nu6B-5eyyA:
undetectable		 3nu6B-5eyyA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		3 / 3 THR A 170
ASN A 172
GLU A 230
 None
 0.56A 3v4tA-5eyyA:
undetectable
3v4tC-5eyyA:
undetectable		 3v4tA-5eyyA:
18.71
3v4tC-5eyyA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		5 / 12 VAL A 173
SER A  72
PHE A 216
ILE A  51
LEU A  34
 None
 1.12A 3w67D-5eyyA:
undetectable		 3w67D-5eyyA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		4 / 8 SER A   7
LEU A 174
SER A 233
THR A 235
 None
 0.73A 4iklA-5eyyA:
undetectable
4iklB-5eyyA:
undetectable		 4iklA-5eyyA:
23.58
4iklB-5eyyA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		3 / 3 ASP A 131
ASP A 142
ASN A 137
 CA  A 302 ( 2.1A)
MN  A 303 ( 2.7A)
MDM  A 304 (-2.9A)
 0.83A 4q5mA-5eyyA:
undetectable		 4q5mA-5eyyA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWL_A_ASCA303_0
(DIOSCORIN 5)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		5 / 10 ASP A 151
VAL A 186
VAL A 175
PHE A 130
ALA A  90
 None
 1.26A 4twlA-5eyyA:
undetectable		 4twlA-5eyyA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWL_B_ASCB304_0
(DIOSCORIN 5)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		5 / 10 ASP A 151
VAL A 186
VAL A 175
PHE A 130
ALA A  90
 None
 1.29A 4twlB-5eyyA:
undetectable		 4twlB-5eyyA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_ADNA2414_1
(RNA-DIRECTED RNA
POLYMERASE L)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		4 / 6 GLU A 129
PHE A 133
TYR A 134
HIS A 147
 MN  A 303 (-2.6A)
MDM  A 304 ( 3.5A)
None
MN  A 303 (-3.3A)
 1.29A 4uciA-5eyyA:
undetectable		 4uciA-5eyyA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		4 / 7 GLU A 129
PHE A 133
TYR A 134
HIS A 147
 MN  A 303 (-2.6A)
MDM  A 304 ( 3.5A)
None
MN  A 303 (-3.3A)
 1.28A 4uciB-5eyyA:
undetectable		 4uciB-5eyyA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2S_A_ACTA107_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		3 / 3 VAL A 187
THR A 189
ARG A 195
 None
 0.61A 5b2sB-5eyyA:
undetectable		 5b2sB-5eyyA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2T_A_ACTA108_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		3 / 3 VAL A 187
THR A 189
ARG A 195
 None
 0.62A 5b2tB-5eyyA:
undetectable		 5b2tB-5eyyA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		3 / 3 THR A 116
ALA A 122
ASN A 119
 None
NAG  A 301 ( 3.8A)
NAG  A 301 (-1.6A)
 0.62A 5ersA-5eyyA:
undetectable		 5ersA-5eyyA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		3 / 3 VAL A 161
TYR A 196
GLN A 197
 None
 0.67A 5qgkA-5eyyA:
undetectable		 5qgkA-5eyyA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		3 / 3 VAL A 161
TYR A 196
GLN A 197
 None
 0.66A 5qgrA-5eyyA:
undetectable		 5qgrA-5eyyA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		3 / 3 VAL A 161
TYR A 196
GLN A 197
 None
 0.59A 5qgtA-5eyyA:
undetectable		 5qgtA-5eyyA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		4 / 8 THR A 183
TYR A 177
THR A 176
GLN A  71
 None
 1.03A 5tzoA-5eyyA:
undetectable		 5tzoA-5eyyA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		4 / 8 THR A 183
TYR A 177
THR A 176
GLN A  71
 None
 1.05A 5tzoB-5eyyA:
4.9		 5tzoB-5eyyA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		4 / 8 THR A 183
TYR A 177
THR A 176
GLN A  71
 None
 1.02A 5tzoC-5eyyA:
5.0		 5tzoC-5eyyA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		4 / 5 PHE A  76
THR A 189
GLU A 230
ASN A  10
 None
 1.48A 5ybbA-5eyyA:
undetectable		 5ybbA-5eyyA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		4 / 6 GLY A  49
VAL A  18
PHE A  11
PHE A   8
 None
 0.96A 6h7lA-5eyyA:
undetectable		 6h7lA-5eyyA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		4 / 6 VAL A  18
PHE A 216
PHE A  11
PHE A   8
 None
 0.99A 6h7lA-5eyyA:
undetectable		 6h7lA-5eyyA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		4 / 6 GLY A  49
VAL A  18
PHE A  11
PHE A   8
 None
 0.96A 6h7lB-5eyyA:
undetectable		 6h7lB-5eyyA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5eyy CENTROLOBIUM
TOMENTOSUM LECTIN
(Centrolobium
tomentosum) 		4 / 6 VAL A  18
PHE A 216
PHE A  11
PHE A   8
 None
 1.00A 6h7lB-5eyyA:
undetectable		 6h7lB-5eyyA:
16.60