SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ez1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E7C_C_ACTC506_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	5ez1	PUTATIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE HP_0175 (Helicobacter pylori)	4 / 5	ARG A 160 ILE A 252 HIS A 158 GLY A 212	None	1.37A	4e7cC-5ez1A: undetectable	4e7cC-5ez1A: 22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IIZ_A_LURA201_1 (TRANSTHYRETIN)	5ez1	PUTATIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE HP_0175 (Helicobacter pylori)	3 / 3	LYS A 254 LEU A 251 ALA A 157	None	0.62A	4iizA-5ez1A: undetectable	4iizA-5ez1A: 17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HU9_I_PCFI101_0 (CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL CYTOCHROME B-C1 COMPLEX SUBUNIT 9 CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL)	5ez1	PUTATIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE HP_0175 (Helicobacter pylori)	5 / 11	ASP A 178 TYR A 235 GLY A 209 SER A 202 ALA A 205	None	1.37A	6hu9A-5ez1A: undetectable 6hu9E-5ez1A: 1.1 6hu9I-5ez1A: undetectable	6hu9A-5ez1A: 22.25 6hu9E-5ez1A: 23.33 6hu9I-5ez1A: 14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HU9_T_PCFT101_0 (CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL CYTOCHROME B-C1 COMPLEX SUBUNIT 9 CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL)	5ez1	PUTATIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE HP_0175 (Helicobacter pylori)	5 / 10	ASP A 178 TYR A 235 GLY A 209 SER A 202 ALA A 205	None	1.46A	6hu9L-5ez1A: undetectable 6hu9P-5ez1A: undetectable 6hu9T-5ez1A: undetectable	6hu9L-5ez1A: 22.25 6hu9P-5ez1A: 23.33 6hu9T-5ez1A: 14.02

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4E7C_C_ACTC506_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","5ez1","PUTATIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE HP_0175","Helicobacter pylori",4,"ARG A 160;ILE A 252;HIS A 158;GLY A 212","None","1.37A","4e7cC-5ez1A:undetectable","4e7cC-5ez1A:22.07"],["4IIZ_A_LURA201_1","TRANSTHYRETIN","5ez1","PUTATIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE HP_0175","Helicobacter pylori",3,"LYS A 254;LEU A 251;ALA A 157","None","0.62A","4iizA-5ez1A:undetectable","4iizA-5ez1A:17.39"],["6HU9_I_PCFI101_0","CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL;CYTOCHROME B-C1 COMPLEX SUBUNIT 9;CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL","5ez1","PUTATIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE HP_0175","Helicobacter pylori",5,"ASP A 178;TYR A 235;GLY A 209;SER A 202;ALA A 205","None","1.37A","6hu9A-5ez1A:undetectable;6hu9E-5ez1A:1.1;6hu9I-5ez1A:undetectable","6hu9A-5ez1A:22.25;6hu9E-5ez1A:23.33;6hu9I-5ez1A:14.02"],["6HU9_T_PCFT101_0","CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL;CYTOCHROME B-C1 COMPLEX SUBUNIT 9;CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL","5ez1","PUTATIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE HP_0175","Helicobacter pylori",5,"ASP A 178;TYR A 235;GLY A 209;SER A 202;ALA A 205","None","1.46A","6hu9L-5ez1A:undetectable;6hu9P-5ez1A:undetectable;6hu9T-5ez1A:undetectable","6hu9L-5ez1A:22.25;6hu9P-5ez1A:23.33;6hu9T-5ez1A:14.02"]]