SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ezj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 5ezj FAB C12 HEAVY CHAIN
(Homo
sapiens) 		4 / 5 SER A 132
ALA A 134
PHE A 166
LEU A 190
 None
 0.41A 5mthA-5ezjA:
19.1		 5mthA-5ezjA:
66.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_D_ACTD404_0
(L-LYSINE
3-HYDROXYLASE)		 5ezj FAB C12 HEAVY CHAIN
(Homo
sapiens) 		4 / 6 GLN A  59
GLU A  60
ALA A  54
GLN A  53
 None
 1.42A 6f6jC-5ezjA:
undetectable
6f6jD-5ezjA:
undetectable		 6f6jC-5ezjA:
19.61
6f6jD-5ezjA:
19.61