SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ezv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 5ezv 5'-AMP-ACTIVATED
PROTEIN KINASE
SUBUNIT BETA-1
(Homo
sapiens) 		5 / 12 ILE B 214
LEU B 210
LEU B 228
LEU B 265
THR B 264
 None
 1.21A 6b52A-5ezvB:
undetectable		 6b52A-5ezvB:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 5ezv 5'-AMP-ACTIVATED
PROTEIN KINASE
SUBUNIT BETA-1
(Homo
sapiens) 		5 / 12 PRO B 140
ILE B 141
ILE B 152
VAL B 149
PHE B 127
 None
 1.12A 6hlpA-5ezvB:
undetectable		 6hlpA-5ezvB:
18.18