SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f05'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_I_SAMI199_0
(METHIONINE REPRESSOR)		 5f05 PHI CLASS
GLUTATHIONE
TRANSFERASE GSTF5
(Populus
trichocarpa) 		5 / 11 GLU A  67
PRO A  51
HIS A   7
ALA A  57
GLY A   8
 GSH  A 301 (-2.6A)
None
None
None
None
 1.03A 1mjqI-5f05A:
undetectable
1mjqJ-5f05A:
undetectable		 1mjqI-5f05A:
14.95
1mjqJ-5f05A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_0
(MODIFICATION
METHYLASE RSRI)		 5f05 PHI CLASS
GLUTATHIONE
TRANSFERASE GSTF5
(Populus
trichocarpa) 		5 / 12 ASP A  60
GLY A   8
SER A   9
ALA A  58
ALA A  57
 None
 1.26A 1nw5A-5f05A:
undetectable		 1nw5A-5f05A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 5f05 PHI CLASS
GLUTATHIONE
TRANSFERASE GSTF5
(Populus
trichocarpa) 		4 / 8 ASP A 160
LEU A 151
THR A 163
TYR A 156
 None
 1.09A 1rmtD-5f05A:
undetectable		 1rmtD-5f05A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QT0_A_486A4_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5f05 PHI CLASS
GLUTATHIONE
TRANSFERASE GSTF5
(Populus
trichocarpa) 		4 / 4 LYS A  82
GLN A  78
ILE A  71
LEU A  19
 None
 1.44A 3qt0A-5f05A:
undetectable		 3qt0A-5f05A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 5f05 PHI CLASS
GLUTATHIONE
TRANSFERASE GSTF5
(Populus
trichocarpa) 		4 / 6 ARG A  17
PRO A  56
GLU A  67
SER A  68
 GSH  A 301 ( 4.9A)
GSH  A 301 ( 4.6A)
GSH  A 301 (-2.6A)
GSH  A 301 (-2.5A)
 0.96A 3vlnA-5f05A:
20.7		 3vlnA-5f05A:
26.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5f05 PHI CLASS
GLUTATHIONE
TRANSFERASE GSTF5
(Populus
trichocarpa) 		3 / 3 HIS A  46
GLU A  40
ASN A  33
 None
 0.94A 4bupB-5f05A:
undetectable		 4bupB-5f05A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 5f05 PHI CLASS
GLUTATHIONE
TRANSFERASE GSTF5
(Populus
trichocarpa) 		4 / 7 ILE A  71
HIS A   7
ALA A  58
VAL A  59
 None
 0.79A 4g77A-5f05A:
undetectable		 4g77A-5f05A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 5f05 PHI CLASS
GLUTATHIONE
TRANSFERASE GSTF5
(Populus
trichocarpa) 		4 / 8 HIS A 169
GLU A 103
SER A 112
PRO A 109
 None
 1.19A 4uhxA-5f05A:
undetectable		 4uhxA-5f05A:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 5f05 PHI CLASS
GLUTATHIONE
TRANSFERASE GSTF5
(Populus
trichocarpa) 		4 / 8 HIS A 169
GLU A 103
SER A 112
PRO A 109
 None
 1.19A 4uhxA-5f05A:
undetectable		 4uhxA-5f05A:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5f05 PHI CLASS
GLUTATHIONE
TRANSFERASE GSTF5
(Populus
trichocarpa) 		4 / 6 PRO A  56
HIS A 168
ALA A 203
TYR A  79
 GSH  A 301 ( 4.6A)
None
None
None
 1.00A 5igiA-5f05A:
undetectable		 5igiA-5f05A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 5f05 PHI CLASS
GLUTATHIONE
TRANSFERASE GSTF5
(Populus
trichocarpa) 		3 / 3 HIS A  46
GLU A  40
ASN A  33
 None
 0.99A 5wbvA-5f05A:
undetectable		 5wbvA-5f05A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 5f05 PHI CLASS
GLUTATHIONE
TRANSFERASE GSTF5
(Populus
trichocarpa) 		3 / 3 HIS A  46
GLU A  40
ASN A  33
 None
 1.00A 5wbvB-5f05A:
undetectable		 5wbvB-5f05A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 5f05 PHI CLASS
GLUTATHIONE
TRANSFERASE GSTF5
(Populus
trichocarpa) 		5 / 12 VAL A 146
TRP A 194
ASP A 166
SER A  72
VAL A 102
 None
 1.24A 6h7lA-5f05A:
undetectable		 6h7lA-5f05A:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 5f05 PHI CLASS
GLUTATHIONE
TRANSFERASE GSTF5
(Populus
trichocarpa) 		5 / 12 VAL A 146
TRP A 194
ASP A 166
SER A  72
VAL A 102
 None
 1.25A 6h7lB-5f05A:
undetectable		 6h7lB-5f05A:
15.57