SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f06'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 5f06 GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		5 / 12 ARG A  68
GLU A 104
TYR A 176
VAL A 116
ASN A 109
 GSH  A 301 (-4.0A)
None
None
None
None
 1.36A 3bjmA-5f06A:
undetectable		 3bjmA-5f06A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 5f06 GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		5 / 12 ARG A  68
GLU A 104
TYR A 176
VAL A 116
ASN A 109
 GSH  A 301 (-4.0A)
None
None
None
None
 1.43A 3g0bA-5f06A:
undetectable		 3g0bA-5f06A:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 5f06 GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		5 / 12 ARG A  68
GLU A 104
TYR A 176
VAL A 116
ASN A 109
 GSH  A 301 (-4.0A)
None
None
None
None
 1.42A 3g0bB-5f06A:
undetectable		 3g0bB-5f06A:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 5f06 GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		5 / 12 ARG A  68
GLU A 104
TYR A 176
VAL A 116
ASN A 109
 GSH  A 301 (-4.0A)
None
None
None
None
 1.45A 3g0bC-5f06A:
undetectable		 3g0bC-5f06A:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 5f06 GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		5 / 12 ARG A  68
GLU A 104
TYR A 176
VAL A 116
ASN A 109
 GSH  A 301 (-4.0A)
None
None
None
None
 1.42A 3g0bD-5f06A:
undetectable		 3g0bD-5f06A:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 5f06 GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		4 / 6 ARG A  16
PRO A  55
GLU A  66
SER A  67
 GSH  A 301 ( 4.9A)
GSH  A 301 ( 4.8A)
GSH  A 301 (-2.8A)
GSH  A 301 (-2.7A)
 0.98A 3vlnA-5f06A:
20.0		 3vlnA-5f06A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 5f06 GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		5 / 12 ARG A  68
GLU A 104
TYR A 176
VAL A 116
ASN A 109
 GSH  A 301 (-4.0A)
None
None
None
None
 1.45A 3w2tA-5f06A:
undetectable		 3w2tA-5f06A:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 5f06 GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		5 / 12 ARG A  68
GLU A 104
TYR A 176
VAL A 116
ASN A 109
 GSH  A 301 (-4.0A)
None
None
None
None
 1.42A 3w2tB-5f06A:
undetectable		 3w2tB-5f06A:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_D_ACHD301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5f06 GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		4 / 8 TYR A 148
THR A 101
TYR A 108
TRP A 195
 None
 1.35A 3wipD-5f06A:
undetectable
3wipE-5f06A:
undetectable		 3wipD-5f06A:
19.09
3wipE-5f06A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 5f06 GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		3 / 3 TYR A  83
ARG A  87
SER A 164
 None
 1.17A 4dr2I-5f06A:
undetectable
4dr2J-5f06A:
undetectable		 4dr2I-5f06A:
24.09
4dr2J-5f06A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 5f06 GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		3 / 3 ASP A 167
TYR A 163
TRP A 195
 None
 1.33A 4p7nA-5f06A:
undetectable		 4p7nA-5f06A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 5f06 GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		4 / 5 ILE A  54
PRO A  55
HIS A 169
VAL A 208
 GSH  A 301 (-4.2A)
GSH  A 301 ( 4.8A)
None
None
 1.33A 4s0vA-5f06A:
undetectable		 4s0vA-5f06A:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 5f06 GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		4 / 4 ASN A 213
SER A 200
ALA A 209
VAL A 208
 None
 1.10A 5nm5A-5f06A:
undetectable		 5nm5A-5f06A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5f06 GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		5 / 11 LEU A 158
GLY A 160
GLU A  93
VAL A  99
ALA A 166
 None
 1.01A 5o96G-5f06A:
undetectable		 5o96G-5f06A:
21.18