SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f07'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 5f07 PUTATIVE GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		4 / 6 LEU A  35
VAL A  54
VAL A  12
GLN A  15
 GSH  A 301 ( 4.1A)
GSH  A 301 (-3.8A)
GSH  A 301 (-4.3A)
None
 0.93A 1e7aB-5f07A:
undetectable		 1e7aB-5f07A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_H_FUAH709_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5f07 PUTATIVE GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		5 / 12 SER A  37
VAL A  54
VAL A  12
ALA A  11
HIS A  32
 None
GSH  A 301 (-3.8A)
GSH  A 301 (-4.3A)
GSH  A 301 ( 4.4A)
None
 1.24A 1q23H-5f07A:
undetectable
1q23I-5f07A:
undetectable		 1q23H-5f07A:
20.55
1q23I-5f07A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 5f07 PUTATIVE GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		4 / 6 ARG A  16
PRO A  55
GLU A  66
SER A  67
 None
GSH  A 301 ( 4.6A)
GSH  A 301 (-2.7A)
GSH  A 301 (-2.7A)
 0.92A 3vlnA-5f07A:
21.3		 3vlnA-5f07A:
25.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 5f07 PUTATIVE GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		5 / 12 LEU A 167
CYH A  20
ALA A  76
GLY A  87
LEU A  86
 None
 1.27A 4j7xB-5f07A:
undetectable		 4j7xB-5f07A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 5f07 PUTATIVE GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		4 / 4 VAL A 133
THR A 135
GLU A 137
GLU A 138
 None
 1.39A 4l78A-5f07A:
undetectable		 4l78A-5f07A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_1
(REGULATORY PROTEIN
TETR)		 5f07 PUTATIVE GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Populus
trichocarpa) 		4 / 7 GLY A 125
ILE A 120
GLN A  40
ASP A  36
 None
None
GSH  A 301 (-3.8A)
None
 1.13A 5vlmC-5f07A:
undetectable		 5vlmC-5f07A:
19.91