SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f0p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN3_A_ID8A1356_1
(THYROXINE-BINDING
GLOBULIN)		 5f0p SORTING NEXIN-3
(Homo
sapiens) 		4 / 8 LEU C 145
LYS C 128
ASN C 127
LEU C  29
 None
 0.96A 2xn3A-5f0pC:
undetectable
2xn3B-5f0pC:
undetectable		 2xn3A-5f0pC:
19.93
2xn3B-5f0pC:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5f0p SORTING NEXIN-3
(Homo
sapiens) 		4 / 6 PHE C 144
LEU C 122
VAL C  33
ASP C  73
 None
 1.11A 4ek1A-5f0pC:
undetectable		 4ek1A-5f0pC:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5f0p SORTING NEXIN-3
(Homo
sapiens) 		4 / 8 GLN C 100
ILE C 109
GLY C  94
GLU C  75
 SO4  C 202 (-3.3A)
SO4  C 202 (-4.4A)
None
None
 1.02A 4fgjA-5f0pC:
undetectable
4fgjB-5f0pC:
undetectable		 4fgjA-5f0pC:
20.25
4fgjB-5f0pC:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5f0p SORTING NEXIN-3
(Homo
sapiens) 		3 / 3 GLN C  37
THR C  38
THR C  47
 None
 0.83A 4fu9A-5f0pC:
undetectable		 4fu9A-5f0pC:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5f0p SORTING NEXIN-3
(Homo
sapiens) 		3 / 3 GLN C  37
THR C  38
THR C  47
 None
 0.81A 4fufA-5f0pC:
undetectable		 4fufA-5f0pC:
20.08