SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f15'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 6 LEU A 551
TRP A 529
PHE A 525
VAL A 522
 None
 1.02A 1ibgH-5f15A:
undetectable		 1ibgH-5f15A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 6 LEU A 361
LEU A 303
TRP A 296
PHE A 293
 None
 1.19A 1ru9H-5f15A:
undetectable
1ru9L-5f15A:
undetectable		 1ru9H-5f15A:
17.47
1ru9L-5f15A:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 6 LEU A 361
LEU A 303
TRP A 296
PHE A 293
 None
 1.16A 1rukH-5f15A:
undetectable
1rukL-5f15A:
undetectable		 1rukH-5f15A:
17.47
1rukL-5f15A:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_2
(PROTEASE RETROPEPSIN)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 11 ALA A 145
GLY A 291
ILE A 290
VAL A 349
ILE A 350
 None
MPG  A 625 ( 3.7A)
MPG  A 625 ( 4.6A)
None
None
 0.90A 1t3rB-5f15A:
undetectable		 1t3rB-5f15A:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 6 GLU A  61
TYR A  77
ASP A 487
ARG A 562
 None
 1.25A 2a3bB-5f15A:
undetectable		 2a3bB-5f15A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 11 ALA A 145
GLY A 291
ILE A 290
VAL A 349
ILE A 350
 None
MPG  A 625 ( 3.7A)
MPG  A 625 ( 4.6A)
None
None
 0.89A 2fxeB-5f15A:
undetectable		 2fxeB-5f15A:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_2
(PROTEASE)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 12 ALA A 145
GLY A 291
ILE A 290
VAL A 349
ILE A 350
 None
MPG  A 625 ( 3.7A)
MPG  A 625 ( 4.6A)
None
None
 0.90A 2o4sB-5f15A:
undetectable		 2o4sB-5f15A:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 8 PHE A 332
ILE A 346
GLY A 291
GLY A 292
 MPG  A 614 (-4.0A)
None
MPG  A 625 ( 3.7A)
MPG  A 603 ( 4.3A)
 0.85A 2qx4A-5f15A:
undetectable
2qx4B-5f15A:
undetectable		 2qx4A-5f15A:
17.19
2qx4B-5f15A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 6 PHE A 332
ILE A 346
GLY A 291
GLY A 292
 MPG  A 614 (-4.0A)
None
MPG  A 625 ( 3.7A)
MPG  A 603 ( 4.3A)
 0.83A 2qx6A-5f15A:
undetectable
2qx6B-5f15A:
undetectable		 2qx6A-5f15A:
17.19
2qx6B-5f15A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 12 LEU A 117
GLY A 163
PHE A  43
LEU A  46
VAL A 347
 MPG  A 611 (-4.3A)
None
MPG  A 610 (-4.3A)
None
None
 1.43A 2w8yA-5f15A:
undetectable		 2w8yA-5f15A:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 10 TYR A 218
ILE A 326
PHE A 318
LEU A 169
LEU A 173
 None
MPG  A 612 ( 4.7A)
None
5TR  A 681 ( 4.3A)
None
 1.40A 2w98A-5f15A:
undetectable		 2w98A-5f15A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 8 TYR A  77
LEU A  80
ALA A 504
HIS A 488
 None
 0.89A 2wekA-5f15A:
2.4		 2wekA-5f15A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 8 TYR A 218
ALA A 328
ALA A 352
LEU A 173
 None
MPG  A 614 ( 3.9A)
None
None
 0.93A 2wx2B-5f15A:
undetectable		 2wx2B-5f15A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1437_1
(ORF12)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 11 SER A 166
SER A 122
GLY A 163
ALA A 162
MET A 159
 None
 1.39A 2xh9A-5f15A:
undetectable		 2xh9A-5f15A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_2
(PROTEASE)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 9 ALA A 145
GLY A 291
ILE A 290
VAL A 349
ILE A 350
 None
MPG  A 625 ( 3.7A)
MPG  A 625 ( 4.6A)
None
None
 0.90A 3ekvB-5f15A:
undetectable		 3ekvB-5f15A:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 8 HIS A 454
ALA A 395
ILE A 398
ASN A 396
 CL  A 680 (-3.9A)
MPG  A 675 ( 4.0A)
None
None
 0.96A 3fxrA-5f15A:
undetectable		 3fxrA-5f15A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_2
(HIV-1 PROTEASE)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 11 ALA A 145
GLY A 291
ILE A 290
VAL A 349
ILE A 350
 None
MPG  A 625 ( 3.7A)
MPG  A 625 ( 4.6A)
None
None
 1.00A 3lzvB-5f15A:
undetectable		 3lzvB-5f15A:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_2
(PROTEASE)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 9 ALA A 145
GLY A 291
ILE A 290
VAL A 349
ILE A 350
 None
MPG  A 625 ( 3.7A)
MPG  A 625 ( 4.6A)
None
None
 1.00A 3ndwB-5f15A:
undetectable		 3ndwB-5f15A:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_1
(PROTEASE)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 12 ALA A 145
GLY A 291
ILE A 290
VAL A 349
ILE A 350
 None
MPG  A 625 ( 3.7A)
MPG  A 625 ( 4.6A)
None
None
 0.98A 3ndxA-5f15A:
undetectable		 3ndxA-5f15A:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_1
(PROTEASE)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 10 ALA A 145
GLY A 291
ILE A 290
VAL A 349
ILE A 350
 None
MPG  A 625 ( 3.7A)
MPG  A 625 ( 4.6A)
None
None
 0.99A 3nujA-5f15A:
undetectable		 3nujA-5f15A:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 8 LEU A 551
VAL A 483
VAL A 565
TYR A 481
 None
 0.94A 3v81C-5f15A:
undetectable		 3v81C-5f15A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 6 ILE A 119
LEU A 142
MET A 159
THR A 160
 MPG  A 602 ( 4.5A)
None
None
None
 1.11A 3wg7A-5f15A:
5.4
3wg7J-5f15A:
undetectable		 3wg7A-5f15A:
23.90
3wg7J-5f15A:
6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 12 PHE A 293
PRO A 295
LEU A 364
VAL A 432
ALA A 440
 None
 1.44A 4a84A-5f15A:
undetectable		 4a84A-5f15A:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_1
(ASPARTYL PROTEASE)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 10 ALA A 145
GLY A 291
ILE A 290
VAL A 349
ILE A 350
 None
MPG  A 625 ( 3.7A)
MPG  A 625 ( 4.6A)
None
None
 0.88A 4dqcA-5f15A:
undetectable		 4dqcA-5f15A:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_1
(ASPARTYL PROTEASE)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 11 ALA A 145
GLY A 291
ILE A 290
VAL A 349
ILE A 350
 None
MPG  A 625 ( 3.7A)
MPG  A 625 ( 4.6A)
None
None
 0.91A 4dqeA-5f15A:
undetectable		 4dqeA-5f15A:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_1
(WILD-TYPE HIV-1
PROTEASE DIMER)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 11 ALA A 145
GLY A 291
ILE A 290
VAL A 349
ILE A 350
 None
MPG  A 625 ( 3.7A)
MPG  A 625 ( 4.6A)
None
None
 0.94A 4dqhA-5f15A:
undetectable		 4dqhA-5f15A:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_0
(METHYLTRANSFERASE
NSUN4)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 12 PRO A 146
GLY A 292
GLY A 291
GLY A 358
LEU A 361
 None
MPG  A 603 ( 4.3A)
MPG  A 625 ( 3.7A)
None
None
 0.87A 4fp9A-5f15A:
undetectable		 4fp9A-5f15A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_0
(METHYLTRANSFERASE
NSUN4)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 12 PRO A 146
GLY A 292
GLY A 291
GLY A 358
LEU A 361
 None
MPG  A 603 ( 4.3A)
MPG  A 625 ( 3.7A)
None
None
 0.87A 4fp9C-5f15A:
undetectable		 4fp9C-5f15A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_0
(METHYLTRANSFERASE
NSUN4)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 12 PRO A 146
GLY A 292
GLY A 291
GLY A 358
LEU A 361
 None
MPG  A 603 ( 4.3A)
MPG  A 625 ( 3.7A)
None
None
 0.87A 4fp9D-5f15A:
undetectable		 4fp9D-5f15A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_0
(METHYLTRANSFERASE
NSUN4)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 12 PRO A 146
GLY A 292
GLY A 291
GLY A 358
LEU A 361
 None
MPG  A 603 ( 4.3A)
MPG  A 625 ( 3.7A)
None
None
 0.87A 4fp9F-5f15A:
undetectable		 4fp9F-5f15A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_0
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 12 PRO A 146
GLY A 292
GLY A 291
GLY A 358
LEU A 361
 None
MPG  A 603 ( 4.3A)
MPG  A 625 ( 3.7A)
None
None
 0.90A 4fzvA-5f15A:
undetectable		 4fzvA-5f15A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 12 ALA A 145
GLY A 291
ILE A 290
VAL A 349
ILE A 350
 None
MPG  A 625 ( 3.7A)
MPG  A 625 ( 4.6A)
None
None
 0.97A 4hlaA-5f15A:
undetectable		 4hlaA-5f15A:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 11 ALA A 145
GLY A 291
ILE A 290
VAL A 349
ILE A 350
 None
MPG  A 625 ( 3.7A)
MPG  A 625 ( 4.6A)
None
None
 0.94A 4hlaB-5f15A:
undetectable		 4hlaB-5f15A:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 8 ARG A  58
TYR A  82
ASP A 158
ARG A 270
 None
None
None
5TR  A 681 (-3.5A)
 1.32A 4kr4C-5f15A:
undetectable		 4kr4C-5f15A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_2
(ASPARTYL PROTEASE)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 10 ALA A 145
GLY A 291
ILE A 290
VAL A 349
ILE A 350
 None
MPG  A 625 ( 3.7A)
MPG  A 625 ( 4.6A)
None
None
 0.90A 4q1wB-5f15A:
undetectable		 4q1wB-5f15A:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_1
(RETINOL-BINDING
PROTEIN 2)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		3 / 3 LYS A 302
TRP A 369
GLN A 372
 CL  A 679 (-2.8A)
None
MPG  A 605 (-3.9A)
 1.49A 4qzuC-5f15A:
0.0		 4qzuC-5f15A:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 7 ALA A 306
SER A 122
GLY A 354
ALA A 357
 None
 0.90A 4r1zB-5f15A:
undetectable		 4r1zB-5f15A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 7 LYS A 203
ARG A 270
ASP A 158
TYR A 345
 5TR  A 681 (-4.0A)
5TR  A 681 (-3.5A)
None
5TR  A 681 (-4.5A)
 1.45A 5a06A-5f15A:
undetectable		 5a06A-5f15A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 7 LYS A 203
ARG A 270
ASP A 158
TYR A 345
 5TR  A 681 (-4.0A)
5TR  A 681 (-3.5A)
None
5TR  A 681 (-4.5A)
 1.47A 5a06C-5f15A:
2.4		 5a06C-5f15A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 7 LYS A 203
ARG A 270
ASP A 158
TYR A 345
 5TR  A 681 (-4.0A)
5TR  A 681 (-3.5A)
None
5TR  A 681 (-4.5A)
 1.47A 5a06D-5f15A:
2.3		 5a06D-5f15A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 7 LYS A 203
ARG A 270
ASP A 158
TYR A 345
 5TR  A 681 (-4.0A)
5TR  A 681 (-3.5A)
None
5TR  A 681 (-4.5A)
 1.47A 5a06E-5f15A:
2.3		 5a06E-5f15A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 7 LYS A 203
ARG A 270
ASP A 158
TYR A 345
 5TR  A 681 (-4.0A)
5TR  A 681 (-3.5A)
None
5TR  A 681 (-4.5A)
 1.46A 5a06F-5f15A:
2.4		 5a06F-5f15A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 12 GLY A 298
PHE A 137
THR A 138
TYR A 439
VAL A 432
 MPG  A 605 (-3.9A)
None
None
None
None
 1.11A 5d0yA-5f15A:
2.8		 5d0yA-5f15A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 6 PHE A 171
SER A 122
ALA A 125
LEU A 169
 MPG  A 617 ( 4.5A)
None
None
5TR  A 681 ( 4.3A)
 1.19A 5dzkB-5f15A:
undetectable
5dzkP-5f15A:
undetectable		 5dzkB-5f15A:
16.67
5dzkP-5f15A:
1.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 7 PHE A 171
SER A 122
ALA A 125
LEU A 169
 MPG  A 617 ( 4.5A)
None
None
5TR  A 681 ( 4.3A)
 1.15A 5dzkD-5f15A:
undetectable
5dzkR-5f15A:
undetectable		 5dzkD-5f15A:
16.67
5dzkR-5f15A:
1.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 8 PHE A 171
SER A 122
ALA A 125
LEU A 169
 MPG  A 617 ( 4.5A)
None
None
5TR  A 681 ( 4.3A)
 1.06A 5dzkF-5f15A:
undetectable
5dzkT-5f15A:
undetectable		 5dzkF-5f15A:
16.67
5dzkT-5f15A:
1.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 6 PHE A 171
SER A 122
ALA A 125
LEU A 169
 MPG  A 617 ( 4.5A)
None
None
5TR  A 681 ( 4.3A)
 1.06A 5dzkg-5f15A:
undetectable
5dzku-5f15A:
undetectable		 5dzkg-5f15A:
16.67
5dzku-5f15A:
1.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 12 PHE A  34
LEU A 433
ALA A 437
PHE A 137
LEU A  39
 MPG  A 602 (-4.6A)
None
MPG  A 602 ( 3.7A)
None
None
 1.22A 5ljbA-5f15A:
undetectable		 5ljbA-5f15A:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 12 PHE A  34
LEU A 433
ALA A 437
PHE A 137
LEU A  39
 MPG  A 602 (-4.6A)
None
MPG  A 602 ( 3.7A)
None
None
 1.20A 5ljcA-5f15A:
undetectable		 5ljcA-5f15A:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB306_0
(WELO5)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		3 / 3 GLU A 506
ARG A  58
TYR A  82
 None
 0.65A 5trqB-5f15A:
undetectable		 5trqB-5f15A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_A_SAMA501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		5 / 12 ALA A 145
PRO A 146
GLY A 291
GLY A 358
LEU A 361
 None
None
MPG  A 625 ( 3.7A)
None
None
 1.09A 5wwsA-5f15A:
undetectable		 5wwsA-5f15A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 5 VAL A 214
GLY A 163
TRP A 148
VAL A 349
 None
 1.06A 6ak3B-5f15A:
2.5		 6ak3B-5f15A:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 6 MET A 159
THR A 160
LEU A 161
LEU A 201
 None
 1.18A 6mvxA-5f15A:
undetectable
6mvxB-5f15A:
3.0
6mvxC-5f15A:
2.9		 6mvxA-5f15A:
18.29
6mvxB-5f15A:
18.29
6mvxC-5f15A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		3 / 3 ILE A  75
THR A  74
PRO A  87
 None
 0.59A 6ncsA-5f15A:
undetectable		 6ncsA-5f15A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 6 ILE A 119
LEU A 142
MET A 159
THR A 160
 MPG  A 602 ( 4.5A)
None
None
None
 1.00A 6nmfN-5f15A:
2.5
6nmfW-5f15A:
undetectable		 6nmfN-5f15A:
23.90
6nmfW-5f15A:
6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6PAH_A_DAHA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 5f15 4-AMINO-4-DEOXY-L-AR
ABINOSE (L-ARA4N)
TRANSFERASE
(Cupriavidus
metallidurans) 		4 / 6 LEU A 157
HIS A 488
TYR A  77
GLU A 506
 None
 1.10A 6pahA-5f15A:
undetectable		 6pahA-5f15A:
19.38