SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f17'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		 5f17 NON-STRUCTURAL
PROTEIN 11
(Equine
arteritis
virus) 		5 / 12 LEU A 159
ALA A 158
PHE A 105
LEU A 148
PRO A 149
 None
 1.11A 1og5A-5f17A:
undetectable		 1og5A-5f17A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 5f17 NON-STRUCTURAL
PROTEIN 11
(Equine
arteritis
virus) 		5 / 12 LEU A 159
ALA A 158
PHE A 105
LEU A 148
PRO A 149
 None
 1.13A 1og5B-5f17A:
undetectable		 1og5B-5f17A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5f17 NON-STRUCTURAL
PROTEIN 11
(Equine
arteritis
virus) 		4 / 7 VAL A  74
SER A 102
ARG A 104
PHE A 105
 None
 0.82A 2f78A-5f17A:
undetectable		 2f78A-5f17A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5f17 NON-STRUCTURAL
PROTEIN 11
(Equine
arteritis
virus) 		4 / 7 VAL A  74
SER A 102
ARG A 104
PHE A 105
 None
 0.72A 2f78B-5f17A:
undetectable		 2f78B-5f17A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5f17 NON-STRUCTURAL
PROTEIN 11
(Equine
arteritis
virus) 		4 / 6 VAL A  74
SER A 102
ARG A 104
PHE A 105
 None
 0.75A 2f8dA-5f17A:
undetectable		 2f8dA-5f17A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 5f17 NON-STRUCTURAL
PROTEIN 11
(Equine
arteritis
virus) 		3 / 3 TYR A  66
GLY A 103
PHE A  73
 None
 0.65A 2m2pB-5f17A:
undetectable		 2m2pB-5f17A:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)		 5f17 NON-STRUCTURAL
PROTEIN 11
(Equine
arteritis
virus) 		4 / 8 ARG A 110
SER A 140
LEU A 151
PRO A 150
 None
 1.09A 3jq7B-5f17A:
undetectable		 3jq7B-5f17A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ201_1
(PROTEIN S100-A4)		 5f17 NON-STRUCTURAL
PROTEIN 11
(Equine
arteritis
virus) 		4 / 8 PHE A 142
GLY A  65
CYH A 205
PHE A 215
 None
 1.07A 3ko0B-5f17A:
undetectable
3ko0J-5f17A:
undetectable		 3ko0B-5f17A:
18.78
3ko0J-5f17A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ201_1
(PROTEIN S100-A4)		 5f17 NON-STRUCTURAL
PROTEIN 11
(Equine
arteritis
virus) 		4 / 8 PHE A 142
GLY A 103
CYH A 205
PHE A 215
 None
 1.06A 3ko0B-5f17A:
undetectable
3ko0J-5f17A:
undetectable		 3ko0B-5f17A:
18.78
3ko0J-5f17A:
18.78