SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f1c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BPX_B_MK1B902_2
(HIV-1 PROTEASE)		 5f1c PUTATIVE
UNCHARACTERIZED
PROTEIN
(Amblyomma
maculatum) 		6 / 12 GLY A 260
ALA A 259
VAL A 275
GLY A 253
VAL A 272
ILE A 273
 None
 1.41A 2bpxB-5f1cA:
undetectable		 2bpxB-5f1cA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD201_1
(PROTEIN S100-A4)		 5f1c PUTATIVE
UNCHARACTERIZED
PROTEIN
(Amblyomma
maculatum) 		4 / 8 GLY A 270
PHE A 250
PHE A 333
PHE A 110
 None
 0.98A 3ko0D-5f1cA:
undetectable
3ko0E-5f1cA:
undetectable		 3ko0D-5f1cA:
12.78
3ko0E-5f1cA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ201_1
(PROTEIN S100-A4)		 5f1c PUTATIVE
UNCHARACTERIZED
PROTEIN
(Amblyomma
maculatum) 		4 / 8 PHE A 333
PHE A 110
GLY A 270
PHE A 250
 None
 0.95A 3ko0B-5f1cA:
undetectable
3ko0J-5f1cA:
undetectable		 3ko0B-5f1cA:
12.78
3ko0J-5f1cA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM201_1
(PROTEIN S100-A4)		 5f1c PUTATIVE
UNCHARACTERIZED
PROTEIN
(Amblyomma
maculatum) 		4 / 7 GLY A 270
PHE A 250
PHE A 333
PHE A 110
 None
 0.88A 3ko0M-5f1cA:
undetectable
3ko0P-5f1cA:
undetectable		 3ko0M-5f1cA:
12.78
3ko0P-5f1cA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS201_1
(PROTEIN S100-A4)		 5f1c PUTATIVE
UNCHARACTERIZED
PROTEIN
(Amblyomma
maculatum) 		4 / 7 PHE A 333
PHE A 110
GLY A 270
PHE A 250
 None
 0.96A 3ko0K-5f1cA:
undetectable
3ko0S-5f1cA:
undetectable		 3ko0K-5f1cA:
12.78
3ko0S-5f1cA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZW_A_SAMA1451_0
(WBDD)		 5f1c PUTATIVE
UNCHARACTERIZED
PROTEIN
(Amblyomma
maculatum) 		5 / 12 ALA A 268
ARG A 313
ILE A 117
GLU A 186
LEU A 192
 None
ATP  A 409 (-2.9A)
None
None
None
 1.14A 4azwA-5f1cA:
undetectable		 4azwA-5f1cA:
20.93