SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f1m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 5f1m PHOSPHORYLATED
PROTEIN PHOSPHATASE
(Staphylococcus
aureus) 		5 / 12 GLY A 219
LEU A 222
GLN A 224
ALA A 226
ASP A   9
 None
 1.03A 3gwvA-5f1mA:
undetectable		 3gwvA-5f1mA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA502_0
(OXIDOREDUCTASE,
FMN-BINDING)		 5f1m PHOSPHORYLATED
PROTEIN PHOSPHATASE
(Staphylococcus
aureus) 		4 / 7 THR A 135
ASN A 142
LEU A 146
PHE A 179
 None
 1.39A 4awuA-5f1mA:
undetectable		 4awuA-5f1mA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 5f1m PHOSPHORYLATED
PROTEIN PHOSPHATASE
(Staphylococcus
aureus) 		5 / 12 GLY A  38
GLY A  40
ASP A 233
MET A  99
ASN A 234
 MN  A 302 (-3.9A)
MN  A 302 ( 4.7A)
MN  A 301 (-2.4A)
None
None
 1.15A 4fr0A-5f1mA:
undetectable		 4fr0A-5f1mA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1102_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 5f1m PHOSPHORYLATED
PROTEIN PHOSPHATASE
(Staphylococcus
aureus) 		4 / 7 PHE A 237
ILE A 126
TYR A 188
HIS A 218
 None
 1.12A 4g5jA-5f1mA:
undetectable		 4g5jA-5f1mA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA608_0
(SERUM ALBUMIN)		 5f1m PHOSPHORYLATED
PROTEIN PHOSPHATASE
(Staphylococcus
aureus) 		4 / 4 PRO A 176
ASP A 177
LEU A 178
ARG A  76
 None
 1.35A 4luhA-5f1mA:
0.1		 4luhA-5f1mA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKN_B_KANB403_1
(L-LACTATE
DEHYDROGENASE A
CHAIN)		 5f1m PHOSPHORYLATED
PROTEIN PHOSPHATASE
(Staphylococcus
aureus) 		5 / 9 VAL A 108
TYR A  25
ALA A   4
ILE A 238
ILE A  23
 None
 1.24A 4oknB-5f1mA:
undetectable		 4oknB-5f1mA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5f1m PHOSPHORYLATED
PROTEIN PHOSPHATASE
(Staphylococcus
aureus) 		5 / 12 GLU A 216
PHE A   7
ALA A 226
PHE A 237
LEU A 190
 None
 1.23A 4retA-5f1mA:
undetectable		 4retA-5f1mA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_0
(HYDG PROTEIN)		 5f1m PHOSPHORYLATED
PROTEIN PHOSPHATASE
(Staphylococcus
aureus) 		5 / 12 VAL A 174
ASN A  83
LEU A  86
LEU A  56
LEU A  32
 None
 1.44A 4rtbA-5f1mA:
undetectable		 4rtbA-5f1mA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5f1m PHOSPHORYLATED
PROTEIN PHOSPHATASE
(Staphylococcus
aureus) 		3 / 3 THR A 170
MET A  99
HIS A  42
 None
 1.00A 5uunA-5f1mA:
undetectable		 5uunA-5f1mA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 5f1m PHOSPHORYLATED
PROTEIN PHOSPHATASE
(Staphylococcus
aureus) 		5 / 12 LEU A 183
THR A 135
ILE A 134
ALA A   4
LEU A  33
 None
 1.22A 6ie8A-5f1mA:
undetectable		 6ie8A-5f1mA:
20.15