SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f1p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UAY_A_ADNA1001_1
(TYPE II
3-HYDROXYACYL-COA
DEHYDROGENASE)		 5f1p PTMO8
(Streptomyces
platensis) 		7 / 11 GLY A  13
ALA A  15
SER A  16
ASP A  37
LEU A  38
ASP A  64
VAL A 119
 None
 0.57A 1uayA-5f1pA:
26.1		 1uayA-5f1pA:
32.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UAY_B_ADNB1002_1
(TYPE II
3-HYDROXYACYL-COA
DEHYDROGENASE)		 5f1p PTMO8
(Streptomyces
platensis) 		7 / 10 GLY A  13
ALA A  15
SER A  16
ASP A  37
LEU A  38
ASP A  64
VAL A 119
 None
 0.60A 1uayB-5f1pA:
26.6		 1uayB-5f1pA:
32.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5f1p PTMO8
(Streptomyces
platensis) 		3 / 3 ASP A  37
ASP A  64
ASN A  91
 None
 0.56A 2bm9D-5f1pA:
5.3		 2bm9D-5f1pA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 5f1p PTMO8
(Streptomyces
platensis) 		5 / 12 ILE A  61
GLY A  13
ALA A  34
LEU A  35
ALA A  92
 None
 1.15A 2yvlB-5f1pA:
7.6		 2yvlB-5f1pA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 5f1p PTMO8
(Streptomyces
platensis) 		5 / 12 GLY A 123
ALA A 167
LEU A 168
ASP A  67
VAL A 126
 None
 1.19A 2yvlD-5f1pA:
7.6		 2yvlD-5f1pA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 5f1p PTMO8
(Streptomyces
platensis) 		3 / 3 THR A  45
ASP A  39
GLU A  62
 None
 0.86A 3qowA-5f1pA:
3.3		 3qowA-5f1pA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 5f1p PTMO8
(Streptomyces
platensis) 		3 / 3 ASP A 221
ARG A 218
ASP A 245
 None
 0.76A 4fp9C-5f1pA:
4.1		 4fp9C-5f1pA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 5f1p PTMO8
(Streptomyces
platensis) 		3 / 3 ASP A 221
ARG A 218
ASP A 245
 None
 0.71A 4fp9F-5f1pA:
7.2		 4fp9F-5f1pA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_B_MTXB301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 5f1p PTMO8
(Streptomyces
platensis) 		5 / 11 GLY A 139
GLY A 140
GLY A 141
ALA A 137
HIS A 134
 None
 1.16A 4l8fB-5f1pA:
3.8		 4l8fB-5f1pA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_D_MTXD301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 5f1p PTMO8
(Streptomyces
platensis) 		5 / 11 GLY A 139
GLY A 140
GLY A 141
ALA A 137
HIS A 134
 None
 1.16A 4l8fD-5f1pA:
3.9		 4l8fD-5f1pA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 5f1p PTMO8
(Streptomyces
platensis) 		4 / 8 ALA A  78
MET A  74
THR A  22
VAL A 226
 None
 1.04A 4ltwA-5f1pA:
undetectable		 4ltwA-5f1pA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 5f1p PTMO8
(Streptomyces
platensis) 		4 / 8 LEU A 171
ASN A 145
LEU A 132
ILE A  87
 None
 1.03A 4ok1A-5f1pA:
undetectable		 4ok1A-5f1pA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_A_SAMA401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 5f1p PTMO8
(Streptomyces
platensis) 		5 / 11 GLY A  13
THR A  22
ASP A  37
LEU A  38
ASP A  64
 None
 0.97A 4pghA-5f1pA:
6.4		 4pghA-5f1pA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 5f1p PTMO8
(Streptomyces
platensis) 		3 / 3 THR A  45
ASP A  39
GLU A  62
 None
 0.83A 5fa8A-5f1pA:
6.3		 5fa8A-5f1pA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 5f1p PTMO8
(Streptomyces
platensis) 		5 / 12 LEU A  26
VAL A  33
THR A  12
GLY A  13
MET A  74
 None
 1.35A 6brdA-5f1pA:
4.3		 6brdA-5f1pA:
17.36