SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f1q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5f1q PERIPLASMIC
DIPEPTIDE TRANSPORT
PROTEIN
(Yersinia
pestis) 		4 / 7 ILE A 246
PRO A  39
PHE A  42
ALA A  55
 None
None
EDO  A 610 ( 4.9A)
None
 1.02A 1oniD-5f1qA:
undetectable
1oniE-5f1qA:
undetectable		 1oniD-5f1qA:
14.00
1oniE-5f1qA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5f1q PERIPLASMIC
DIPEPTIDE TRANSPORT
PROTEIN
(Yersinia
pestis) 		3 / 3 ASN A  62
TRP A 233
GLN A 102
 None
 1.17A 1xoqA-5f1qA:
undetectable		 1xoqA-5f1qA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5f1q PERIPLASMIC
DIPEPTIDE TRANSPORT
PROTEIN
(Yersinia
pestis) 		4 / 6 TYR A 519
TYR A  33
ASP A 530
ASN A 531
 None
 1.22A 2g72A-5f1qA:
undetectable		 2g72A-5f1qA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1291_1
(FICOLIN-2)		 5f1q PERIPLASMIC
DIPEPTIDE TRANSPORT
PROTEIN
(Yersinia
pestis) 		4 / 4 ASP A 451
LEU A 151
GLY A 149
ARG A 169
 GOL  A 602 (-2.7A)
None
None
GOL  A 602 ( 4.3A)
 1.42A 2j2pD-5f1qA:
undetectable
2j2pE-5f1qA:
undetectable		 2j2pD-5f1qA:
18.20
2j2pE-5f1qA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 5f1q PERIPLASMIC
DIPEPTIDE TRANSPORT
PROTEIN
(Yersinia
pestis) 		5 / 12 TYR A  91
LEU A 167
ILE A 152
LEU A 151
PHE A 122
 None
 1.17A 2qo6A-5f1qA:
undetectable		 2qo6A-5f1qA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_A_PRLA1188_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 5f1q PERIPLASMIC
DIPEPTIDE TRANSPORT
PROTEIN
(Yersinia
pestis) 		4 / 8 ILE A 185
ASP A 117
ARG A 111
TRP A 101
 None
 1.10A 2v57A-5f1qA:
undetectable		 2v57A-5f1qA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_1
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT)		 5f1q PERIPLASMIC
DIPEPTIDE TRANSPORT
PROTEIN
(Yersinia
pestis) 		5 / 10 LEU A  78
TYR A 120
GLY A 209
GLY A 211
TRP A 233
 None
 1.26A 3ls4H-5f1qA:
undetectable		 3ls4H-5f1qA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 5f1q PERIPLASMIC
DIPEPTIDE TRANSPORT
PROTEIN
(Yersinia
pestis) 		3 / 3 THR A 210
ASP A 117
GLU A 189
 None
 0.67A 3qowA-5f1qA:
undetectable		 3qowA-5f1qA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 5f1q PERIPLASMIC
DIPEPTIDE TRANSPORT
PROTEIN
(Yersinia
pestis) 		4 / 7 SER A 184
GLY A 525
GLY A  50
GLU A  36
 None
GLN  A 608 (-3.8A)
GLN  A 608 ( 3.2A)
None
 0.79A 4koeA-5f1qA:
3.2
4koeB-5f1qA:
3.1
4koeD-5f1qA:
undetectable		 4koeA-5f1qA:
23.29
4koeB-5f1qA:
23.29
4koeD-5f1qA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NED_A_PFNA709_1
(LACTOTRANSFERRIN)		 5f1q PERIPLASMIC
DIPEPTIDE TRANSPORT
PROTEIN
(Yersinia
pestis) 		4 / 6 ASP A 177
ASP A 441
SER A 449
PHE A 182
 None
 1.14A 4nedA-5f1qA:
4.9		 4nedA-5f1qA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 5f1q PERIPLASMIC
DIPEPTIDE TRANSPORT
PROTEIN
(Yersinia
pestis) 		5 / 12 GLY A 209
ILE A 185
ASN A  62
PRO A  44
GLN A 125
 None
 1.29A 4rtpA-5f1qA:
undetectable		 4rtpA-5f1qA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 5f1q PERIPLASMIC
DIPEPTIDE TRANSPORT
PROTEIN
(Yersinia
pestis) 		4 / 7 GLY A 525
GLY A  50
GLU A  36
SER A 184
 GLN  A 608 (-3.8A)
GLN  A 608 ( 3.2A)
None
None
 0.77A 4z53A-5f1qA:
3.5
4z53B-5f1qA:
3.2		 4z53A-5f1qA:
23.47
4z53B-5f1qA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZO1_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 5f1q PERIPLASMIC
DIPEPTIDE TRANSPORT
PROTEIN
(Yersinia
pestis) 		5 / 12 ILE A 374
ALA A 393
ARG A 390
LEU A 376
PHE A 372
 None
 1.46A 4zo1X-5f1qA:
undetectable		 4zo1X-5f1qA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 5f1q PERIPLASMIC
DIPEPTIDE TRANSPORT
PROTEIN
(Yersinia
pestis) 		3 / 3 THR A 210
ASP A 117
GLU A 189
 None
 0.80A 5fa8A-5f1qA:
undetectable		 5fa8A-5f1qA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5f1q PERIPLASMIC
DIPEPTIDE TRANSPORT
PROTEIN
(Yersinia
pestis) 		5 / 10 PHE A  47
SER A  49
GLY A  50
ILE A 224
ALA A  55
 None
GLN  A 609 (-4.9A)
GLN  A 608 ( 3.2A)
None
None
 1.02A 5zjiA-5f1qA:
undetectable
5zjiJ-5f1qA:
undetectable		 5zjiA-5f1qA:
9.74
5zjiJ-5f1qA:
7.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 5f1q PERIPLASMIC
DIPEPTIDE TRANSPORT
PROTEIN
(Yersinia
pestis) 		4 / 8 LEU A  78
GLU A  66
TRP A 233
THR A 210
 None
 1.15A 6c71B-5f1qA:
undetectable		 6c71B-5f1qA:
10.96