SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f1u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA154_1
(CALMODULIN)		 5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Campylobacter
jejuni) 		5 / 10 GLU A  64
ALA A  66
LEU A  54
GLU A  58
GLU A  57
 None
 1.31A 1a29A-5f1uA:
undetectable		 1a29A-5f1uA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D0V_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Campylobacter
jejuni) 		4 / 8 THR A 222
GLY A   8
GLY A 202
LEU A 199
 None
 0.74A 1d0vA-5f1uA:
undetectable		 1d0vA-5f1uA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Campylobacter
jejuni) 		5 / 12 ALA A  81
ALA A  79
PHE A  95
LEU A  92
ALA A  93
 None
 1.10A 1fbyA-5f1uA:
undetectable		 1fbyA-5f1uA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Campylobacter
jejuni) 		4 / 8 THR A 222
GLY A   8
GLY A 202
LEU A 199
 None
 0.73A 1jhaA-5f1uA:
1.8		 1jhaA-5f1uA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_B_ADNB902_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Campylobacter
jejuni) 		5 / 11 ILE A 207
THR A 210
ASN A 244
VAL A 139
TYR A 137
 None
 1.45A 2gl0B-5f1uA:
undetectable
2gl0C-5f1uA:
undetectable		 2gl0B-5f1uA:
22.37
2gl0C-5f1uA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_D_MTXD617_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Campylobacter
jejuni) 		5 / 12 LEU A 247
LEU A 213
THR A  48
ILE A  14
LEU A  30
 None
 1.16A 2oipD-5f1uA:
undetectable		 2oipD-5f1uA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Campylobacter
jejuni) 		5 / 12 LEU A 105
ILE A   5
GLY A 203
ILE A 198
LEU A 135
 None
 0.98A 3ogqB-5f1uA:
undetectable		 3ogqB-5f1uA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Campylobacter
jejuni) 		4 / 7 LEU A  78
ASP A 102
ALA A 101
TYR A 163
 None
 0.97A 3rodD-5f1uA:
undetectable		 3rodD-5f1uA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Campylobacter
jejuni) 		4 / 5 TYR A 196
ILE A 246
LEU A 247
LYS A 245
 None
 1.30A 3sueC-5f1uA:
undetectable		 3sueC-5f1uA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Campylobacter
jejuni) 		5 / 12 TYR A 123
LEU A 155
ASN A 161
LYS A 166
LEU A  78
 None
 1.20A 3vywD-5f1uA:
undetectable		 3vywD-5f1uA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_A_9TPA601_1
(SERUM ALBUMIN)		 5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Campylobacter
jejuni) 		5 / 12 LEU A 155
ILE A 126
HIS A 122
LEU A 135
GLY A  82
 None
 1.26A 4l9qA-5f1uA:
undetectable		 4l9qA-5f1uA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_B_SAMB301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Campylobacter
jejuni) 		5 / 12 ALA A 225
GLY A 202
LEU A 178
LEU A 179
LYS A 174
 None
 1.10A 4lg1B-5f1uA:
undetectable		 4lg1B-5f1uA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Campylobacter
jejuni) 		5 / 12 ASN A 252
GLU A 191
GLY A 190
ILE A 198
ILE A 188
 None
 1.39A 4xucA-5f1uA:
undetectable		 4xucA-5f1uA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Campylobacter
jejuni) 		4 / 4 LEU A  54
TYR A 137
PRO A  44
ILE A  63
 None
 1.39A 5esgA-5f1uA:
undetectable		 5esgA-5f1uA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Campylobacter
jejuni) 		5 / 12 VAL A  90
ALA A 125
SER A 129
GLN A 116
LEU A 155
 None
 1.28A 5m54B-5f1uA:
2.1		 5m54B-5f1uA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Campylobacter
jejuni) 		5 / 12 VAL A  90
ALA A 125
SER A 129
GLN A 116
LEU A 155
 None
 1.27A 5m54E-5f1uA:
2.4		 5m54E-5f1uA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Campylobacter
jejuni) 		4 / 7 HIS A 122
LEU A 119
VAL A 107
SER A 106
 None
 0.98A 5m8rA-5f1uA:
undetectable		 5m8rA-5f1uA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Campylobacter
jejuni) 		4 / 8 HIS A 122
LEU A 119
VAL A 107
SER A 106
 None
 1.00A 5m8rB-5f1uA:
undetectable		 5m8rB-5f1uA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Campylobacter
jejuni) 		4 / 8 HIS A 122
LEU A 119
VAL A 107
SER A 106
 None
 0.94A 5m8rD-5f1uA:
undetectable		 5m8rD-5f1uA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OCS_A_ACTA402_0
(PUTATIVE
NADH-DEPENTDENT
FLAVIN
OXIDOREDUCTASE)		 5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Campylobacter
jejuni) 		4 / 5 CYH A 145
ILE A 147
HIS A 122
TYR A 123
 None
 1.09A 5ocsA-5f1uA:
10.6		 5ocsA-5f1uA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OCS_A_ACTA402_0
(PUTATIVE
NADH-DEPENTDENT
FLAVIN
OXIDOREDUCTASE)		 5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Campylobacter
jejuni) 		4 / 5 CYH A 145
ILE A 147
HIS A 122
TYR A 123
 None
 1.42A 5ocsA-5f1uA:
10.6		 5ocsA-5f1uA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OCS_C_ACTC402_0
(PUTATIVE
NADH-DEPENTDENT
FLAVIN
OXIDOREDUCTASE)		 5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Campylobacter
jejuni) 		4 / 5 CYH A 145
ILE A 147
HIS A 122
TYR A 123
 None
 1.07A 5ocsC-5f1uA:
9.5		 5ocsC-5f1uA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OCS_C_ACTC402_0
(PUTATIVE
NADH-DEPENTDENT
FLAVIN
OXIDOREDUCTASE)		 5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Campylobacter
jejuni) 		4 / 5 CYH A 145
ILE A 147
HIS A 122
TYR A 123
 None
 1.42A 5ocsC-5f1uA:
9.5		 5ocsC-5f1uA:
21.37