SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f1y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5f1y MCCC FAMILY PROTEIN
(Bacillus
cereus) 		4 / 5 GLY A  90
GLN A  91
VAL A 219
SER A  93
 None
 1.24A 1p6kB-5f1yA:
undetectable		 1p6kB-5f1yA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PNL_B_PACB559_0
(PENICILLIN
AMIDOHYDROLASE)		 5f1y MCCC FAMILY PROTEIN
(Bacillus
cereus) 		4 / 8 MET A 113
PHE A 142
ILE A 319
ASN A 157
 None
 1.18A 1pnlA-5f1yA:
undetectable
1pnlB-5f1yA:
undetectable		 1pnlA-5f1yA:
21.45
1pnlB-5f1yA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5f1y MCCC FAMILY PROTEIN
(Bacillus
cereus) 		4 / 5 GLY A  90
GLN A  91
VAL A 219
SER A  93
 None
 1.26A 1rs6B-5f1yA:
undetectable		 1rs6B-5f1yA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_1
(DIHYDROFOLATE
REDUCTASE)		 5f1y MCCC FAMILY PROTEIN
(Bacillus
cereus) 		5 / 12 ILE A 100
ALA A 104
GLN A  66
PRO A  52
ASN A  53
 None
 1.23A 1u70A-5f1yA:
undetectable		 1u70A-5f1yA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5f1y MCCC FAMILY PROTEIN
(Bacillus
cereus) 		4 / 5 GLY A  90
GLN A  91
VAL A 219
SER A  93
 None
 1.25A 1zzuB-5f1yA:
undetectable		 1zzuB-5f1yA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 5f1y MCCC FAMILY PROTEIN
(Bacillus
cereus) 		4 / 6 SER A 131
SER A 324
LEU A 212
GLY A 323
 None
 1.04A 2j2pD-5f1yA:
undetectable
2j2pF-5f1yA:
undetectable		 2j2pD-5f1yA:
21.43
2j2pF-5f1yA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1103_0
(FERROCHELATASE)		 5f1y MCCC FAMILY PROTEIN
(Bacillus
cereus) 		4 / 8 MET A 113
ARG A 158
VAL A 342
GLY A 341
 None
 1.10A 2qd5B-5f1yA:
2.3		 2qd5B-5f1yA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 5f1y MCCC FAMILY PROTEIN
(Bacillus
cereus) 		3 / 3 SER A 131
SER A 132
HIS A 234
 None
 0.72A 3mzeA-5f1yA:
undetectable		 3mzeA-5f1yA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRI_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 5f1y MCCC FAMILY PROTEIN
(Bacillus
cereus) 		5 / 10 TYR A 283
TYR A 287
SER A 245
TRP A 257
ILE A 217
 None
 1.22A 3vriA-5f1yA:
undetectable
3vriC-5f1yA:
undetectable		 3vriA-5f1yA:
22.83
3vriC-5f1yA:
3.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRJ_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 5f1y MCCC FAMILY PROTEIN
(Bacillus
cereus) 		5 / 12 TYR A 283
TYR A 287
SER A 245
TRP A 257
ILE A 217
 None
 1.19A 3vrjA-5f1yA:
undetectable
3vrjC-5f1yA:
undetectable		 3vrjA-5f1yA:
22.83
3vrjC-5f1yA:
3.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BWL_C_MN9C1297_0
(N-ACETYLNEURAMINATE
LYASE)		 5f1y MCCC FAMILY PROTEIN
(Bacillus
cereus) 		5 / 10 ILE A  88
ASP A  26
GLU A  28
GLY A  57
SER A  58
 None
 1.17A 4bwlC-5f1yA:
undetectable		 4bwlC-5f1yA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5f1y MCCC FAMILY PROTEIN
(Bacillus
cereus) 		5 / 12 ILE A 328
PHE A 335
LEU A 320
PRO A 321
ILE A 274
 None
 1.05A 4p3qA-5f1yA:
undetectable		 4p3qA-5f1yA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_1
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 5f1y MCCC FAMILY PROTEIN
(Bacillus
cereus) 		3 / 3 SER A  93
GLU A 246
GLU A 315
 None
 0.85A 4ymgB-5f1yA:
undetectable		 4ymgB-5f1yA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_D_READ602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 5f1y MCCC FAMILY PROTEIN
(Bacillus
cereus) 		5 / 12 ILE A 217
GLU A 243
GLY A 215
ASN A 260
LEU A 240
 None
 1.25A 5fhzD-5f1yA:
undetectable		 5fhzD-5f1yA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 5f1y MCCC FAMILY PROTEIN
(Bacillus
cereus) 		4 / 7 TYR A 115
HIS A 313
TYR A 134
VAL A 219
 None
 1.29A 6g2pA-5f1yA:
undetectable		 6g2pA-5f1yA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5f1y MCCC FAMILY PROTEIN
(Bacillus
cereus) 		4 / 5 TYR A 134
VAL A  14
PHE A 318
GLY A 312
 None
 1.42A 6hd4A-5f1yA:
undetectable		 6hd4A-5f1yA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5f1y MCCC FAMILY PROTEIN
(Bacillus
cereus) 		4 / 5 TYR A 322
VAL A  14
PHE A 311
GLY A 215
 None
 1.41A 6hd4A-5f1yA:
undetectable		 6hd4A-5f1yA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5f1y MCCC FAMILY PROTEIN
(Bacillus
cereus) 		5 / 6 LEU A 320
TYR A 134
VAL A  14
PHE A 318
GLY A 312
 None
 1.43A 6hd4B-5f1yA:
undetectable		 6hd4B-5f1yA:
13.44