SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f22'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 5f22 NON-STRUCTURAL
PROTEIN
(Severe
acute
respiratory
syndrome-related
coronavirus) 		4 / 7 THR B 142
ALA B 155
ASN B 110
LEU B 133
 None
 0.98A 2hzqA-5f22B:
undetectable		 2hzqA-5f22B:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5f22 NON-STRUCTURAL
PROTEIN
(Severe
acute
respiratory
syndrome-related
coronavirus) 		5 / 12 ASN B 110
LEU B 108
ALA B 107
LEU B 133
THR B 146
 None
 1.09A 2oaxB-5f22B:
undetectable		 2oaxB-5f22B:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 5f22 NON-STRUCTURAL
PROTEIN
(Severe
acute
respiratory
syndrome-related
coronavirus) 		5 / 12 ASN B 110
LEU B 108
ALA B 107
LEU B 133
THR B 146
 None
 1.14A 2oaxF-5f22B:
undetectable		 2oaxF-5f22B:
18.67