SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f2v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 5f2v GTP
PYROPHOSPHOKINASE
YJBM
(Bacillus
subtilis) 		3 / 3 GLN V  81
HIS V  37
PRO V  39
 None
 0.92A 1d8cA-5f2vV:
undetectable		 1d8cA-5f2vV:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 5f2v GTP
PYROPHOSPHOKINASE
YJBM
(Bacillus
subtilis) 		3 / 4 LYS V  56
ALA V  57
MET V  70
 APC  V 301 (-2.8A)
None
None
 0.99A 1hk3A-5f2vV:
2.4		 1hk3A-5f2vV:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 5f2v GTP
PYROPHOSPHOKINASE
YJBM
(Bacillus
subtilis) 		3 / 3 ARG V 143
ILE V 153
TRP V 150
 APC  V 301 ( 4.9A)
None
None
 1.01A 1m8eB-5f2vV:
undetectable		 1m8eB-5f2vV:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 5f2v GTP
PYROPHOSPHOKINASE
YJBM
(Bacillus
subtilis) 		3 / 3 ARG V 143
ILE V 153
TRP V 150
 APC  V 301 ( 4.9A)
None
None
 0.97A 1nodB-5f2vV:
undetectable		 1nodB-5f2vV:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 5f2v GTP
PYROPHOSPHOKINASE
YJBM
(Bacillus
subtilis) 		3 / 3 ARG V 143
ILE V 153
TRP V 150
 APC  V 301 ( 4.9A)
None
None
 0.93A 1qomA-5f2vV:
undetectable		 1qomA-5f2vV:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_A_H4BA1290_1
(PTERIDINE REDUCTASE
1)		 5f2v GTP
PYROPHOSPHOKINASE
YJBM
(Bacillus
subtilis) 		4 / 8 ASP V  98
LEU V  20
LEU V  93
LEU V 121
 None
 0.95A 2bfpA-5f2vV:
undetectable		 2bfpA-5f2vV:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 5f2v GTP
PYROPHOSPHOKINASE
YJBM
(Bacillus
subtilis) 		4 / 8 ASP V  98
LEU V  20
LEU V  93
LEU V 121
 None
 0.84A 2bfpD-5f2vV:
undetectable		 2bfpD-5f2vV:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 5f2v GTP
PYROPHOSPHOKINASE
YJBM
(Bacillus
subtilis) 		3 / 3 ARG V 143
ILE V 153
TRP V 150
 APC  V 301 ( 4.9A)
None
None
 0.97A 2nodB-5f2vV:
undetectable		 2nodB-5f2vV:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5f2v GTP
PYROPHOSPHOKINASE
YJBM
(Bacillus
subtilis) 		3 / 3 ARG V 143
ILE V 153
TRP V 150
 APC  V 301 ( 4.9A)
None
None
 1.02A 3e68A-5f2vV:
undetectable		 3e68A-5f2vV:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5f2v GTP
PYROPHOSPHOKINASE
YJBM
(Bacillus
subtilis) 		3 / 3 ARG V 143
ILE V 153
TRP V 150
 APC  V 301 ( 4.9A)
None
None
 0.97A 3e6tB-5f2vV:
undetectable		 3e6tB-5f2vV:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5f2v GTP
PYROPHOSPHOKINASE
YJBM
(Bacillus
subtilis) 		3 / 3 ARG V 143
ILE V 153
TRP V 150
 APC  V 301 ( 4.9A)
None
None
 0.92A 3e7iB-5f2vV:
undetectable		 3e7iB-5f2vV:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5f2v GTP
PYROPHOSPHOKINASE
YJBM
(Bacillus
subtilis) 		3 / 3 ARG V 143
ILE V 153
TRP V 150
 APC  V 301 ( 4.9A)
None
None
 1.03A 3nw2A-5f2vV:
undetectable		 3nw2A-5f2vV:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5f2v GTP
PYROPHOSPHOKINASE
YJBM
(Bacillus
subtilis) 		3 / 3 ARG V 143
ILE V 153
TRP V 150
 APC  V 301 ( 4.9A)
None
None
 0.98A 3nw2B-5f2vV:
undetectable		 3nw2B-5f2vV:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_1
(METHYLTRANSFERASE
WBDD)		 5f2v GTP
PYROPHOSPHOKINASE
YJBM
(Bacillus
subtilis) 		3 / 3 GLN V 195
ASP V  85
GLN V  81
 None
 0.81A 4aztA-5f2vV:
undetectable		 4aztA-5f2vV:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5f2v GTP
PYROPHOSPHOKINASE
YJBM
(Bacillus
subtilis) 		4 / 8 SER V  38
ARG V  28
ILE V  40
ASP V  85
 None
 1.11A 4d33A-5f2vV:
undetectable		 4d33A-5f2vV:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5f2v GTP
PYROPHOSPHOKINASE
YJBM
(Bacillus
subtilis) 		4 / 7 SER V  38
ARG V  28
ILE V  40
ASP V  85
 None
 1.12A 4d33B-5f2vV:
undetectable		 4d33B-5f2vV:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5f2v GTP
PYROPHOSPHOKINASE
YJBM
(Bacillus
subtilis) 		4 / 8 SER V  38
ARG V  28
ILE V  40
ASP V  85
 None
 1.09A 4d39A-5f2vV:
undetectable		 4d39A-5f2vV:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5f2v GTP
PYROPHOSPHOKINASE
YJBM
(Bacillus
subtilis) 		4 / 7 SER V  38
ARG V  28
ILE V  40
ASP V  85
 None
 1.11A 4d39B-5f2vV:
undetectable		 4d39B-5f2vV:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)		 5f2v GTP
PYROPHOSPHOKINASE
YJBM
(Bacillus
subtilis) 		5 / 12 LEU V  93
VAL V  89
LEU V 145
ILE V 142
ILE V 140
 None
 0.93A 4ltwA-5f2vV:
undetectable		 4ltwA-5f2vV:
19.78