SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f3j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 5f3j ANTIBODY 2D10 SINGLE
CHAIN VARIABLE
FRAGMENT
(Mus
musculus) 		3 / 3 THR C 284
THR C 283
PRO C 178
 None
 0.84A 1a7yA-5f3jC:
undetectable		 1a7yA-5f3jC:
4.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 5f3j ANTIBODY 2D10 SINGLE
CHAIN VARIABLE
FRAGMENT
(Mus
musculus) 		8 / 12 GLN C 133
TYR C 138
LEU C 140
PHE C 142
TRP C 202
ASN C 204
VAL C 206
ALA C 266
 None
 0.73A 1h8sA-5f3jC:
28.5		 1h8sA-5f3jC:
58.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 5f3j ANTIBODY 2D10 SINGLE
CHAIN VARIABLE
FRAGMENT
(Mus
musculus) 		8 / 12 TYR C 138
LEU C 140
PHE C 142
TRP C 202
ASN C 204
VAL C 206
ALA C 266
TRP C 279
 None
 0.82A 1h8sA-5f3jC:
28.5		 1h8sA-5f3jC:
58.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRQ_A_STRA501_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 5f3j ANTIBODY 2D10 SINGLE
CHAIN VARIABLE
FRAGMENT
(Mus
musculus) 		5 / 11 LEU C 148
GLU C  56
VAL C  52
LEU C  91
LEU C 117
 None
 1.36A 1mrqA-5f3jC:
undetectable		 1mrqA-5f3jC:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 5f3j ANTIBODY 2D10 SINGLE
CHAIN VARIABLE
FRAGMENT
(Mus
musculus) 		3 / 3 THR C 284
THR C 283
PRO C 178
 None
 0.84A 1qfiA-5f3jC:
undetectable		 1qfiA-5f3jC:
4.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5f3j ANTIBODY 2D10 SINGLE
CHAIN VARIABLE
FRAGMENT
(Mus
musculus) 		5 / 7 GLY C 223
PRO C 222
THR C 227
ILE C 220
GLY C 225
 None
 1.15A 1usqA-5f3jC:
undetectable		 1usqA-5f3jC:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5f3j ANTIBODY 2D10 SINGLE
CHAIN VARIABLE
FRAGMENT
(Mus
musculus) 		4 / 6 GLY C 223
PRO C 222
ILE C 220
GLY C 225
 None
 0.81A 1usqB-5f3jC:
undetectable		 1usqB-5f3jC:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5f3j ANTIBODY 2D10 SINGLE
CHAIN VARIABLE
FRAGMENT
(Mus
musculus) 		4 / 6 GLY C 223
PRO C 222
ILE C 220
GLY C 225
 None
 0.81A 1usqC-5f3jC:
undetectable		 1usqC-5f3jC:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5f3j ANTIBODY 2D10 SINGLE
CHAIN VARIABLE
FRAGMENT
(Mus
musculus) 		4 / 6 GLY C 223
PRO C 222
ILE C 220
GLY C 225
 None
 0.82A 1usqD-5f3jC:
2.3		 1usqD-5f3jC:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5f3j ANTIBODY 2D10 SINGLE
CHAIN VARIABLE
FRAGMENT
(Mus
musculus) 		4 / 6 GLY C 223
PRO C 222
ILE C 220
GLY C 225
 None
 0.82A 1usqE-5f3jC:
2.4		 1usqE-5f3jC:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5f3j ANTIBODY 2D10 SINGLE
CHAIN VARIABLE
FRAGMENT
(Mus
musculus) 		5 / 7 GLY C 223
PRO C 222
THR C 227
ILE C 220
GLY C 225
 None
 1.16A 2jklA-5f3jC:
undetectable		 2jklA-5f3jC:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5f3j ANTIBODY 2D10 SINGLE
CHAIN VARIABLE
FRAGMENT
(Mus
musculus) 		4 / 6 GLY C 223
PRO C 222
ILE C 220
GLY C 225
 None
 0.86A 2jklB-5f3jC:
undetectable		 2jklB-5f3jC:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5f3j ANTIBODY 2D10 SINGLE
CHAIN VARIABLE
FRAGMENT
(Mus
musculus) 		5 / 7 GLY C 223
PRO C 222
THR C 227
ILE C 220
GLY C 225
 None
 1.17A 2jklC-5f3jC:
2.2		 2jklC-5f3jC:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5f3j ANTIBODY 2D10 SINGLE
CHAIN VARIABLE
FRAGMENT
(Mus
musculus) 		5 / 7 GLY C 223
PRO C 222
THR C 227
ILE C 220
GLY C 225
 None
 1.16A 2jklD-5f3jC:
2.3		 2jklD-5f3jC:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5f3j ANTIBODY 2D10 SINGLE
CHAIN VARIABLE
FRAGMENT
(Mus
musculus) 		5 / 7 GLY C 223
PRO C 222
THR C 227
ILE C 220
GLY C 225
 None
 1.16A 2jklF-5f3jC:
undetectable		 2jklF-5f3jC:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_A_SAMA500_0
(HYPOTHETICAL PROTEIN)		 5f3j ANTIBODY 2D10 SINGLE
CHAIN VARIABLE
FRAGMENT
(Mus
musculus) 		4 / 7 VAL C 181
ALA C 185
PRO C 178
THR C 283
 None
 0.90A 2q6oA-5f3jC:
undetectable		 2q6oA-5f3jC:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 5f3j ANTIBODY 2D10 SINGLE
CHAIN VARIABLE
FRAGMENT
(Mus
musculus) 		4 / 5 LYS C 182
PRO C 183
SER C 257
SER C 254
 None
 1.24A 3ijxH-5f3jC:
undetectable		 3ijxH-5f3jC:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 5f3j ANTIBODY 2D10 SINGLE
CHAIN VARIABLE
FRAGMENT
(Mus
musculus) 		4 / 5 LYS C 182
PRO C 183
SER C 257
SER C 254
 None
 1.39A 3iluH-5f3jC:
undetectable		 3iluH-5f3jC:
20.38